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Bernardino Ramazzini (; 4 October 1633 – 5 November 1714) was an Italian physician. Ramazzini, along with Francesco Torti, was an early proponent of the use of cinchona bark (from which
quinine Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to '' Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal le ...
is derived) in the treatment of
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
. His most important contribution to medicine was his book on
occupational disease An occupational disease is any chronic ailment that occurs as a result of work or occupational activity. It is an aspect of occupational safety and health. An occupational disease is typically identified when it is shown that it is more prevale ...
s, ''
De Morbis Artificum Diatriba The De Morbis Artificum Diatriba' (''Dissertation on Workers' Diseases'') is the first book written specifically about occupational diseases and work-related risk prevention. It was written in Latin by Bernardino Ramazzini and published in Moden ...
'' ("Diseases of Workers").


Life

Ramazzini was born in Carpi on 4 October 1633 according to his birth certificate. He studied medicine at the
University of Parma The University of Parma ( it, Università degli Studi di Parma, UNIPR) is a public university in Parma, Emilia-Romagna, Italy. It is organised in nine departments. As of 2016 the University of Parma has about 26,000 students. History During the ...
, where his interest in occupational diseases began.


Career

He was appointed to the chair of theory of medicine at University of Modena in 1682 then served as professor of medicine at the
University of Padua The University of Padua ( it, Università degli Studi di Padova, UNIPD) is an Italian university located in the city of Padua, region of Veneto, northern Italy. The University of Padua was founded in 1222 by a group of students and teachers from ...
from 1700 until his death. He is often called "the father of occupational medicine" The first edition of ''De Morbis'' was published in 1700 in Modena, the second in 1713 in Padua.


Occupational medicine

His book on occupational diseases, ''De Morbis Artificum Diatriba'' (''Diseases of Workers'') outlined the health hazards of chemicals, dust, metals, repetitive or violent motions, odd postures, and other disease-causative agents encountered by workers in more than fifty occupations. This was one of the founding and seminal works of occupational medicine and played a substantial role in its development. A PDF copy of the article. The article contains excerpts from the English translation by
Wilmer Cave Wright Emily Wilmer Cave Wright (, France; January 21, 1868 – November 16, 1951) was a British-born American classical philologist, and a contributor to the culture and history of medicine. She was a professor at Bryn Mawr College, where she taught Gree ...
(Chicago: University of Chicago Press; 1940) based on the Latin text of 1713, and includes a biographical note, ''Bernardino Ramazzini: The Father of Occupational Medicine'', by Giuliano Franco, MD and Francesca Franco MD, MPH
He proposed that physicians should extend the list of questions that
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history o ...
recommended they ask their patients by adding, "What is your occupation?". Ramazzini saw prevention as being better than cure. In his Oratio given in 1711, he suggested that "it is much better to prevent than to cure, and so much easier to foresee future harm and avoid it rather than have to get rid of it after having fallen prey".


Malaria

In regards to
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
, Ramazzini was one of the first to support the use of the quinine-rich bark cinchona. Many falsely claimed that quinine was toxic and ineffective, but Ramazzini recognized its importance. He is quoted, "It uininedid for medicine what gun powder did for war."


Cancer

In 1713, Bernardino Ramazzini said that nuns developed
breast cancer Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a r ...
at a higher rate than married women, because they did not engage in sexual intercourse, and the "unnatural" lack of sexual activity caused instability of the breast tissues that sometimes developed into breast cancer.


Death

Ramazzini died in
Padua Padua ( ; it, Padova ; vec, Pàdova) is a city and ''comune'' in Veneto, northern Italy. Padua is on the river Bacchiglione, west of Venice. It is the capital of the province of Padua. It is also the economic and communications hub of the ...
on 5 November 1714. History (of Occupational Medicine) with notes on the life of Ramazzini.


Acknowledgement

In a lifestyle article "Sitting can lead to an early death," the writer acknowledged Ramazzini's pioneering study of this field in the 17th century.Han, Esther (28 March 2012
Sitting can lead to an early death
'' Sydney Morning Herald''
The honor society Collegium Ramazzini is named after him.


References


Works

* * *


Bibliography

*''Essai sur les Maladies de Disseus.'' Original translation from Latin in "De Mortis Artificum" by M. De Foureau * * * * * * * * *Franco G, Franco F
Bernardino Ramazzini: The Father of Occupational Medicine. Am J Publ Health 2001;91:1380–1382
*Franco G, Fusetti L. A
Bernardino Ramazzini's early observations of the link between musculoskeletal disorders and ergonomic factors. Appl Ergonom 2004;34:67–70
*Franco G. Ramazzini and workers’ voice disorders. Otolaryngol Head Neck Surg 2008;139:329 *Franco G
Work-related musculoskeletal disorders. A lesson from the past. Epidemiology 2010;21:577–579
*Franco G
Health disorders and ergonomic concerns from the use of microscope: A voice from the past. Am J Clin Pathol 2011; 135:170–171
*Franco G
Bernardino Ramazzini and women workers’ health in the second half of the seventeenth century. J Public Health 2012;34:305–308
*Franco G
A tribute to Bernardino Ramazzini (1633–1714) on the tercentenary of his death Occ Med 2014;64:2–4
*Carnevale F, Iavicoli S
Bernardino Ramazzini (1633–1714): a visionary physician, scientist and communicator. Occup Environ Med 2015;72:2–3
*Franco G
La lezione di Bernardino Ramazzini, medico sociale e scienziato visionario. Acc. Naz. Sci Lett. Arti di Modena - Memorie Scientifiche 2015;18:49–62
*Franco G. Prevention is far better than cure - Revisiting the past to strengthen the present: the lesson of Bernardino Ramazzini (1633-1714) in public health. YCP Publisher (2020)
Contents, Preface, Overview


External links


Ramazzini Collegium
The Collegium supplies information on risks and prevention of injury and disease attributable to the workplace and the environment.
Some places and memories related to Ramazzini

Presentations and publications on Ramazzini's famed work "De Morbis Artificum Diatriba"

Celebrazioni del tricentenario della morteBernardino Ramazzini, a pioneer of public health - Presentation given on the occasion of the event “Bernardino Ramazzini, three-centenary from death”. University of Padua, 18 October 2014

Tercentenary of the death''De fontium mutinensium admiranda scaturigine ; tractatus physico-hydro-staticus.''
- full digital facsimile at
Linda Hall Library The Linda Hall Library is a privately endowed American library of science, engineering and technology located in Kansas City, Missouri, sitting "majestically on a urban arboretum." It is the "largest independently funded public library of scien ...
*Franco G
Meglio prevenire che curare – il pensiero di Bernardino Ramazzini, medico sociale e scienziato visionario. Narcissus, 2015
{{DEFAULTSORT:Ramazzini, Bernardino 1633 births 1714 deaths University of Parma alumni University of Modena and Reggio Emilia faculty University of Padua faculty People from Carpi, Emilia-Romagna 17th-century Italian physicians 18th-century Italian physicians Malariologists Italian occupational health practitioners