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Avshalom Caspi (born May 5, 1960) is an Israeli-American psychologist and the Edward M. Arnett Professor of Psychology and Neuroscience in the Trinity College of Arts and Sciences at
Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...
, as well as Professor of Personality Development at
King's College London King's College London (informally King's or KCL) is a public research university located in London, England. King's was established by royal charter in 1829 under the patronage of King George IV and the Duke of Wellington. In 1836, King's ...
's Institute of Psychiatry, Psychology and Neuroscience. He is known for his research on mental health and human development, much of which he has conducted with his wife and longtime research partner, Terrie Moffitt. The two first met when they presented adjacent posters at a 1987 conference in St. Louis, Missouri entitled "Deviant Pathways from Childhood to Adulthood". Among Caspi's notable discoveries was that of an association between the
5-HTTLPR 5-HTTLPR (serotonin-transporter-linked promoter region) is a degenerate repeat polymorphic region in ''SLC6A4'', the gene that codes for the serotonin transporter. Since the polymorphism was identified in the middle of the 1990s, it has been exten ...
polymorphism Polymorphism, polymorphic, polymorph, polymorphous, or polymorphy may refer to: Computing * Polymorphism (computer science), the ability in programming to present the same programming interface for differing underlying forms * Ad hoc polymorphis ...
and clinical depression. This discovery, originally reported in a 2003 study, spurred a wave of subsequent research on the potential genetic roots of various psychiatric conditions. However, a 2017 meta-analysis did not support the original finding, nor did a large analysis with nearly 100% power to detect the original finding. Therefore, the general approach of candidate gene or candidate gene by environment interaction research in single small studies is no longer widely accepted. One of the most interesting studies of Avshalom Caspi is his studies about the Monoamine oxidase A gene variation and the risk of antisocial behavior in the presence of childhood abuse as a study of gene and environment interaction, which was further validated by some follow up studies despite some others which did not. He and Moffitt have also collaborated on the
Dunedin Multidisciplinary Health and Development Study The Dunedin Multidisciplinary Health and Development Study  (also known as the Dunedin Study) is a detailed study of human health, development and behaviour. Based at the University of Otago in New Zealand, the Dunedin Study has followed the liv ...
since the 1980s.


Education

Caspi graduated from University of California, Santa Cruz with a B.A. in psychology in 1981. He received his M.A. in 1983 and Ph.D. in 1986 in developmental psychology from Cornell University as part of the Human Development department. His doctoral dissertation was entitled ''Moving against and moving away: Life-course patterns of explosive and withdrawn children''.


Honors and awards

Caspi is a fellow of the
Association for Psychological Science The Association for Psychological Science (APS), previously the American Psychological Society, is an international non-profit organization whose mission is to promote, protect, and advance the interests of scientifically oriented psychology in ...
and the British Academy. He and Moffitt were co-recipients of the 2010
Klaus J. Jacobs Klaus Johann Jacobs (3 December 1936 – 11 September 2008) was a Germany, German-born billionaire in the coffee and chocolate industry, with Switzerland, Swiss citizenship. Biography Early life an education He was born on 3 December 1936 in B ...
Research Prize and Best Practice Award from the Jacobs Foundation, as well as the 2016 APA Award for Distinguished Scientific Contributions to Psychology. In 2013 Caspi was awarded an honorary doctorate from Tilburg University in The Netherlands. In November 2022 Caspi was awarded the Royal Society Te Apārangi's Rutherford Medal, along with the Dunedin Study, team leader Richie Poulton and team members Murray Thomson and Terrie Moffitt.


References


External links

* {{DEFAULTSORT:Caspi, Avshalom 21st-century American psychologists 1960 births Living people Duke University faculty Israeli emigrants to the United States People from Jerusalem University of California, Santa Cruz alumni Cornell University alumni American epidemiologists Academics of King's College London Fellows of the Association for Psychological Science Fellows of the British Academy 20th-century American psychologists