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Derealization is an alteration in the perception of the external world, causing those with the condition to perceive it as unreal, distant, distorted, or in other ways falsified. Other symptoms include feeling as if one's environment lacks spontaneity, emotional coloring, and depth. Described as "Experiences of unreality or detachment with respect to surroundings (e.g., individuals or objects are experienced as unreal, dreamlike, foggy, lifeless or visually distorted") in the
DSM-5 The ''Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition'' (DSM-5), is the 2013 update to the '' Diagnostic and Statistical Manual of Mental Disorders'', the taxonomic and diagnostic tool published by the American Psychiat ...
, it is a dissociative symptom that may appear in moments of severe stress. Derealization is a subjective experience pertaining to a person's perception of the outside world, while
depersonalization Depersonalization is a dissociative phenomenon characterized by a subjective feeling of detachment from oneself, manifesting as a sense of disconnection from one's thoughts, emotions, sensations, or actions, and often accompanied by a feeling of ...
is a related symptom characterized by dissociation from one's own body and mental processes. The two are commonly experienced in conjunction but can also occur independently. Chronic derealization is fairly rare, and may be caused by occipitaltemporal dysfunction. Experiencing derealization for long periods of time or having recurring episodes can be indicative of many psychological disorders, and can cause significant distress. Chronic derealization is estimated to occur in between 0.95% and 2.4% of the general population. Derealization is equally prevalent amongst men and women, while the onset usually occurs in adolescence; only 5% of cases of chronic derealization occur in those older than 25. Temporary derealization symptoms are commonly experienced by the general population a few times throughout their lives, with a lifetime prevalence of 26%–74% and a prevalence of 31%–66% at the time of a traumatic event. Derealization is linked to childhood trauma, with its severity correlating directly with the reported severity of childhood maltreatment.


Description

The experience of derealization can be described as feeling as if a substance separates a person from the outside world, such as a sensory fog, pane of glass, or veil. The person may feel as if they are viewing their surroundings through VR glasses, through glass, or on a movie screen. Some report that what they see lacks vividness and emotional coloring. Emotional response to visual recognition of loved ones may be significantly reduced. Feelings of ''
déjà vu ''Déjà vu'' ( , ; "already seen") is the phenomenon of feeling like one has lived through the present situation in the past.Schnider, Armin. (2008). ''The Confabulating Mind: How the Brain Creates Reality''. Oxford University Press. pp. 167–1 ...
'' or '' jamais vu'' are common. One may not be sure whether what one perceives is real. The world may seem as if it were going through a
dolly zoom A dolly zoom (also known as a Hitchcock shot, ''Vertigo'' shot, ''Jaws'' effect, or Zolly shot) is an in-camera effect that appears to undermine normal visual perception. The effect is achieved by Zooming (filmmaking), zooming a zoom lens to a ...
effect. Such perceptual abnormalities may also extend to hearing, taste, and smell. An important differentiation between
hallucination A hallucination is a perception in the absence of an external stimulus that has the compelling sense of reality. They are distinguishable from several related phenomena, such as dreaming ( REM sleep), which does not involve wakefulness; pse ...
and derealization is that one does not hear, see, or experience things that are not real or visible during derealization; rather, one experiences their surroundings as distant or dreamlike. During this state of altered perception, one is aware of the feeling's subjective nature. The degree of familiarity one has with their surroundings is among one's sensory and psychological identity, memory foundation, and history when experiencing a place. People experiencing derealization block this identifying foundation from recall. This "blocking effect" creates a discrepancy of correlation between one's perception of one's surroundings during derealization and what one would perceive in its absence. Frequently, derealization occurs in the context of constant worrying or "
intrusive thought An intrusive thought is an unwelcome, involuntary thought, image, or unpleasant idea that may become an obsession, is upsetting or distressing, and can feel difficult to manage or eliminate. When such thoughts are paired with obsessive–compulsi ...
s" that one finds hard to switch off. In such cases it can build unnoticed along with the underlying anxiety attached to these disturbing thoughts, and be recognized only in the aftermath of a realization of crisis, often a
panic attack Panic attacks are sudden periods of intense fear and Comfort, discomfort that may include palpitations, otherwise defined as a Tachycardia, rapid, Arrhythmia, irregular Heart rate, heartbeat, Hyperhidrosis, sweating, chest pain or discomfort, s ...
, subsequently seeming difficult or impossible to ignore. This type of anxiety can be crippling to the affected and may lead to avoidant behavior. Those who experience this phenomenon may feel concern over the cause of their derealization. It is often difficult to accept that such a disturbing symptom is simply a result of anxiety, and one may think the cause must be something more serious. This can, in turn, cause more anxiety and worsen the derealization. Derealization has also been shown to interfere with the learning process, with cognitive impairments demonstrated in immediate recall and visuospatial deficits. This can be best understood as the feeling of seeing events in third person.


