CC, for " CopyCat" ''or'' " Carbon Copy" (December 22, 2001 – March 3, 2020), was a brown

tabby A tabby is any domestic cat (''Felis catus'') with a distinctive 'M'-shaped marking on its forehead; stripes by its eyes and across its cheeks, along its back, and around its legs and tail; and (differing by tabby type), characteristic striped, d ...

and white domestic shorthair and the first

cloned Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, ...

pet A pet, or companion animal, is an animal kept primarily for a person's company or entertainment rather than as a working animal, livestock, or a laboratory animal. Popular pets are often considered to have attractive appearances, intelligence, ...

. She was cloned by scientists at

Texas A&M University Texas A&M University (Texas A&M, A&M, or TAMU) is a public university, public, Land-grant university, land-grant, research university in College Station, Texas. It was founded in 1876 and became the flagship institution of the Texas A&M Unive ...

in conjunction with Genetic Savings & Clone Inc. CC's surrogate mother was a tabby, but her genetic donor, Rainbow, was a

calico Calico (; in British usage since 1505) is a heavy plain-woven textile made from unbleached, and often not fully processed, cotton. It may also contain unseparated husk parts. The fabric is far coarser than muslin, but less coarse and thick tha ...

domestic shorthair. The difference in hair coloration between CC and Rainbow is due to X-inactivation and

epigenetic In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "o ...

re-programming, which normally occurs in a

fertilized Fertilisation or fertilization (see spelling differences), also known as generative fertilisation, syngamy and impregnation, is the fusion of gametes to give rise to a new individual organism or offspring and initiate its development. Proc ...

embryo before implantation. In September 2006, CC gave birth to four kittens. The litter was fathered naturally by another lab cat named Smokey. It included two males named Tim and Zip and one female named Tess. Another kitten (a female) was stillborn. This incident was the first time a cloned pet gave birth. Throughout her life, CC appeared to be free of the cloning-related health problems that have arisen in some other animal clones. "CC has always been a perfectly normal cat and her kittens are just that way, too," according to Shirley Kraemer, CC's owner. "We've been monitoring their health and all of them are fine, just like CC has been for the past five years." In 2004, Genetic Savings and Clone produced the first commercially cloned pet, a

Maine Coon The Maine Coon is a large domesticated cat breed. It is one of the oldest natural breeds in North America. The breed originated in the U.S. state of Maine, where it is the official state cat. The breed was popular in cat shows in the late 19th ...

cat named "

Little Nicky ''Little Nicky'' is a 2000 American fantasy comedy film directed by Steven Brill, written by Brill, Adam Sandler, and Tim Herlihy, and starring Sandler in the title role, Patricia Arquette, Harvey Keitel, Rhys Ifans, Tommy "Tiny" Lister Jr., an ...

" who was cloned from a 17-year-old deceased pet cat. On March 3, 2020, CC died at 18 in College Station, Texas.

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Grown
Rainbow (left) and daughter
Copy Cat now has three kittens, September 2006

2001 in science Cloned cats 2001 animal births 2020 animal deaths

See also

References

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