The Cochrane Library (named after
Archie Cochrane) is a collection of
database
In computing, a database is an organized collection of data or a type of data store based on the use of a database management system (DBMS), the software that interacts with end users, applications, and the database itself to capture and a ...
s in medicine and other
healthcare
Health care, or healthcare, is the improvement or maintenance of health via the preventive healthcare, prevention, diagnosis, therapy, treatment, wikt:amelioration, amelioration or cure of disease, illness, injury, and other disability, physic ...
specialties provided by
Cochrane and other organizations. At its core is the collection of Cochrane Reviews, a database of
systematic review
A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. A systematic review extracts and interprets data from published studies on ...
s and
meta-analyses
Meta-analysis is a method of synthesis of quantitative data from multiple independent studies addressing a common research question. An important part of this method involves computing a combined effect size across all of the studies. As such, th ...
that summarize and interpret the results of medical research. The Cochrane Library aims to make the results of well-conducted
clinical trial
Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel v ...
s readily available and is a key resource in
evidence-based medicine
Evidence-based medicine (EBM) is "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients. It means integrating individual clinical expertise with the best available exte ...
.
Access and use
The Cochrane Library is a subscription-based database, published initially by Update Software and now published by John Wiley & Sons, Ltd. as part of Wiley Online Library. In many countries, including parts of Canada, the United Kingdom, Ireland, the Scandinavian countries, New Zealand, Australia, India, South Africa, and Poland, it has been made available free to all residents by "national provision" (typically a government or Department of Health pays for the license). There are also arrangements for free access in much of Latin America and in "low-income countries", typically via
HINARI. All countries have free access to two-page abstracts of all Cochrane Reviews and short plain-language summaries of selected articles.
Cochrane Reviews appear to be relatively underused in the United States for two reasons:
1) Public access to the Cochrane Library in the United States is limited (the state of
Wyoming
Wyoming ( ) is a landlocked U.S. state, state in the Mountain states, Mountain West subregion of the Western United States, Western United States. It borders Montana to the north and northwest, South Dakota and Nebraska to the east, Idaho t ...
is an exception, having paid for a license to enable free access to Cochrane Reviews for all residents of Wyoming).
2) The government-funded
U.S. National Library of Medicine maintains an alternative database
MEDLINE
MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medic ...
, which is free of charge to everyone and has significantly more extensive coverage than Cochrane.
From 26 March to 26 May 2020, the Cochrane Library provided temporary unrestricted access to everyone in every country in response to the
COVID-19 pandemic
The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December ...
.
Contents
The Cochrane Library consists of the following databases after significant changes in 2018:
* The Cochrane Database of Systematic Reviews (Cochrane Reviews). Contains all the peer-reviewed systematic reviews and protocols (Cochrane Protocols) prepared by the Cochrane Review Groups.
* The Cochrane Central Register of Controlled Trials (CENTRAL). CENTRAL is a database that contains details of articles of controlled trials and other studies of healthcare interventions from bibliographic databases (majorly MEDLINE and EMBASE), and other published and unpublished sources that are difficult to access, including trials from the trial registries such as
International Clinical Trials Registry Platform
The International Clinical Trials Registry Platform (ICTRP) is a platform for the registration of clinical trials operated by the World Health Organization.
The ICTRP combines data from multiple cooperating clinical trials registries to generate ...
(ICTRP) and
ClinicalTrials.gov
ClinicalTrials.gov is a clinical trials registry, registry of clinical trials. It is run by the United States National Library of Medicine (NLM) at the National Institutes of Health, and holds registrations from over 444,000 trials from 221 cou ...
. However, systematic reviewers need to search not only CENTRAL but also ICTRP and
ClinicalTrials.gov
ClinicalTrials.gov is a clinical trials registry, registry of clinical trials. It is run by the United States National Library of Medicine (NLM) at the National Institutes of Health, and holds registrations from over 444,000 trials from 221 cou ...
to identify unpublished studies.
* Cochrane Clinical Answers. These evidence summaries on a variety of questions of interest to healthcare professionals have a user-friendly presentation with graphics and high-level conclusions of the research evidence based on Cochrane Reviews.
The Cochrane Library now also features results from Special Collections and Editorials as well as an option to link out to other reviews compiled b
Epistemonikos
The Cochrane Database of Systematic Reviews, Cochrane Protocols, and CENTRAL are produced by
Cochrane.
''The Cochrane Database of Systematic Reviews''
The Cochrane reviews take the format of full-length methodological studies. Cochrane researchers will perform searches of medical and health databases including
MEDLINE
MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medic ...
