Colfosceril palmitate (trade name Exosurf) is a
drug
A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via insufflation (medicine), inhalation, drug i ...
used as a
pulmonary surfactant
Pulmonary surfactant is a surface-active complex of phospholipids and proteins formed by Type II cells, type II alveolar cells. The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions. By adsorption, adso ...
.
It is a drug that is used in surfactant deficient conditions such as
infant respiratory distress syndrome
Infant respiratory distress syndrome (IRDS), also known as surfactant deficiency disorder (SDD), and previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of pulmonary surfacta ...
in newborns.
See also
*
Dipalmitoylphosphatidylcholine
Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid (and a lecithin) consisting of two C16 palmitic acid groups attached to a phosphatidylcholine head-group.
It is the main constituent of pulmonary surfactants, which reduces the work of breath ...
References
Palmitate esters
Phosphate esters
{{respiratory-system-drug-stub