Chicago Tylenol Murders
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The Chicago Tylenol murders were a series of poisoning deaths resulting from drug tampering in the
Chicago metropolitan area The Chicago metropolitan area, also referred to as Chicagoland, is the largest metropolitan statistical area in the U.S. state of Illinois, and the Midwest, containing the City of Chicago along with its surrounding suburbs and satellite cities. ...
in 1982. The victims consumed Tylenol-branded acetaminophen (
paracetamol Paracetamol, or acetaminophen, is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol. Parac ...
) capsules that had been laced with
potassium cyanide Potassium cyanide is a compound with the formula KCN. It is a colorless salt, similar in appearance to sugar, that is highly soluble in water. Most KCN is used in gold mining, organic synthesis, and electroplating. Smaller applications include ...
. At least seven people died in the original poisonings, and there were several more deaths in subsequent
copycat crime A copycat crime is a criminal act that is modeled after or inspired by a previous crime. It notably occurs after exposure to media content depicting said crimes, and/or a live criminal model. According to a study, copycat crime is a social phen ...
s. No suspect has been charged or convicted of the poisonings as of , but
New York City New York, often called New York City (NYC), is the most populous city in the United States, located at the southern tip of New York State on one of the world's largest natural harbors. The city comprises five boroughs, each coextensive w ...
resident James W. Lewis was convicted of
extortion Extortion is the practice of obtaining benefit (e.g., money or goods) through coercion. In most jurisdictions it is likely to constitute a criminal offence. Robbery is the simplest and most common form of extortion, although making unfounded ...
for sending a letter to Tylenol's manufacturer,
Johnson & Johnson Johnson & Johnson (J&J) is an American multinational pharmaceutical, biotechnology, and medical technologies corporation headquartered in New Brunswick, New Jersey, and publicly traded on the New York Stock Exchange. Its common stock is a c ...
, that took responsibility for the deaths and demanded $1 million to stop them. The incidents led to reforms in the packaging of
over-the-counter drug Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid pres ...
s and to federal anti-tampering laws.


