Christian Drosten

Christian Heinrich Maria Drosten (, born 1972) is a German virologist whose field of research broadly concerns RNA-viruses, specifically in the areas of ecology, epidemiology and evolution of novel viruses ''(emergent viruses)''. During the COVID-19 pandemic, Drosten's extensive work on previously described Coronaviruses (MERS-CoV, SARS-CoV) enabled him and his laboratory to notably contribute to the efforts to identify, monitor and manage the spread of SARS-CoV2, which led to his national prominence as an expert on the implications and actions required to combat the illness in Germany.

Early life and education

Drosten was born in Lingen and grew up on a farm in , Emsland. After graduating from the episcopal college in Meppen, Drosten initially studied chemical engineering and biology in Dortmund and Münster. From 1994, he studied medicine at the Johann Wolfgang Goethe University Frankfurt am Main and completed his third state examination in May 2000. He did his doctorate at the Institute for transfusion medicine and immunohaematology of the German Red Cross (DRK) blood donation service Hessen in Frankfurt am Main. His dissertation (Dr. med.) on the establishment of a high-throughput system for testing blood donors was rated .

Career

From June 2000, Drosten worked as an intern in the laboratory group of the physician Herbert Schmitz in the virology department of the Bernhard Nocht Institute for Tropical Medicine (BNITM) in Hamburg, where he headed the laboratory group ''Molecular Diagnostics'' and established a research program for the molecular diagnostics of tropical viral diseases. From 2007, Drosten headed the Institute of Virology at University Hospital Bonn. During this time he worked with Isabella Eckerle, who would go on to lead the department of emerging viruses at the University of Geneva. In 2017, he accepted a call to the Charité in Berlin, where he heads the Institute of Virology.

From 2017 until 2019, Drosten was a member of the German Ministry of Health's International Advisory Board on Global Health, chaired by Ilona Kickbusch. Since 2022, he has been serving on the Technical Advisory Panel of the joint World Bank/World Health Organization Pandemic Fund.

Drosten was nominated by Alliance 90/The Greens as delegate to the Federal Conventions for the purpose of electing the President of Germany in 2022.

Drosten is committed to the transparent distribution of scientific data and therefore, publishes in specialist journals such as ''Eurosurveillance'', where all articles are freely available online.

COVID-19 pandemic

In 2017 Drosten warned that the SARS virus potential needed to be investigated.
On 23 January 2020, Drosten, along with other virologists in Europe and Hong Kong, published a workflow of a real-time PCR (RT-PCR) diagnostic test, which was accepted by the World Health Organization (WHO) and which sent test kits to affected regions.

On 19 February 2020, Drosten, along with 26 other scientists, published the Lancet letter in support of scientists and medical professionals in China fighting the outbreak and condemning theories suggesting that the virus does not have a natural origin, which it referred to as "conspiracy theories."

On 17 March 2020, Drosten was appointed to the European Commission's advisory panel on COVID-19, co-chaired by EC President Ursula von der Leyen and ECHSF Stella Kyriakides.COVID-19: Commission launches European team of scientific experts to strengthen EU coordination and medical response
European Commission, press release of 17 March 2020. On 23 March 2020, ''The Guardian'' described Drosten as "the ermancountry's real face of the coronavirus crisis", and also noted that the ''Süddeutsche Zeitung'' had described Drosten as "the nation's corona-explainer-in-chief". He was a counterpart to Lothar Wieler, head of the State's Robert Koch Institute in Berlin, in consulting to German federal and state authorities. In February 2022 he stated that the "ideal" immunity would be achieved by complete Covid vaccination (with 3 doses) and one or more Covid infections on top of that. In September 2022 he stated that a strong Covid wave would occur before December and that a previously undergone Covid infection does not impede virus replication in the throat after three months and that therefore it likely does not protect against transmission. On 26 December 2022, he considered that the pandemic was over and that the acquired immunity would protect the following summer. Within a day, federal minister of justice Marco Buschmann then called for the Corona protections to be ended, which was criticized by the ''Neue Zürcher Zeitung'' as excessive German deference to authority.

During the COVID-19 pandemic, Drosten had a strained relationship with the German tabloid newspaper Bild that culminated early in summer 2020 with the tabloid's critical article about Drosten's study on Covid infection rates among children.