Causes

Derealization can accompany the neurological conditions of
epilepsy Epilepsy is a group of Non-communicable disease, non-communicable Neurological disorder, neurological disorders characterized by a tendency for recurrent, unprovoked Seizure, seizures. A seizure is a sudden burst of abnormal electrical activit ...
(particularly temporal lobe epilepsy), migraine, and mild TBI ( head injury). There is a similarity between visual hypo-emotionality, a reduced emotional response to viewed objects, and derealization. This suggests a disruption of the process by which perception becomes emotionally colored. This qualitative change in the experiencing of perception may lead to reports of anything viewed being unreal or detached. The instances of recurring or chronic derealization among those who have experienced extreme trauma and/or have post-traumatic stress ( PTSD) have been studied closely in many scientific studies, whose results indicate a strong link between the disorders, with a disproportionate amount of post traumatic stress patients reporting recurring feelings of derealization and depersonalization (up to 30% of those with the condition) in comparison to the general populace (only around 2%), especially in those who experienced the trauma in childhood. Many possibilities have been suggested by various psychologists to help explain these findings, the most widely accepted including that experiencing trauma can cause individuals to distance themselves from their surroundings and perception, with the aim of subsequently distancing themselves from the trauma and (especially in the case of depersonalisation) their emotional response to it. This could be either as a deliberate coping mechanism or an involuntary, reflexive response depending on circumstance. This possibly not only increases the risk of experiencing problems with derealization and its corresponding disorder, but with all relevant dissociative disorders. In the case of childhood trauma, not only are children more likely to be susceptible to such a response as they are less able to implement more healthy strategies to deal with the emotional implications of experiencing trauma, there is also a lot of evidence that shows trauma can have a substantial detrimental effect on learning and development, especially since those who experience trauma in childhood are far less likely to have received adequate parenting. Some neurophysiological studies have noted disturbances arising from the frontal-temporal cortex, which could explain the correlation found between derealization symptoms and temporal lobe disorders. This is further supported by reports of people with frontal lobe epilepsy, with those with epilepsy of the dorsal
premotor cortex The premotor cortex is an area of the motor cortex lying within the frontal lobe of the brain just anterior to the primary motor cortex. It occupies part of Brodmann's area 6. It has been studied mainly in primates, including monkeys and human ...
reporting symptoms of depersonalization, while those with
temporal lobe The temporal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in pr ...
epilepsy Epilepsy is a group of Non-communicable disease, non-communicable Neurological disorder, neurological disorders characterized by a tendency for recurrent, unprovoked Seizure, seizures. A seizure is a sudden burst of abnormal electrical activit ...
reported experiencing derealization symptoms. Derealization is a common psychosomatic symptom seen in various anxiety disorders, especially hypochondria. One study suggested multiple explanations for derealisation, one of which being the “intrusions of sleep elements into waking consciousness”, because derealisation has been described as “dream-like”, and because derealisation is related to low levels of norepinephrine, a neurotransmitter regulating alertness, in the urine. These all suggest a link between derealisation and depersonalisation and abnormalities in sleep and wakefulness. Another explanation in the same vein is poor sleep quality, which contributes to rumination— repetitively focusing on one’s own distress and the circumstances surrounding such distress— and seems to either bring about or increase symptoms of derealisation. Rumination and derealisation were found to be linked, as those individuals who had high levels of rumination were more likely to report symptoms of derealisation. Finally, the study suggested that maladaptive emotional regulation was linked to derealisation, and that poor emotional regulation, when combined with high levels of rumination and poor sleep quality, could be the cause of derealisation and depersonalisation disorder. There is a positive correlation between fatigue and derealisation symptoms. Emotional suppression is also linked to derealisation symptoms. A study by Tibubos et al. showed that those who reappraised their emotions, meaning those who changed the way they assessed their situation and their capacity to manage it, thus altering its emotional impact, were less likely to experience derealisation. Conversely, those who suppressed their emotions were both more fatigued and more likely to experience derealisation  and depersonalisation symptoms. Derealisation is often comorbid with depression and anxiety. Symptoms of derealisation are associated with symptoms of both depression and anxiety in the long-term, and those who experience chronic derealisation seem to be more likely to experience depressive and anxious symptoms. Even when controlling for factors like treatment history, family history of mental disorders, childhood trauma, and sociodemographic status, many people who experience derealization also suffer from depression and/or anxiety disorders. However, those who experience derealization are also less likely to experience bodily symptoms of anxiety, compared to those who suffer from anxiety but not derealization, which may reflect the feelings of detachment from the body caused by derealization. Researchers used brain fMRI to check the neural responses of those suffering from derealisation and depersonalisation to both aversive and neutral images. They found that the derealised patients “rated the aversive, disgusting scenes as less emotive than control subjects and, in response to these stimuli, showed reduced activation in structures implicated in the perception of disgust.” While the derealised patients understood the content of the aversive pictures they were shown, they did not experience an emotional response, while the control group did, showing that the neural and behavioural responses of those experiencing derealization and depersonalisation were impaired. Derealization and dissociative symptoms have been linked by some studies to various physiological and psychological differences in individuals and their environments. It was remarked that labile sleep-wake cycles (labile meaning more easily roused) with some distinct changes in sleep, such as dream-like states, hypnogogic, hypnopompic hallucinations, night-terrors and other disorders related to sleep could possibly be causative or improve symptoms to a degree. Derealization can also be a symptom of severe sleep disorders and
