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The Casoni test is a skin test used in the diagnosis of
hydatid disease Hydatid may refer to: * Echinococcosis * ''Echinococcus granulosus'', known as the hydatid tapeworm * Hydatid of Morgagni * Hydatidiform mole A molar pregnancy also known as a hydatidiform mole, is an abnormal form of pregnancy in which a non-vi ...
. The test involves the intradermal injection of 0.25 ml of sterilised fluid from hydatid cysts/human cyst and sterilised by Seitz filtration on forearm and equal volume of saline injected on the other forearm. Observations made for next 30 mins and after 1 to 2 days. A
wheal response A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of thi ...
occurring at the injection site within 20 minutes is considered positive (immediate hypersensitivity). Delayed hypersensitivity reactions usually read after 18–24 hours. The test is positive in about 90% of cases of hydatid disease affecting the liver, but positive in less than 50% of patients with hydatid disease elsewhere in the body; false positive results are also common. Being a type I hypersensitivity reaction, anaphylactic reaction tray must be kept ready before carrying out the test. Consequently, serological tests are now generally used. The test was described in 1912 by
Tomaso Casoni Tommaso Casoni (1880–1933) was an Italian physician remembered for describing the Casoni test for the diagnosis of hydatid disease. Biography Tommaso Casoni was born on 27 August 1880 in Imola. He studied at the Liceo Torricelli College of F ...
.Casoni T. La diagnosi biologica dell'echinococcosi umana mediante l'introdermoreazione. Folia Clinica Chimica e Microscopica; 1912: 4


References

Skin tests Parasitic diseases {{Med-diagnostic-stub