Cooperative Synapse Formation
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Cooperative synapse formation describes the mutual amplification of
synapses In the nervous system, a synapse is a structure that allows a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or a target effector cell. Synapses can be classified as either chemical or electrical, depending o ...
. It is needed to explain the distribution of the number of synapses between neurons for example in a rat
cortex Cortex or cortical may refer to: Biology * Cortex (anatomy), the outermost layer of an organ ** Cerebral cortex, the outer layer of the vertebrate cerebrum, part of which is the ''forebrain'' *** Motor cortex, the regions of the cerebral cortex i ...
. Spike-Timing dependence of structural plasticity is capable of explaining the emergence of cooperative synapse formation.Moritz Deger, Moritz Helias, Stefan Rotter, Markus Diesmann: ''Spike-Timing Dependence of Structural Plasticity Explains Cooperative Synapse Formation in the Neocortex'', DOI: 10.1371/journal.pcbi.1002689


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Neurology {{med-stub