Deaths and early public safety efforts

On September 28, 1982, 12-year-old Mary Kellerman was hospitalized after consuming a capsule of Extra-Strength Tylenol; she died the next day. On September 29, six other individuals consumed contaminated Tylenol, including Adam Janus (27), Stanley Janus (25), and Theresa Janus (19), who each took Tylenol from a single bottle. All six—the Januses, Mary McFarland (31), Paula Prince (35), and Mary Reiner (27)—would ultimately die from consuming the pills. Asked to investigate the Januses' deaths, nurse Helen Jensen, Arlington Heights's only public health official, visited the Janus household and discovered a Tylenol bottle with an accompanying receipt indicating it had been purchased the same day. Noticing that there were six pills missing, she turned the bottle over to investigator Nick Pishos and reported her suspicion that it was related to the Januses' deaths. Pishos called Edmund R. Donoghue, deputy chief medical examiner for Cook County, who, suspecting that
cyanide In chemistry, cyanide () is an inorganic chemical compound that contains a functional group. This group, known as the cyano group, consists of a carbon atom triple-bonded to a nitrogen atom. Ionic cyanides contain the cyanide anion . This a ...
may be the culprit, asked Pishos to smell the bottle. When Pishos smelled an almond-like scent, Donoghue asked the county's chief toxicologist, Michael Schaffer, to test the capsules, and Schaffer's team determined that four of the 44 remaining capsules from the Janus' bottle contained nearly three times the fatal amount of cyanide. Authorities held a press conference advising the public not to take Tylenol for the time being. By chance, the bottle of Tylenol that Kellerman used was inventoried by paramedics. Investigators noticed that the Janus bottle and the Kellerman bottle came from the same lot, MC2880, and
Johnson & Johnson Johnson & Johnson (J&J) is an American multinational pharmaceutical, biotechnology, and medical technologies corporation headquartered in New Brunswick, New Jersey, and publicly traded on the New York Stock Exchange. Its common stock is a c ...
issued a recall for all Tylenol from that lot. But when tainted bottles from other lots were discovered (for example, the pills in Mary McFarland's possession were traced to lots 1910 MD and MB 2738), the recall expanded to cover those lots and any bottle of extra-strength capsules (from any lot) purchased in the Chicago area, making it one of the largest pharmaceutical recalls ever. A multi-agency investigation found the tampered pills to have been sold or on the shelves at a variety of stores in the Chicago area, including two different Jewel Foods locations (one in Arlington Heights, one in
Elk Grove Village Elk Grove Village is a village in Cook and DuPage counties in the U.S. state of Illinois. Per the 2020 census, the population was 32,812. Located northwest of Chicago along the Golden Corridor, the Village of Elk Grove Village was incorpor ...
); an Osco Drug store (in Schaumburg); a
Walgreens Walgreens is an American pharmacy store chain. It is the second largest in the United States, behind CVS Pharmacy. As of March 2025, the company operated more than 8,700 stores in the U.S. Walgreens has been the subject of a number of lawsuit ...
and a Dominick's (both in
Chicago Chicago is the List of municipalities in Illinois, most populous city in the U.S. state of Illinois and in the Midwestern United States. With a population of 2,746,388, as of the 2020 United States census, 2020 census, it is the List of Unite ...
); and a Frank's Finer Foods (in Winfield). One bottle had been purchased but, due to an off scent, not yet used by Linda Morgan, wife of Judge Lewis V. Morgan. In an effort to reassure the public, Johnson & Johnson, the manufacturer of Tylenol, distributed warnings to hospitals and distributors and halted Tylenol production and advertising. After other incidents, like
strychnine Strychnine (, , American English, US chiefly ) is a highly toxicity, toxic, colorless, bitter, crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine, when inhaled, swallowed, ...
added to Tylenol bottles in
California California () is a U.S. state, state in the Western United States that lies on the West Coast of the United States, Pacific Coast. It borders Oregon to the north, Nevada and Arizona to the east, and shares Mexico–United States border, an ...
, a nationwide recall of Tylenol products was issued on October 5, 1982; an estimated 31 million bottles were in circulation, with a retail value of over US$100 million (equivalent to $ million in ). The company also advertised in the national media for individuals not to consume any of its products that contained acetaminophen after it was determined that only these capsules had been tampered with. Johnson & Johnson also offered to exchange all Tylenol capsules already purchased by the public for solid tablets.
Customs Customs is an authority or Government agency, agency in a country responsible for collecting tariffs and for controlling International trade, the flow of goods, including animals, transports, personal effects, and hazardous items, into and out ...
at airports outside the U.S. asked visitors if they brought Tylenol medicine with them.


Police investigation

The tainted capsules were found to have been manufactured at two different locations,
Pennsylvania Pennsylvania, officially the Commonwealth of Pennsylvania, is a U.S. state, state spanning the Mid-Atlantic (United States), Mid-Atlantic, Northeastern United States, Northeastern, Appalachian, and Great Lakes region, Great Lakes regions o ...
and
Texas Texas ( , ; or ) is the most populous U.S. state, state in the South Central United States, South Central region of the United States. It borders Louisiana to the east, Arkansas to the northeast, Oklahoma to the north, New Mexico to the we ...
, suggesting that the capsules were tampered with after the product had been placed on store shelves for sale. The police hypothesis was that someone had taken bottles off shelves in local stores of the Chicago area, placed
potassium cyanide Potassium cyanide is a compound with the formula KCN. It is a colorless salt, similar in appearance to sugar, that is highly soluble in water. Most KCN is used in gold mining, organic synthesis, and electroplating. Smaller applications include ...
in some of the capsules, and then placed the packages back on the store shelves to be purchased by unknowing customers. In addition to the five bottles that led to the victims' deaths, a few other contaminated bottles were later discovered in the Chicago area. In early 1983, at the
FBI The Federal Bureau of Investigation (FBI) is the domestic Intelligence agency, intelligence and Security agency, security service of the United States and Federal law enforcement in the United States, its principal federal law enforcement ag ...
's request, ''
Chicago Tribune The ''Chicago Tribune'' is an American daily newspaper based in Chicago, Illinois, United States. Founded in 1847, it was formerly self-styled as the "World's Greatest Newspaper", a slogan from which its once integrated WGN (AM), WGN radio and ...
'' columnist
Bob Greene Robert Bernard Greene Jr. (born March 10, 1947) is an American journalist and author. He worked for 24 years for the ''Chicago Tribune'' newspaper, where he was a columnist. Greene has written books on subjects including Michael Jordan, Alice C ...
published the address and grave location of the first and youngest victim, Mary Kellerman. The story, written with the Kellerman family's consent, was proposed by FBI criminal analyst John Douglas on the theory that the perpetrators might visit the house or gravesite if they were made aware of their locations. Both sites were kept under 24-hour video surveillance for several months, but the killer did not surface. A surveillance photo of Paula Prince purchasing cyanide-tampered Tylenol at a
Walgreens Walgreens is an American pharmacy store chain. It is the second largest in the United States, behind CVS Pharmacy. As of March 2025, the company operated more than 8,700 stores in the U.S. Walgreens has been the subject of a number of lawsuit ...
at 1601 North Wells Street in Chicago was released by the Chicago Police Department. Police believe that a bearded man seen just feet behind Prince may be the killer.


