Calpurnianus is a surname. Notable people with the surname include:
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Decrius Calpurnianus (died 48 AD), Roman Eques
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Marcus Antius Crescens Calpurnianus (), Roman senator
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Marcus Pupius Piso Frugi Calpurnianus
Marcus Pupius Piso Frugi Calpurnianus was a Roman senator. Originally a member of the Calpurnia gens, gens Calpurnia, which claimed descent from Numa Pompilius, the second king of Rome, a Calpurnius Piso Frugi, he was adopted by Marcus Pupius, when ...
(died before 47 BC), Roman senator
{{Surname
Latin-language surnames