CollecTF is a database of
transcription factor binding sites in the Bacteria domain.
CollecTF compiles ''only'' experimentally validated TF-binding sites. This is accomplished through the manual curation of peer-reviewed literature with a special focus on the experimental process used to identify TF-binding sites.
CollecTF entries are periodically submitted to
NCBI for integration into
RefSeq complete genome records as link-out features, maximizing the visibility of the data and enriching the annotation of RefSeq files with regulatory information. Seeking to facilitate
comparative genomics
Comparative genomics is a field of biological research in which the genomic features of different organisms are compared. The genomic features may include the DNA sequence, genes, gene order, regulatory sequences, and other genomic structural lan ...
and machine-learning analyses of regulatory interactions, in its initial release CollecTF provides domain-wide coverage of two TF families (
LexA and
Fur), as well as extensive representation for a clinically important bacterial family, the
Vibrionaceae.
References
{{reflist
External links
* http://collectf.umbc.edu
Biological databases