mental disorder A mental disorder, also referred to as a mental illness, a mental health condition, or a psychiatric disability, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. A mental disorder is ...
s like depersonalization disorder,
borderline personality disorder Borderline personality disorder (BPD) is a personality disorder characterized by a pervasive, long-term pattern of significant interpersonal relationship instability, an acute fear of Abandonment (emotional), abandonment, and intense emotiona ...
,
bipolar disorder Bipolar disorder (BD), previously known as manic depression, is a mental disorder characterized by periods of Depression (mood), depression and periods of abnormally elevated Mood (psychology), mood that each last from days to weeks, and in ...
,
schizophrenia Schizophrenia () is a mental disorder characterized variously by hallucinations (typically, Auditory hallucination#Schizophrenia, hearing voices), delusions, thought disorder, disorganized thinking and behavior, and Reduced affect display, f ...
, dissociative identity disorder, and other mental conditions.
Cannabis ''Cannabis'' () is a genus of flowering plants in the family Cannabaceae that is widely accepted as being indigenous to and originating from the continent of Asia. However, the number of species is disputed, with as many as three species be ...
, psychedelics, dissociatives,
antidepressant Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction. Common side effects of antidepressants include Xerostomia, dry mouth, weight gain, dizziness, headaches, akathi ...
s,
caffeine Caffeine is a central nervous system (CNS) stimulant of the methylxanthine chemical classification, class and is the most commonly consumed Psychoactive drug, psychoactive substance globally. It is mainly used for its eugeroic (wakefulness pr ...
,
nitrous oxide Nitrous oxide (dinitrogen oxide or dinitrogen monoxide), commonly known as laughing gas, nitrous, or factitious air, among others, is a chemical compound, an Nitrogen oxide, oxide of nitrogen with the Chemical formula, formula . At room te ...
, albuterol, and
nicotine Nicotine is a natural product, naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and ''Duboisia hopwoodii'') and is widely used recreational drug use, recreationally as a stimulant and anxiolytic. As ...
can all produce feelings of derealization, or sensations mimicking them, particularly when taken in excess. It can also result from alcohol withdrawal or benzodiazepine withdrawal. Tramadol withdrawal can also cause feelings of derealization, often alongside psychotic symptoms such as
anxiety Anxiety is an emotion characterised by an unpleasant state of inner wikt:turmoil, turmoil and includes feelings of dread over Anticipation, anticipated events. Anxiety is different from fear in that fear is defined as the emotional response ...
,
paranoia Paranoia is an instinct or thought process that is believed to be heavily influenced by anxiety, suspicion, or fear, often to the point of delusion and irrationality. Paranoid thinking typically includes persecutory beliefs, or beliefs of co ...
and hallucinations. Generally, when derealisation is induced by cannabis, symptoms do not last longer than the period of intoxication, generally subsiding within about 2 hours of exposure. However, a small group of those who use cannabis may experience derealization symptoms lasting weeks, months, or years, even after they stop using cannabis. The most significant factor for this chronic cannabis-induced derealisation seems to be a history of anxiety, and young, anxiety-prone males who use cannabis under “marked distress” are particularly at risk. Derealisation symptoms may also be experienced after playing video games, particularly after using virtual-reality headsets. A study of 40 participants found that those who used VR headsets while playing the game Skyrim reported significantly more derealisation symptoms than those who played on a PC. Researchers hypothesised that using VR headsets, as opposed to the PC, induced “stronger levels of realness towards the newly experienced virtual world, which casts into doubt the so far experienced ordinary world." Interoceptive exposure exercises have been used in research settings as a means to induce derealization, as well as the related phenomenon depersonalization, in people who are sensitive to high levels of anxiety. Exercises with documented successes include timed intervals of hyperventilation or staring at a mirror, dot, or spiral.


Treatment

In the past, treatments like anticonvulsants, stimulants, and electroconvulsive therapy were tested, but were not effective in reducing symptoms. There is evidence to suggest that cognitive behavioural therapy is effective in treating derealisation symptoms, especially through cognitive reappraisal of catastrophizing thoughts, reducing avoidance behavior, and self-observation. Therapy has been shown to reduce the severity of chronic derealisation and other comorbidities, like anxiety and depression, in the long-term. Currently, chronic derealisation is generally treated using medication. These drugs include antidepressants, antiepileptics, and antipsychotics. Serotonin reuptake blockers (SSRIs) may be prescribed. They mediate serotonergic dysregulation, which is when the body does not have enough serotonin, thought to be a possible cause of derealisation-depersonalisation disorder.


See also


References

{{Authority control Neurology Dissociative disorders Symptoms or signs involving perceptual disturbance