Suspects

During the initial investigations, a man named
James William Lewis James may refer to: People * James (given name) * James (surname) * James (musician), aka Faruq Mahfuz Anam James, (born 1964), Bollywood musician * James, brother of Jesus * King James (disambiguation), various kings named James * Prince James ...
was accused of sending a letter to Johnson & Johnson demanding $1 million to stop the cyanide-induced murders. Upon his arrest, Lewis told authorities how the person behind the attacks may have carried out the killings—by buying Tylenol, adding cyanide to the bottles, and returning them to the store shelves. Lewis was also found to have previously possessed a poisoning book, and, according to a confidential law-enforcement document, his fingerprints were discovered on pages related to cyanide. Lewis denied being responsible for the poisonings, but he admitted to writing the letter, which he said he had worked on for three days. During the trial, his attorneys claimed that Lewis "intended only to focus the attention of the authorities on his wife's former employer." Lewis was convicted of extortion and sentenced to 10 years in prison. In 2007, authorities determined that the letter had an October 1, 1982, postmark, meaning that, if Lewis's three-day timeline was accurate, he would have begun working on the letter prior to the first news reports concerning the poisonings. When confronted with this information, Lewis recanted his timeline. Court documents released in early 2009 "show
Department of Justice A justice ministry, ministry of justice, or department of justice, is a ministry or other government agency in charge of the administration of justice. The ministry or department is often headed by a minister of justice (minister for justice in a ...
investigators concluded Lewis was responsible for the poisonings, despite the fact that they did not have enough evidence to charge him". In January 2010, both Lewis and his wife submitted DNA samples and fingerprints to authorities. Lewis said "if the FBI plays it fair, I have nothing to worry about". The DNA samples did not match any DNA recovered on the bottles. Lewis continued to deny responsibility for the poisonings. Lewis died on July 9, 2023, at age 76. Police also investigated a second man, Roger Arnold, a dock worker at a
Jewel-Osco Jewel-Osco is a regional supermarket chain in the Chicago metropolitan area, headquartered in Itasca, a western suburb. In 2025, the company had 189 stores across northern, central, and western Illinois; eastern Iowa; and portions of northwest ...
in Melrose Park, who told officers that he possessed potassium cyanide. Bar owner Marty Sinclair, whose establishment Arnold frequented, reported Arnold to the police, saying that Arnold had discussed killing people with a white powder and had become increasingly erratic after his marriage had dissolved. Arnold had worked with victim Mary Reiner's father at a warehouse, and Arnold's wife had been treated at a hospital across the street from the store in which Reiner bought her cyanide-laced pills. A copy of ''The Poor Man's James Bond'', which contained instructions on making potassium cyanide, was found in Arnold's home. Arnold was held several times by the police, but never charged. In the summer of 1983, Arnold, mistaking John Stanisha (a random passerby) for Sinclair, shot and killed Stanisha, a computer consultant and father of three, who was leaving a bar with multiple friends. Arnold was convicted of the killing in January 1984 and served 15 years of his 30-year sentence for murder, saying in 1996 from prison: "I killed a man, a perfectly innocent person. I had choices. I could have walked away." He died in June 2008. In 2010, Arnold's body was exhumed (and subsequently reburied) so that his femur could be removed for DNA testing. Arnold's DNA did not match the DNA samples discovered on the bottles.


