Coumaphos is a nonvolatile, fat-soluble phosphorothioate with ectoparasiticide properties: it kills

insects Insects (from Latin ') are pancrustacean hexapod invertebrates of the class Insecta. They are the largest group within the arthropod phylum. Insects have a chitinous exoskeleton, a three-part body (head, thorax and abdomen), three pairs ...

and mites. It is well known by a variety of brand names as a dip or wash, used on farm and domestic animals to control ticks, mites, flies and fleas. It is also used to control ''Varroa'' mites in

honey bee A honey bee (also spelled honeybee) is a eusocial flying insect within the genus ''Apis'' of the bee clade, all native to Afro-Eurasia. After bees spread naturally throughout Africa and Eurasia, humans became responsible for the current cosmop ...

colonies, though in many areas it is falling out of favor as the mites develop

resistance Resistance may refer to: Arts, entertainment, and media Comics * Either of two similarly named but otherwise unrelated comic book series, both published by Wildstorm: ** ''Resistance'' (comics), based on the video game of the same title ** ''T ...

and as the residual toxicity effects are becoming better understood. In Australia, its registration as suited to home

veterinary Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in animals. Along with this, it deals with animal rearing, husbandry, breeding, research on nutri ...

use was cancelled by the

Australian Pesticides and Veterinary Medicines Authority The Australian Pesticides and Veterinary Medicines Authority (APVMA) is the Australian Government statutory agency responsible for the management and regulation of all agricultural and veterinary chemical products in Australia. History The APVMA ...

in June 2004 after the manufacturer failed to show it was safe for use on pets. The compound has been linked to neurological problems in bees, and may be a factor in colony collapse. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S.

Emergency Planning and Community Right-to-Know Act The Emergency Planning and Community Right-to-Know Act of 1986 is a United States federal law passed by the 99th United States Congress located at Title 42, Chapter 116 of the U.S. Code, concerned with emergency response preparedness. On Octo ...

(42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

References

External links

Coumaphos
US Environmental Protection Agency Acetylcholinesterase inhibitors Organophosphate insecticides Coumarin drugs Chloroarenes Organothiophosphate esters {{antiinfective-drug-stub