Dehydrocorybulbine (DHCB) is an

alkaloid Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large varie ...

isolated from ''

Corydalis yanhusuo ''Corydalis yanhusuo'' is a plant species in the genus ''Corydalis''. The Chinese name for ''Corydalis yanhusuo'' is ''yan hu suo'' (). The Japanese common name is engosaku (エンゴサク) and the Korean common name is hyeonhosaek (현호색). ...

''. Dehydrocorybulbine binds to the

dopamine D1 receptor Dopamine receptor D1, also known as DRD1. It is one of the two types of D1-like receptor family receptors D1 and D5. It is a protein that in humans is encoded by the DRD1 gene. Tissue distribution D1 receptors are the most abundant kind of ...

. Research has indicated that DHCB can be helpful in reducing

neuropathic pain Neuropathic pain is pain caused by a lesion or disease of the somatosensory nervous system. Neuropathic pain may be associated with abnormal sensations called dysesthesia or pain from normally non-painful stimuli (allodynia). It may have continuo ...

.A Novel Analgesic Isolated from a Traditional Chinese Medicine. ''Current Biology''. Volume 24, Issue 2, p117–123, 20 January 2014
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References

Isoquinoline alkaloids Heterocyclic compounds with 4 rings Methoxy compounds Tetrahydroisoquinoline alkaloids {{alkaloid-stub