21st-century investigation efforts

In early January 2009, Illinois authorities renewed the investigation. Federal agents searched the home of
Lewis Lewis may refer to: Names * Lewis (given name), including a list of people with the given name * Lewis (surname), including a list of people with the surname Music * Lewis (musician), Canadian singer * " Lewis (Mistreated)", a song by Radiohe ...
in Cambridge, Massachusetts, and seized a number of items. In Chicago, an FBI spokesman declined to comment but said "we'll have something to release later possibly". In 2010, DNA samples were collected from
Lewis Lewis may refer to: Names * Lewis (given name), including a list of people with the given name * Lewis (surname), including a list of people with the surname Music * Lewis (musician), Canadian singer * " Lewis (Mistreated)", a song by Radiohe ...
and Arnold, whose body was exhumed for that purpose; neither's DNA matched DNA samples found on the tainted bottles. Law-enforcement officials received a number of tips related to the case coinciding with its 25th anniversary. In a written statement, the FBI explained,
This review was prompted, in part, by the recent 25th anniversary of this crime and the resulting publicity. Further, given the many recent advances in forensic technology, it was only natural that a second look be taken at the case and recovered evidence.
On May 19, 2011, the FBI requested DNA samples from "Unabomber"
Ted Kaczynski Theodore John Kaczynski ( ; May 22, 1942 – June 10, 2023), also known as the Unabomber ( ), was an American mathematician and domestic terrorist. He was a mathematics prodigy, but abandoned his academic career in 1969 to pursue a reclusi ...
in connection to the Tylenol murders. Kaczynski denied having ever possessed potassium cyanide. The first four Unabomber crimes happened in Chicago and its suburbs from 1978 to 1980, and Kaczynski's parents had a suburban Chicago home in
Lombard, Illinois Lombard is a village in DuPage County, Illinois, United States, and a suburb of Chicago. The population was 44,476 at the 2020 United States census, 2020 census. History Lombard was originally named "Babcock's Grove", after the Babcock brothers ...
, in 1982, where he stayed occasionally.


Aftermath


Copycats

Hundreds of copycat attacks involving Tylenol, other over-the-counter medications, and other products also took place around the United States immediately following the Chicago deaths. Three more deaths occurred in 1986 from gelatin capsules. 23-year-old Diane Elsroth died in
Yonkers, New York Yonkers () is the List of municipalities in New York, third-most populous city in the U.S. state of New York (state), New York and the most-populous City (New York), city in Westchester County, New York, Westchester County. A centrally locate ...
, after ingesting Extra-Strength Tylenol capsules laced with cyanide.
Excedrin Aspirin/paracetamol/caffeine is a combination drug for the treatment of pain, especially tension headache and migraine. It contains aspirin, a non-steroidal anti-inflammatory drug; paracetamol (acetaminophen), an analgesic; and caffeine, a stim ...
capsules in Washington state were tampered with, resulting in the deaths of Susan Snow and Bruce Nickell from cyanide poisoning and the eventual arrest and conviction of Bruce Nickell's wife,
Stella Nickell Stella Maudine Nickell (née Stephenson; born August 7, 1943) is an American woman who was sentenced to 90 years in prison for product tampering after she poisoned Excedrin capsules with lethal cyanide, resulting in the deaths of her husband, B ...
, for her intentional actions in the crimes connected to both murders. That same year,
Procter & Gamble The Procter & Gamble Company (P&G) is an American multinational consumer goods corporation headquartered in Cincinnati, Ohio. It was founded in 1837 by William Procter and James Gamble. It specializes in a wide range of personal health/con ...
's Encaprin was recalled after a spiking hoax in Chicago and Detroit that resulted in a precipitous sales drop and a withdrawal of the pain reliever from the market. In 1991 in Washington state, Kathleen Daneker and Stanley McWhorter were killed from two cyanide-tainted boxes of
Sudafed Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, like treatment of low ...
, and Jennifer Meling went into a coma from a similar poisoning but recovered shortly thereafter. Jennifer's husband, Joseph Meling, was convicted on numerous charges in a federal
Seattle Seattle ( ) is the most populous city in the U.S. state of Washington and in the Pacific Northwest region of North America. With a population of 780,995 in 2024, it is the 18th-most populous city in the United States. The city is the cou ...
court regarding the deaths of Daneker and McWhorter and the attempted murder of his wife, who was abused during the Melings' marriage. Meling was sentenced to
life imprisonment Life imprisonment is any sentence (law), sentence of imprisonment under which the convicted individual is to remain incarcerated for the rest of their natural life (or until pardoned or commuted to a fixed term). Crimes that result in life impr ...
and lost an appeal for a retrial. In 1986,
University of Texas The University of Texas at Austin (UT Austin, UT, or Texas) is a public research university in Austin, Texas, United States. Founded in 1883, it is the flagship institution of the University of Texas System. With 53,082 students as of fall 2 ...
student Kenneth Faries was found dead in his apartment after succumbing to cyanide poisoning. Tampered
Anacin Anacin is an American brand of analgesic that is manufactured by Prestige Consumer Healthcare. Anacin's active ingredients are aspirin and caffeine. History Anacin was invented by William Milton Knight and was first to be used as stated in the ...
capsules were determined to be the source of the cyanide found in his body. His death was ruled a homicide on May 30, 1986. On June 19, 1986, the AP reported that the Travis County Medical Examiner ruled his death a likely suicide. The FDA determined he obtained the poison from a lab in which he worked.


