Busselton Health Study
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__NOTOC__ The Busselton Health Study is a long-term, on-going health
cohort study A cohort study is a particular form of longitudinal study that samples a Cohort (statistics), cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or gra ...
of residents of the Western Australian city of
Busselton Busselton is a city in the South West (Western Australia), South West region of the States and territories of Australia, state of Western Australia approximately south-west of Perth. Busselton has a long history as a popular holiday destin ...
. Over 20,000 Busselton residents have participated in surveys concerning such health topics as
cardiovascular disease Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumati ...
, pulmonary function,
diabetes Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or the cells of th ...
, and
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
, resulting in over 400 publications. The program was initiated by
Kevin Cullen Kevin Cullen (born May 1, 1959) is an American journalist and author. He was a member of ''The Boston Globes 2003 investigative team. ''The Boston Globe'' as an institution won a Pulitzer Prize for ''Public Service'' for coverage of the sexual ...
, a local
general practitioner A general practitioner (GP) is a doctor who is a Consultant (medicine), consultant in general practice. GPs have distinct expertise and experience in providing whole person medical care, whilst managing the complexity, uncertainty and risk ass ...
, and is administered by the Busselton Population Medical Research Institute, which was established in 2000 as the Busselton Population Medical Research Foundation, and the School of Population and Global Health,
University of Western Australia University of Western Australia (UWA) is a public research university in the Australian state of Western Australia. The university's main campus is in Crawley, Western Australia, Crawley, a suburb in the City of Perth local government area. UW ...
. Data from the study was used in a 1996 paper in ''
Nature Nature is an inherent character or constitution, particularly of the Ecosphere (planetary), ecosphere or the universe as a whole. In this general sense nature refers to the Scientific law, laws, elements and phenomenon, phenomena of the physic ...
'' showing some of the first genetic links to asthma, along with a 1999 paper in the ''
New England Journal of Medicine ''The New England Journal of Medicine'' (''NEJM'') is a weekly medical journal published by the Massachusetts Medical Society. Founded in 1812, the journal is among the most prestigious peer-reviewed medical journals. Its 2023 impact factor was ...
'' that was the first to describe the impact of the newly discovered HFE gene causing
HFE hereditary haemochromatosis Hereditary haemochromatosis type 1 (HFE-related haemochromatosis) is a genetic disorder characterized by excessive intestinal absorption of dietary iron, resulting in a pathological increase in total body iron stores. Humans, like most animals, ...
on a population with normal rates of symptoms.


Projects

The Busselton Health Survey has included the following projects: *1966, 1969, 1972, 1975, 1978, and 1981: Cross-sectional comprehensive surveys of all adults on the
Electoral roll An electoral roll (variously called an electoral register, voters roll, voters list, poll book or other description) is a compilation that lists persons who are entitled to vote for particular elections in a particular jurisdiction. The list is ...
(3,400–4,000 participants) *1967, 1970, 1973, 1977, and 1983: Cross-sectional comprehensive surveys of school students (high-school only in 1977, in which there were 556 participants; about 1,600 in all other years) *1987: Cross-sectional comprehensive surveys of all people aged over 65 (1,120 participants) *1990: Cross-sectional respiratory questionnaire of all adults on the electoral roll (3,800 participants) *1992: Family asthma survey (250 families with two parents and two children) *1994–1995: Followup of all participants in cross-sectional surveys from 1966 to 1983 (5,715 participants) *2005–2008: Survey of the changing prevalence of asthma and
Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. GOLD defines COPD as a heterogeneous lung condition characterized by chronic respiratory s ...
(over 2,900 adults and 1,500 children) *2007–present: The Prevalence of Sleep Disordered Breathing *2007–2008: Participated in the international Burden of obstructive lung disease study (more than 600 participants aged over 40) *2008–2010: Busselton Diabetes Study, based on
Fremantle Fremantle () () is a port city in Western Australia located at the mouth of the Swan River (Western Australia), Swan River in the metropolitan area of Perth, the state capital. Fremantle Harbour serves as the port of Perth. The Western Australi ...
Diabetes Study (200 people with diabetes and 200 matched controls *2010–2021: Busselton Healthy Ageing Study (over 5,100 people born between 1946 and 1964) *2019–2023: Busselton Respiratory Study (aiming to recruit over 3,000 adults)


See also

*
Caerphilly Heart Disease Study The Caerphilly Heart Disease Study, also known as the Caerphilly Prospective Study (CaPS), is an epidemiological prospective cohort, set up in 1979 in a representative population sample drawn from Caerphilly, a typical small town in South Wales, ...
* China–Cornell–Oxford Project *
Framingham Heart Study The Framingham Heart Study is a long-term, ongoing cardiovascular cohort study of residents of the city of Framingham, Massachusetts. The study began in 1948 with 5,209 adult subjects from Framingham, and is now on its third generation of partic ...


References


External links

*{{official website, http://bpmri.org.au Busselton 1966 establishments in Australia Epidemiological study projects Cohort studies Australian medical research Health in Western Australia