Andres Metspalu
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Andres Metspalu (born 11 March 1951) is an
Estonian Estonian may refer to: * Something of, from, or related to Estonia, a country in the Baltic region in northern Europe * Estonians, people from Estonia, or of Estonian descent * Estonian language * Estonian cuisine * Estonian culture See also

...
geneticist and member of the
Estonian Academy of Sciences Founded in 1938, the Estonian Academy of Sciences (, ) is Estonia's national academy of science in Tallinn. As with other national academies, it is an independent group of well-known scientists whose stated aim is to promote research and develo ...
.


Biography

Metspalu was born on 11 March 1951 in
Lääne-Viru County Lääne-Viru County ( or ''Lääne-Virumaa'') is one of 15 counties of Estonia. It is in northern Estonia, on the south coast of the Gulf of Finland. In Estonian, ''lääne'' means western and ''ida'' means east or eastern. Lääne-Viru borders Id ...
. In 1969 he graduated from the
Rakke Rakke is a small borough () in Väike-Maarja Parish, Lääne-Viru County, Estonia. Rakke has a population of 1015. Before the 2017 Administrative Reform, Rakke was the administrative centre of Rakke Parish. Notable people * Õnne Kurg (born 19 ...
High School. In 1976 he graduated from the
University of Tartu The University of Tartu (UT; ; ) is a public research university located in the city of Tartu, Estonia. It is the national university of Estonia. It is also the largest and oldest university in the country.
, Faculty of Medicine, as a physician. In 1979 he obtained a Ph.D. in Molecular Biology from the Institute of Molecular Genetics at the
National Academy of Sciences of Ukraine The National Academy of Sciences of Ukraine (NASU; , ; ''NAN Ukrainy'') is a self-governing state-funded organization in Ukraine that is the main center of development of Science and technology in Ukraine, science and technology by coordinatin ...
in
Kiev Kyiv, also Kiev, is the capital and most populous List of cities in Ukraine, city of Ukraine. Located in the north-central part of the country, it straddles both sides of the Dnieper, Dnieper River. As of 1 January 2022, its population was 2, ...
. His thesis was on the structure and function of the
Eukaryotic The eukaryotes ( ) constitute the Domain (biology), domain of Eukaryota or Eukarya, organisms whose Cell (biology), cells have a membrane-bound cell nucleus, nucleus. All animals, plants, Fungus, fungi, seaweeds, and many unicellular organisms ...
ribosome Ribosomes () are molecular machine, macromolecular machines, found within all cell (biology), cells, that perform Translation (biology), biological protein synthesis (messenger RNA translation). Ribosomes link amino acids together in the order s ...
. From 1976 to 1980, Metspalu was a junior scientist at Laboratory of Molecular Biology,
University of Tartu The University of Tartu (UT; ; ) is a public research university located in the city of Tartu, Estonia. It is the national university of Estonia. It is also the largest and oldest university in the country.
. From 1981 to 1982, he was an IREX fellow at
Columbia University Columbia University in the City of New York, commonly referred to as Columbia University, is a Private university, private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Churc ...
. He returned to the Laboratory of Molecular Biology as a Senior Scientist, then from 1985 to 1992 was head of the Laboratory of Gene Expression at Tartu University. From 1986 to 1992, he was Research Director of the Estonian Biocentre. During that period he also visited the
Max Planck Institute for Molecular Genetics The Max Planck Institute for Molecular Genetics is a research institute for molecular genetics based in Berlin, Germany. It is part of the Max Planck Institute network of the Max Planck Society for the Advancement of Science. Departments and re ...
, the
University of Tampere The University of Tampere (UTA) (, ) was a public university in Tampere, Finland that was merged with Tampere University of Technology to create the new Tampere University on 1 January 2019. The university offered undergraduate, postgraduate an ...
, and the
University of Hamburg The University of Hamburg (, also referred to as UHH) is a public university, public research university in Hamburg, Germany. It was founded on 28 March 1919 by combining the previous General Lecture System ('':de:Allgemeines Vorlesungswesen, ...
. In 1992, Metspalu was appointed to the Chair of Biotechnology at the University of Tartu, and head of the Gene Technology Laboratory, Estonian Biocentre. In 1993 he spent three months at the
University of Hamburg The University of Hamburg (, also referred to as UHH) is a public university, public research university in Hamburg, Germany. It was founded on 28 March 1919 by combining the previous General Lecture System ('':de:Allgemeines Vorlesungswesen, ...
's H. Pette Institute for Experimental Immunolog, and then from 1993 to 1994 was a
visiting professor In academia, a visiting scholar, visiting scientist, visiting researcher, visiting fellow, visiting lecturer, or visiting professor is a scholar from an institution who visits a host university to teach, lecture, or perform research on a topic fo ...
at
Baylor College of Medicine The Baylor College of Medicine (BCM) is a private medical school in Houston, Texas, United States. Originally as the Baylor University College of Medicine from 1903 to 1969, the college became independent with the current name and has been se ...
's Dept. of Molecular and Human Genetics with C. Thomas Caskey. From 1996 to 2007, he was again head of the Molecular Diagnostics Centre at Tartu University Clinics. In 1999, he was founder and Chairman of Asper Biotech Ltd. in Tartu. During that period he visited the
International Agency for Research on Cancer The International Agency for Research on Cancer (IARC; ) is an intergovernmental agency forming part of the World Health Organization of the United Nations. Its role is to conduct and coordinate research into the causes of cancer. It also cance ...
(1999-2000) and was founder and Chief Scientific Officer at EGeen International Inc. (
Foster City, California Foster City is a master-planned city located in San Mateo County, California, United States. Foster City is sometimes considered to be part of Silicon Valley for its local industry and its proximity to Silicon Valley cities. There are many n ...
; 2002-2004). Since 2007 he has been Director of the Estonian Genome Center at the University of Tartu.


Research

Metspalu became interested in DNA, genes, and ribosomes in high school, but made his final decision to follow this subject in his fourth semester of molecular biology, when he began practical research in biochemistry under
Artur Lind Artur Lind (6 April 1927, Vändra – 30 November 1989, Tartu) was an Estonian biologist and is considered to be the founder of molecular biology in Estonia. Lind studied to be a surgeon at the University of Tartu. Due to an allergic reaction to ...
. In 1981 Metspalu had the opportunity to work as a research fellow in Columbia and Yale Universities in the United States. On his returning from America, he contributed knowledge to the molecular biology lab at the University of Tartu, which obtained a new generation of devices and began to undertake modern genetic science. Metspalu's major fields of research are genomics and genetic engineering, human genome research methods for large variation in
gene bank A gene bank is a type of biorepository that is used across the world to store the genetic material of animals, plants, and other organisms. It preserves their genetic information in the form of reproductive material like seeds, sperm, eggs, emb ...
s; genetics and complex diseases, the relationship of genes, environmental factors, lifestyle, and state of health between the molecular and genetic analysis in developing the technology of DNA chip technology.


Professional service

Metspalu is active in various research organizations in Estonia and abroad. He is president of the
Estonian Human Genetics Society The Estonian Society of Human Genetics (ESTSHG) (Estonian: ''Eesti Inimesegeneetika Ühing'') is a non-profit organization that promotes research and communication between scientists involved in human and medical genetics. Functions The Estonia ...
and a member of the Steering Committee of the Genomics Center of Excellence, as well as the Human Genetics Society Steering Committee of the
Human Genome Organization The Human Genome Organisation (HUGO) is a non-profit organization founded in 1988. HUGO represents an international coordinating scientific body in response to initiatives such as the Human Genome Project. HUGO has four active committees, includ ...
,
American Society of Human Genetics The American Society of Human Genetics (ASHG), founded in 1948, is a professional membership organization for specialists in human genetics. As of 2009, the organization had approximately 8,000 members. The society's members include researchers, ...
, and ScanBalt Academy.


Awards

On two occasions, Metspalu won the Science Prize (1980, 2003). In 2001 he was awarded the Estonian Red Cross Order of Merit Class III. In 2002 he won the French Award "Prix de la Garantie Medicale et Chirurgicale" and in 2003 was made Chevalier of the "
Ordre des Palmes Académiques A suite, in Western classical music, is an ordered set of instrumental or orchestral/concert band pieces. It originated in the late 14th century as a pairing of dance tunes; and grew in scope so that by the early 17th century it comprised up to ...
". In 2010 he was made an honorary member of
Vilnius University Vilnius University ( Lithuanian: ''Vilniaus universitetas'') is a public research university, which is the first and largest university in Lithuania, as well as one of the oldest and most prominent higher education institutions in Central and Ea ...
, with an honorary doctorate. In 2017, he was awarded the
Baltic Assembly Prize for Science Baltic may refer to: Peoples and languages *Baltic languages, a subfamily of Indo-European languages, including Lithuanian, Latvian and extinct Old Prussian *Balts (or Baltic peoples), ethnic groups speaking the Baltic languages and/or originatin ...
in recognition of "his innovative, diverse and lasting contribution to gene technology and molecular diagnostic".


References


Sources

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External links

{{DEFAULTSORT:