Johnson & Johnson response

Johnson & Johnson received positive coverage for its handling of the crisis: an article in ''
The Washington Post ''The Washington Post'', locally known as ''The'' ''Post'' and, informally, ''WaPo'' or ''WP'', is an American daily newspaper published in Washington, D.C., the national capital. It is the most widely circulated newspaper in the Washington m ...
'' said, "Johnson & Johnson has effectively demonstrated how a major business ought to handle a disaster". The article further stated that "this is no
Three Mile Island accident The Three Mile Island accident was a partial nuclear meltdown of the Unit 2 reactor (TMI-2) of the Three Mile Island Nuclear Generating Station, located on the Susquehanna River in Londonderry Township, Dauphin County, Pennsylvania, Londonderry T ...
in which the company's response did more damage than the original incident", and applauded the company for being honest with the public. In addition to issuing the recall, the company established relations with the Chicago Police Department, the FBI, and the
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respo ...
. This way it could have a part in searching for the person who laced the capsules and they could help prevent further tampering. While at the time of the scare the company's market share collapsed from 35 percent to 8 percent, it rebounded in less than a year, a move credited to the company's prompt and aggressive reaction. In November, it reintroduced capsules in a new, triple-sealed package, coupled with heavy price promotions. Within several years, Tylenol regained the highest market share for the over-the-counter analgesic in the US. After the recall, Johnson & Johnson subsidiary
McNeil Laboratories McNeil Consumer Healthcare is an American medicals products company belonging to Kenvue consumer health group. It primarily sells fast-moving consumer goods such as Over-the-counter drug, over-the-counter drugs. History The company was founded ...
submitted a claim to its insurance company, Affiliated FM Insurance, for the cost of carrying out the recall, a claim which was later denied. A lawsuit determined that McNeil Laboratories was ultimately not covered because the parent company Johnson & Johnson elected not to buy more expensive recall insurance. McNeil sued again in court, further contending that the language of its excess liability insurance policy covered the recall and recall-related expenses. The court hearing that case rejected a claim of liability, stating that the recall "was not caused by liability for the seven deaths; it was at best merely related to the seven deaths in that they served as notice to the plaintiff that the Tylenol remaining on the shelves was potentially harmful." In 1991, Johnson & Johnson agreed to settle, for an undisclosed sum, all lawsuits against it for the original Chicago area deaths. Robert Kniffin, a spokesman for Johnson & Johnson, stated that "though there is no way we could have anticipated a criminal tampering with our product or prevented it, we wanted to do something for the families and finally get this tragic event behind us." The crisis management response, taught today as a model of corporate public relations, is chiefly credited to public relations executive Harold Burson.


