Human concentrative nucleoside transporters include

SLC28A1 Concentrative nucleoside transporter 1 (CNT1) is a protein that in humans is encoded by the ''SLC28A1'' gene. See also * Concentrative nucleoside transporters * Nucleoside transporter Nucleoside transporters (NTs) are a group of membrane tra ...

SLC28A2 Concentrative nucleoside transporter 2 (CNT2) is a protein that in humans is encoded by the ''SLC28A2'' gene. See also * Concentrative nucleoside transporters * Nucleoside transporter Nucleoside transporters (NTs) are a group of membrane t ...

and

SLC28A3 SLC may refer to: Places * Salt Lake City, Utah * Salt Lake City International Airport, IATA Airport Code Education * Sarah Lawrence College, NY * School Leaving Certificate (Nepal) * St. Lawrence College, Ontario, Canada * Small Learning C ...

proteins. SLC28A2 is a purine-specific Na⁺-nucleoside cotransporter localised to the

bile Bile (from Latin ''bilis''), or gall, is a dark-green-to-yellowish-brown fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine. In humans, bile is produced continuously by the liver (liver bile ...

canalicular membrane. SLC28A1 is a Na⁺-dependent nucleoside

transporter Transporter may refer to: * Transporter (vehicles), types of vehicles designed to transport items * Transporter wagon, a railway car designed to carry another railway car * Volkswagen Transporter, a model of van * Transporter bridge, a bridge wh ...

selective for

pyrimidine Pyrimidine (; ) is an aromatic, heterocyclic, organic compound similar to pyridine (). One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has nitrogen atoms at positions 1 and 3 in the ring. The other ...

nucleosides and

adenosine Adenosine ( symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9-glycosidic bond. Adenosine is one of the four nucleoside building ...

. It also transports the anti-viral nucleoside analogues Zidovudine and Zalcitabine.

References

{{InterPro content, IPR011657 Protein families Transmembrane transporters