/
PubMed
PubMed is an openly accessible, free database which includes primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institute ...
,
EMBASE,
PsycINFO,
CINAHL
CINAHL (Cumulative Index to Nursing and Allied Health Literature) is an index of English-language and selected other-language journal articles about nursing, allied health, biomedicine and healthcare.
Ella Crandall, Mildred Grandbois, and M ...
, etc.; a continually updated database of trials called the Cochrane Central Register of Controlled Trials (CENTRAL); hand searching, where researchers look through entire libraries of
scientific journal
In academic publishing, a scientific journal is a periodical publication designed to further the progress of science by disseminating new research findings to the scientific community. These journals serve as a platform for researchers, schola ...
s by hand and; reference checking of obtained articles in order to identify additional studies that are relevant to the question they are attempting to answer. The quality of each study is carefully assessed using predefined criteria and evidence of weak methodology or the possibility that a study may have been affected by bias is reported in the review.
Cochrane researchers then apply
statistical analysis
Statistical inference is the process of using data analysis to infer properties of an underlying probability distribution.Upton, G., Cook, I. (2008) ''Oxford Dictionary of Statistics'', OUP. . Inferential statistical analysis infers properties of ...
to compare the data of the trials. This creates a review of studies, or
systematic review
A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. A systematic review extracts and interprets data from published studies on ...
, giving a comprehensive view of the efficacy of a particular medical intervention. Finished reviews are available as a full report with diagrams, in condensed form or as a plain language summary, in order to provide for every reader of the review.
Abstracting and indexing
According to ''
Journal Citation Reports
''Journal Citation Reports'' (''JCR'') is an annual publication by Clarivate. It has been integrated with the Web of Science and is accessed from the Web of Science Core Collection. It provides information about academic journals in the natur ...
'', ''The Cochrane Database of Systematic Reviews'' has a 2021
impact factor
The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field.
The Impact Factor of a journa ...
of 11.874, ranking 20th of 172 journals in the Medicine, General and Internal category, down from 11th in 2020 (167 journals). Reviews are
abstracted and indexed in the following
bibliographic databases
A bibliographic database is a database of bibliographic records. This is an organised online collection of references to published written works like journal and newspaper articles, conference proceedings, reports, government and legal publicati ...
:
Science Citation Index Expanded
The Science Citation Index Expanded (SCIE) is a citation index owned by Clarivate and previously by Thomson Reuters.
It was created by the Eugene Garfield at the Institute for Scientific Information, launched in 1964 as Science Citation Index ( ...
,
Scopus
Scopus is a scientific abstract and citation database, launched by the academic publisher Elsevier as a competitor to older Web of Science in 2004. The ensuing competition between the two databases has been characterized as "intense" and is c ...
,
CINAHL
CINAHL (Cumulative Index to Nursing and Allied Health Literature) is an index of English-language and selected other-language journal articles about nursing, allied health, biomedicine and healthcare.
Ella Crandall, Mildred Grandbois, and M ...
,
EMBASE,
MEDLINE
MEDLINE (Medical Literature Analysis and Retrieval System Online, or MEDLARS Online) is a bibliographic database of life sciences and biomedical information. It includes bibliographic information for articles from academic journals covering medic ...
.
Academic comments
The Cochrane Library Feedback tool allows users to provide comments on and feedback of Cochrane Reviews and Protocols in The Cochrane Library. If accepted, the feedback will be published in a scrolling list of comments in reverse chronological order, with the most recent submission at the top of the page. The Collaboration has a procedure for the event of serious error, an event which has only occurred once in its history.
Supplements
Annual colloquia have been conducted by Cochrane since 1993. From 1994 onwards, Cochrane has maintained a database of posters and presentations of past colloquia. From 2009 onwards, Cochrane published the abstracts of those colloquia as supplements to the ''Cochrane Database of Systematic Reviews''. From 2010 to 2016, an annual newsletter related to Cochrane methodology called ''Cochrane Methods'' (), was published as an annual supplement.
See also
*
List of academic databases and search engines
This page contains a representative list of major databases and search engines useful in an academic setting for finding and accessing articles in academic journals, institutional repository, institutional repositories, archives, or other collecti ...
References
{{reflist
External links
The Cochrane Libraryon Wiley Online
Abstracts and summaries of Cochrane Reviews free access
The Centre for Reviews and Dissemination
Systematic review
Health informatics
Bibliographic databases and indexes
Discipline-oriented digital libraries
Full-text scholarly online databases
British digital libraries
Medical databases in the United Kingdom
it:Cochrane Library