Pharmaceutical changes

The 1982 incident inspired the pharmaceutical, food, and consumer product industries to develop tamper-resistant packaging, such as induction seals and improved quality control methods. Moreover, product tampering was made a federal crime. The new laws resulted in
Stella Nickell Stella Maudine Nickell (née Stephenson; born August 7, 1943) is an American woman who was sentenced to 90 years in prison for product tampering after she poisoned Excedrin capsules with lethal cyanide, resulting in the deaths of her husband, B ...
's conviction in the Excedrin tampering case, for which she was sentenced to 90 years in prison. Additionally, the incident prompted the pharmaceutical industry to move away from capsules, which were easy to contaminate as a foreign substance could be placed inside without obvious signs of tampering. Within the year, the FDA introduced more stringent regulations to avoid product tampering. This led to the eventual replacement of the capsule with the solid "caplet", a tablet made in the shape of a capsule, as a drug delivery form and with the addition of
tamper-evident Tamper-evident describes a device or process that makes unauthorized access to the protected object easily detected. Seals, markings, or other techniques may be tamper indicating. Tampering Tampering involves the deliberate altering or adulterat ...
safety seals to bottles of many sorts.


Halloween 1982

While
poisoned candy Poisoned candy myths are mostly urban legends about malevolent strangers intentionally hiding poisons, drugs, or sharp objects such as razor blades in candy, which they then distribute with the intent of harming random children, especially during ...
being given to trick-or-treaters at
Halloween Halloween, or Hallowe'en (less commonly known as Allhalloween, All Hallows' Eve, or All Saints' Eve), is a celebration geography of Halloween, observed in many countries on 31 October, the eve of the Western Christianity, Western Christian f ...
has never been documented, the Tylenol incident, which unfolded across October 1982, raised renewed fears of it. Some communities discouraged trick-or-treating for Halloween, and American grocery stores reported that candy sales were down more than 20%.


See also

* List of multiple homicides in Illinois *
List of serial killers by country This is a list of notable serial killers, by the country where most of the killings occurred. Convicted serial killers by country Afghanistan * Abul Djabar: killed 65 men and boys by strangling them with turbans while raping them; suspected o ...
*
List of unsolved murders These lists of unsolved murders include notable cases where victims were murdered in unknown circumstances. * List of unsolved murders (before 1900) * List of unsolved murders (1900–1979) * List of unsolved murders (1980–1999) * List of unsol ...
*
Paraquat murders The were a series of indiscriminate beverage poisonings carried out in western and central Japan in 1985. The drinks were placed in and around vending machines, where the victim would consume the beverage. All the beverages were poisoned with the ...
* James W. Lewis


References


Further reading

* Bergmann, Joy (November 2, 2000)
"A Bitter Pill – Someone Killed Seven People by Putting Cyanide in Tylenol Capsules – When James Lewis Was Caught for Writing an Extortion Letter, Prosecutors Appeared To Stop Looking for the Killer – Almost 20 Years Later No One Has Been Convicted of the Murders"
''
Chicago Reader The ''Chicago Reader'', or ''Reader'' (stylized as ЯEADER), is an American alternative newspaper in Chicago, Illinois, noted for its literary style of journalism and coverage of the arts, particularly film and theater. The ''Reader'' has been ...
''. Retrieved May 19, 2011. * * Solomon, Michael (July 13, 2022)
"Poison Pill"
''
Medium Medium may refer to: Aircraft *Medium bomber, a class of warplane * Tecma Medium, a French hang glider design Arts, entertainment, and media Films * ''The Medium'' (1921 film), a German silent film * ''The Medium'' (1951 film), a film vers ...
''. Retrieved July 14, 2022.


External links

* {{Portal bar, Chicago, Illinois, Law 1982 in Illinois 1982 murders in the United States 1980s in Chicago Adulteration Mass murder in the United States in the 1980s Deaths by cyanide poisoning Drug safety Health disasters in the United States Johnson & Johnson Mass murder in 1982 Mass poisoning Murder in Chicago 1980s crimes in Illinois Product recalls September 1982 in the United States Unsolved mass murders in the United States Mass murder in Illinois