Anhalonine, also known as 1-methyl-6-methoxy-7,8-methylenedioxy-1,2,3,4-tetrahydroisoquinoline, is a
tetrahydroisoquinoline
Tetrahydroisoquinoline (TIQ or THIQ), also known as AMPH-CR, is an organic compound with the chemical formula C9H11N. Classified as a secondary amine, it is derived from isoquinoline by hydrogenation. It is a colorless viscous liquid that is mis ...
alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids.
Alkaloids are produced by a large varie ...
found in ''
Lophophora williamsii
The peyote (; ''Lophophora williamsii'' ) is a small, spineless cactus which contains Psychoactive cactus, psychoactive alkaloids, particularly mescaline. is a Spanish word derived from the Nahuatl (), meaning "caterpillar Pupa#Cocoon, cocoon" ...
'' (peyote) and many other
cactus
A cactus (: cacti, cactuses, or less commonly, cactus) is a member of the plant family Cactaceae (), a family of the order Caryophyllales comprising about 127 genera with some 1,750 known species. The word ''cactus'' derives, through Latin, ...
species.
Peyote contains 3% anhalonine.
It is known to be
pharmacologically active and is said to be similar in its activity to
anhalonidine.
tried anhalonine via
self-experimentation
Self-experimentation refers to single-subject research in which the experimenter conducts the experiment on themself.
Usually this means that a single person is the designer, operator, subject, analyst, and user or reporter of the experiment.
Al ...
at an
oral
The word oral may refer to:
Relating to the mouth
* Relating to the mouth, the first portion of the alimentary canal that primarily receives food and liquid
**Oral administration of medicines
** Oral examination (also known as an oral exam or ora ...
dose of 100mg and found that it was inactive.
Anhalonine was isolated from peyote by
Louis Lewin
Louis Lewin (9 November 1850 - 1 December 1929) was a German pharmacologist. In 1887 he received his first sample of the Peyote, Peyote cactus from Dallas, Texas-based physician John Raleigh Briggs (1851-1907), and later published the first metho ...
in 1888 and was
bioassay
A bioassay is an analytical method to determine the potency or effect of a substance by its effect on animal testing, living animals or plants (''in vivo''), or on living cells or tissues (''in vitro''). A bioassay can be either quantal or quantit ...
ed by Heffter with his report published in 1898.
See also
*
Substituted tetrahydroisoquinoline
A substituted tetrahydroisoquinoline is a tetrahydroisoquinoline with one or more chemical substituents. Many simple tetrahydroisoquinoline alkaloids related to mescaline are known and occur naturally in cactus species such as peyote (''Lophophor ...
*
Lophophorine
Lophophorine, also known as ''N''-methylanhalonine, is a tetrahydroisoquinoline alkaloid made by various cacti in the ''Lophophora'' family. It has been found to lack hallucinogenic effects in humans. Arthur Heffter tried lophophorine at a dose o ...
*
Peyophorine
Peyophorine, also known as ''N''-ethylanhalonine, is a minor substituted tetrahydroisoquinoline, tetrahydroisoquinoline alkaloid found in peyote (''Lophophora williamsii''). It was first described by 1968.
See also
* Substituted tetrahydroisoquin ...
*
Lophophine
Lophophine, also known as 3-methoxy-4,5-methylenedioxyphenethylamine (MMDPEA), is a putative psychedelic and entactogen drug of the methylenedioxyphenethylamine family. It is the α-demethylated homologue of MMDA, and is also closely related t ...
References
External links
Anhalonine - Isomer Design
Methoxyphenethylamines
Methyl compounds
Methylenedioxyphenethylamines
Tetrahydroisoquinoline alkaloids
{{Alkaloid-stub