combretastatin
Combretastatin is a dihydrostilbenoid found in '' Combretum caffrum''.
As a class
Combretastatins are a class of natural phenols. A variety of different natural combretastatin molecules are present in the bark of '' Combretum caffrum'', commonl ...
Combretum caffrum
''Combretum caffrum'' is the Eastern Cape South African bushwillow tree.
Biochemistry
In ''C. caffrum'', combretastatins A-1, A-4 and B-1 can be found.Combretum kraussii'', the forest bushwillow.Uteroactive constituents from Combretum kraussii. Bridget K Brookes, Olga V Doudoukina, Lynn C Katsoulis and Joy H D Veale, South African Journal of Chemistry, Dec 99, Vol. 52, Issue 4, page 127 abstract
It can be produced by selective hydrogenation of Combretastatin A-1.
It is a potent inhibitor of microtubule assembly in vitro.