André Michel Lwoff (8 May 1902 – 30 September 1994) was a French

microbiologist A microbiologist (from Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of microscopic organisms such as bacteria, algae, fungi, and some types of para ...

and

Nobel laureate The Nobel Prizes ( sv, Nobelpriset, no, Nobelprisen) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make o ...

of Russian-Polish origin.

Education, early life and career

Lwoff was born in Ainay-le-Château,

Allier Allier ( , , ; oc, Alèir) is a department in the Auvergne-Rhône-Alpes region that borders Cher to the west, Nièvre to the north, Saône-et-Loire and Loire to the east, Puy-de-Dôme to the south, and Creuse to the south-west. Named after ...

, in

Auvergne Auvergne (; ; oc, label= Occitan, Auvèrnhe or ) is a former administrative region in central France, comprising the four departments of Allier, Puy-de-Dôme, Cantal and Haute-Loire. Since 1 January 2016, it has been part of the new region Au ...

, France, the son of Marie (Siminovitch), an artist, and Solomon Lwoff, a psychiatrist. He joined the Institute Pasteur in Paris when he was 19 years old. In 1932, he finished his PhD and, with the help of a grant from the

Rockefeller Foundation The Rockefeller Foundation is an American private foundation and philanthropy, philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, aft ...

, moved with his wife and co-researcher Marguerite Lwoff to the Kaiser Wilhelm Institute for Medical Research of

Heidelberg Heidelberg (; Palatine German: ') is a city in the German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914, of which roughly a quarter consisted of students ...

Otto Meyerhof Otto Fritz Meyerhof (; April 12, 1884 – October 6, 1951) was a German physician and biochemist who won the 1922 Nobel Prize in Physiology and Medicine. Biography Otto Fritz Meyerhof was born in Hannover, at Theaterplatz 16A (now:Rathenaustrasse ...

, where he did research on the development of

flagellate A flagellate is a cell or organism with one or more whip-like appendages called flagella. The word ''flagellate'' also describes a particular construction (or level of organization) characteristic of many prokaryotes and eukaryotes and thei ...

s. Another Rockefeller grant allowed him go to the

University of Cambridge , mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Schola ...

in 1937. In 1938, he was appointed departmental head at the

Institut Pasteur The Pasteur Institute (french: Institut Pasteur) is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who invented pasteurization and vaccine ...

, where he did groundbreaking research on

bacteriophage A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bac ...

microbiota Microbiota are the range of microorganisms that may be commensal, symbiotic, or pathogenic found in and on all multicellular organisms, including plants. Microbiota include bacteria, archaea, protists, fungi, and viruses, and have been found ...

and on the

poliovirus A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species '' Enterovirus C'', in the family of '' Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of ...

Awards and honors

He was awarded numerous prizes from the French

Académie des Sciences The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French scientific research. It was at ...

, the Grand Prix Charles-Leopold Mayer, the Leeuwenhoek Medal of the

Royal Netherlands Academy of Arts and Sciences The Royal Netherlands Academy of Arts and Sciences ( nl, Koninklijke Nederlandse Akademie van Wetenschappen, abbreviated: KNAW) is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed ...

in 1960 and the Keilin Medal of the British

Biochemical Society The Biochemical Society is a learned society in the United Kingdom in the field of biochemistry, including all the cellular and molecular biosciences. Structure It currently has around 7000 members, two-thirds in the UK. It is affiliated with t ...

in 1964. He was awarded a Nobel Prize in Medicine in 1965 for the discovery of the mechanism that some viruses (which he named

provirus A provirus is a virus genome that is integrated into the DNA of a host cell. In the case of bacterial viruses (bacteriophages), proviruses are often referred to as prophages. However, proviruses are distinctly different from prophages and these te ...

es) use to infect

bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were am ...

. He was an elected member of the United States

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...

, the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, a ...

, and the

American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...

. Throughout his career he partnered with his wife Marguerite Lwoff although he gained considerably more recognition. Lwoff was elected a Foreign Member of the Royal Society (ForMemRS) in 1958. Lwoff was also president of the

FEMS Federation of European Microbiological Societies (FEMS) is an international European scientific organization, formed by the union of a number of national organizations; there are now 57 members from 41 European countries, regular and provisional. ...

for a term of two years from 1974. The FEMS-Lwoff Award in microbiology is named in his honour.

Personal life

Lwoff was married to the microbiologist and virologist Marguerite Lwoff with whom he published many works. He was also a

humanist Humanism is a philosophical stance that emphasizes the individual and social potential and agency of human beings. It considers human beings the starting point for serious moral and philosophical inquiry. The meaning of the term "human ...

against

capital punishment Capital punishment, also known as the death penalty, is the state-sanctioned practice of deliberately killing a person as a punishment for an actual or supposed crime, usually following an authorized, rule-governed process to conclude that ...

References

External links

* {{DEFAULTSORT:Lwoff, Andre Michael 1902 births 1994 deaths Nobel laureates in Physiology or Medicine French Nobel laureates People from Allier Members of the European Molecular Biology Organization French humanists French microbiologists French virologists Phage workers Foreign Members of the Royal Society Members of the French Academy of Sciences Foreign associates of the National Academy of Sciences Leeuwenhoek Medal winners Pasteur Institute Presidents of the International Union of Microbiological Societies Members of the American Philosophical Society