Other scientific activities

Government agencies

* Centre for International Health Protection (ZIG), Robert Koch Institute (RKI), Member of the Scientific Advisory Board (since 2020)

Miscellaneous activities

* Virchow Prize for Global Health, Member of the council (since 2022)
* Coalition for Epidemic Preparedness Innovations (CEPI), Member of the Scientific Advisory Board (since 2021)
* National Research Platform for Zoonoses, Member of the Internal Advisory Board
* World Health Summit, Member of the Scientific Committee

Editorial boards

* ''Emerging Infectious Diseases'', Member of the Editorial Board
* ''Eurosurveillance'', Member of the Editorial Board
* ''Journal of Virology'', Member of the Editorial Board
* ''One Health Outlook'', Member of the Editorial Board
Drosten was
* ''Journal of Clinical Virology'', Member of the Editorial Board

International agencies

* Scientific Advisory Group for Origins of Novel Pathogens

Research

In 2003, Drosten was one of the co-discoverers of SARS-associated coronavirus (SARS-CoV). Together with , a few days after identification and before the Centers for Disease Control and Prevention (CDC) in Atlanta, he succeeded in developing a diagnostic test for the newly identified virus. Drosten immediately made his findings on SARS available to the scientific community on the internet, even before his article appeared in ''New England Journal of Medicine'' in May 2003. Among others, this was honoured by the journal ''Nature''.

From 2012, the research group led by Drosten also researched the Middle East respiratory syndrome-coronavirus (MERS-CoV).

In mid-January 2020, the coronavirus SARS-CoV-2 yielded to his method. The virus first came to light on 30 December 2019, because Li Wenliang (the Chinese ophthalmologist whistleblower who later died of the virus) forced the Chinese government to broadcast its existence the next day. In early January 2020, the research group led by Drosten, together with Marion Koopmans' group, a RIVM group including , Maria Zambon and others, developed a test that was made available worldwide through the WHO. The whole research was published in the journal Eurosurveillance.

In April 2020, the Drosten research group published "a detailed virological analysis of nine cases of COVID-19 that provides proof of active virus replication in tissues of the upper respiratory tract" in ''Nature''.

During the early months of the course of the COVID-19 pandemic in Germany, Drosten advised politicians and authorities and was invited as an expert in the media, among others in the podcast (English: ''The coronavirus update with Christian Drosten''), initially published daily during the week since 26 February 2020, in Norddeutscher Rundfunk (NDR), the frequency of the podcast having been gradually reduced from April 2020 until becoming weekly from 15 June 2020. Drosten then shared his spot on the Podcast with fellow virologist Sandra Ciesek with either being interviewed by a science journalist of the NDR every two weeks to keep the weekly schedule of the podcast while allowing Drosten more time to focus on his research work. The last Podcasts with Drosten were 29 March 2022 and 12 January 2023.

Recognition

At the end of 2003, Drosten, together with Stephan Günther, was awarded an €8,000 prize by the '' Werner Otto Foundation for the Promotion of Medical Research'' for the identification of the SARS coronavirus and the establishment of a rapid diagnostic test system.

In 2004, Drosten received the GlaxoSmithKline funding award for clinical infectiology, the '' Abbott Diagnostics Award'' of the ''European Society for Clinical Virology'', the '' bioMérieux Diagnostics Award'' from the German Society for Hygiene and Microbiology, and the post-doctoral award for virology from the .

In 2005, Drosten was awarded the "Verdienstkreuz am Bande" (Cross) of the Federal Cross of Merit, 2020 he received the "Verdienstkreuz 1. Klasse" (Officer's Cross) for his civil service in time of COVID-19.

On Google Scholar, Drosten has an h-index of 144 as of May 2024.

Personal life

Drosten lives in Berlin-Prenzlauer Berg and has a son born in 2017. His long-time partner is also a scientist. His hobby is playing the guitar. During the height of the corona crisis, the popular punk band ZSK released a song about his work, which went viral.

References

Further reading

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External links

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{{DEFAULTSORT:Drosten, Christian
20th-century German physicians
Physicians of the Charité
Academic staff of the University of Bonn
1972 births
Living people
People from Lingen
German virologists
Recipients of the Cross of the Order of Merit of the Federal Republic of Germany
Members of the German National Academy of Sciences Leopoldina
COVID-19 pandemic in Germany
COVID-19 researchers