Preferably called dibenzosuberane (other less common names are Dibenzocycloheptene and dibenzocycloheptadiene) is a
tricyclic chemical compound featuring two
benzene rings bound to a
cycloheptene group. It is an occasional motif in synthetic organic chemistry.
Various
tricyclic antidepressant
Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants, which is important for the management of depression. They are second-line drugs next to SSRIs. TCAs were discovered in the early 1950s and we ...
s (TCAs) contain the dibenzocycloheptene
moiety in their
chemical structures, including
amineptine,
amitriptyline,
amitriptylinoxide,
butriptyline,
demexiptiline
Demexiptiline (brand names Deparon, Tinoran) is a tricyclic antidepressant (TCA) used in France for the treatment of depression. It acts primarily as a norepinephrine reuptake inhibitor similarly to desipramine. Synthesis
The synthesis is sim ...
,
nortriptyline,
noxiptiline
Noxiptiline (brand names Agedal, Elronon, Nogedal), also known as noxiptyline and dibenzoxine, is a tricyclic antidepressant (TCA) that was introduced in Europe in the 1970s for the treatment of depression. It has imipramine-like effects, acti ...
, and
protriptyline
Protriptyline, sold under the brand name Vivactil among others, is a tricyclic antidepressant (TCA), specifically a secondary amine, indicated for the treatment of depression and attention-deficit hyperactivity disorder (ADHD). Uniquely among mo ...
.
Cyclobenzaprine
Cyclobenzaprine (sold under the brand name Flexeril, among others) is a medication used for muscle spasms from musculoskeletal conditions of sudden onset. It is not useful in cerebral palsy. It is taken by mouth. Use is not recommended for mor ...
, a skeletal
muscle relaxant, also contains this functional group.
Numbering System

See also
*
Dibenzazepine
Dibenzazepine (iminostilbene) is a chemical compound with two benzene rings fused to an azepine group.
See also
* Benzazepine
* Dibenzothiazepine
* Dibenzothiepin
* Dibenzoxepin
Dibenzoxepin, or dibenz 'b'',''e''xepin, is a tricyclic compoun ...
*
Dibenzothiepin
*
Dibenzoxepin
*
Dibenzothiazepine
External links
*
References
Tricyclic antidepressants
{{hydrocarbon-stub