Autologous stem-cell transplantation (also called autogenous, autogeneic, or autogenic stem-cell transplantation and abbreviated auto-SCT) is
autologous transplantation of
stem cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of ...
s—that is, transplantation in which stem cells (
undifferentiated cells from which other cell types develop) are removed from a person, stored, and later given back to that same person.
Although it is most frequently performed with
hematopoietic stem cell
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the very first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta withi ...
s (precursors of blood-forming cells) in
hematopoietic stem cell transplantation
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produ ...
,
cardiac cells have also been used successfully to repair damage caused by heart attacks.
Autologous stem-cell transplantation is distinguished from
allogenic stem cell transplantation where the donor and the recipient of the stem cells are different people.
See also
*
Autologous hematopoietic stem-cell transplantation
*
Stem-cell therapy
References
*
External links
Autologous stem-cell transplantationentry in the public domain NCI Dictionary of Cancer Terms
University of Louisville. "Two years out, patients receiving stem cell therapy show sustained heart function improvement, study suggests." ScienceDaily, 6 Nov. 2012. Web. 6 Nov. 2012.
Transplantation medicine
Stem cells
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