Colforsin daropate is a cardiovascular drug used to treat acute heart failure. Chemically, it is a carboxylic ester derived from the

condensation Condensation is the change of the state of matter from the gas phase into the liquid phase, and is the reverse of vaporization. The word most often refers to the water cycle. It can also be defined as the change in the state of water vapor ...

forskolin Forskolin (coleonol) is a labdane diterpene produced by the plant '' Coleus barbatus'' (blue spur flower). Other names include pashanabhedi, Indian coleus, makandi, HL-362, mao hou qiao rui hua. As with other members of the large diterpene class o ...

(colforsin) with ''N'',''N''-dimethyl-β-alanine. Its water-soluble hydrochloride salt (NKH 477) is an

adenylyl cyclase Adenylate cyclase (EC 4.6.1.1, also commonly known as adenyl cyclase and adenylyl cyclase, abbreviated AC) is an enzyme with systematic name ATP diphosphate-lyase (cyclizing; 3′,5′-cyclic-AMP-forming). It catalyzes the following reaction: :A ...

activator which has been studied for its cardiac selectivity. Colforsin daropate has been studied for its potential to be repurposed for the treatment of some types of cancer.

References

{{Xenobiotic-sensing receptor modulators Acetate esters Vinyl compounds