Brian Wowk
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Brian G. Wowk is a Canadian medical physicist and cryobiologist known for the discovery and development of synthetic
molecules A molecule is a group of two or more atoms that are held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions that satisfy this criterion. In quantum physics, organic chemistry ...
that mimic the activity of natural
antifreeze protein Antifreeze proteins (AFPs) or ice structuring proteins refer to a class of polypeptides produced by certain animals, plants, fungi and bacteria that permit their survival in temperatures below the freezing point of water. AFPs bind to small ...
s in
cryopreservation Cryopreservation or cryoconservation is a process where biological material - cells, tissues, or organs - are frozen to preserve the material for an extended period of time. At low temperatures (typically or using liquid nitrogen) any cell ...
applications, sometimes called "ice blockers". As a senior scientist at 21st Century Medicine, Inc., he was a co-developer with Greg Fahy of key technologies enabling
cryopreservation Cryopreservation or cryoconservation is a process where biological material - cells, tissues, or organs - are frozen to preserve the material for an extended period of time. At low temperatures (typically or using liquid nitrogen) any cell ...
of large and complex tissues, including the first successful
vitrification Vitrification (, via French ') is the full or partial transformation of a substance into a glass, that is to say, a non- crystalline or amorphous solid. Glasses differ from liquids structurally and glasses possess a higher degree of connectivity ...
and transplantation of a
mammal A mammal () is a vertebrate animal of the Class (biology), class Mammalia (). Mammals are characterised by the presence of milk-producing mammary glands for feeding their young, a broad neocortex region of the brain, fur or hair, and three ...
ian
organ Organ and organs may refer to: Biology * Organ (biology), a group of tissues organized to serve a common function * Organ system, a collection of organs that function together to carry out specific functions within the body. Musical instruments ...
(
kidney In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organ (anatomy), organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. They are located on the left and rig ...
). Wowk is also known for early theoretical work on future applications of
molecular nanotechnology Molecular nanotechnology (MNT) is a technology based on the ability to build structures to complex, atomic specifications by means of mechanosynthesis. This is distinct from nanoscale materials. Based on Richard Feynman's vision of miniat ...
, especially
cryonics Cryonics (from ''kryos'', meaning "cold") is the low-temperature freezing (usually at ) and storage of human remains in the hope that resurrection may be possible in the future. Cryonics is regarded with skepticism by the mainstream scien ...
,
nanomedicine Nanomedicine is the medical application of nanotechnology, translating historic nanoscience insights and inventions into practical application. Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to n ...
, and
optics Optics is the branch of physics that studies the behaviour and properties of light, including its interactions with matter and the construction of optical instruments, instruments that use or Photodetector, detect it. Optics usually describes t ...
. In the early 1990s he wrote that
nanotechnology Nanotechnology is the manipulation of matter with at least one dimension sized from 1 to 100 nanometers (nm). At this scale, commonly known as the nanoscale, surface area and quantum mechanical effects become important in describing propertie ...
would revolutionize optics, making possible
virtual reality Virtual reality (VR) is a Simulation, simulated experience that employs 3D near-eye displays and pose tracking to give the user an immersive feel of a virtual world. Applications of virtual reality include entertainment (particularly video gam ...
display systems optically indistinguishable from real scenery as in the fictitious Holodeck of ''
Star Trek ''Star Trek'' is an American science fiction media franchise created by Gene Roddenberry, which began with the Star Trek: The Original Series, series of the same name and became a worldwide Popular culture, pop-culture Cultural influence of ...
''. These systems were described by Wowk in the chapter "Phased Array Optics" in the 1996 anthology ''Nanotechnology: Molecular Speculations on Global Abundance'' , and highlighted in the September 1998 ''Technology Watch'' section of
Popular Mechanics ''Popular Mechanics'' (often abbreviated as ''PM'' or ''PopMech'') is a magazine of popular science and technology, featuring automotive, home, outdoor, electronics, science, do it yourself, and technology topics. Military topics, aviation an ...
magazine.


Early life and education

He obtained his undergraduate and graduate degrees from the
University of Manitoba The University of Manitoba (U of M, UManitoba, or UM) is a public research university in Winnipeg, Manitoba, Canada. Founded in 1877, it is the first university of Western Canada. Both by total student enrolment and campus area, the University of ...
in
Winnipeg Winnipeg () is the capital and largest city of the Provinces and territories of Canada, Canadian province of Manitoba. It is centred on the confluence of the Red River of the North, Red and Assiniboine River, Assiniboine rivers. , Winnipeg h ...
, Canada. Dr. Wowk obtained his PhD in physics in 1997. His graduate studies included work in online portal
imaging Imaging is the representation or reproduction of an object's form; especially a visual representation (i.e., the formation of an image). Imaging technology is the application of materials and methods to create, preserve, or duplicate images. ...
for
radiotherapy Radiation therapy or radiotherapy (RT, RTx, or XRT) is a treatment using ionizing radiation, generally provided as part of cancer therapy to either kill or control the growth of malignant cells. It is normally delivered by a linear particle ...
at the Manitoba Cancer Treatment and Research Foundation (now Cancer Care Manitoba), and work on artifact reduction for
functional magnetic resonance imaging Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area o ...
at the
National Research Council of Canada The National Research Council Canada (NRC; ) is the primary national agency of the Government of Canada dedicated to science and technology research and development. It is the largest federal research and development organization in Canada. Th ...
. His work in the latter field is cited by several text books, including ''Functional MRI'' which includes an image he obtained of
magnetic field A magnetic field (sometimes called B-field) is a physical field that describes the magnetic influence on moving electric charges, electric currents, and magnetic materials. A moving charge in a magnetic field experiences a force perpendicular ...
changes inside the human body caused by respiration.


References


Notes

*
''Nanotechnology: Molecular Speculations on Global Abundance''
*
''Functional MRI''


External links


21st Century Medicine




{{DEFAULTSORT:Wowk, Brian Living people Cryobiology Cryonicists University of Manitoba alumni Medical physicists Year of birth missing (living people)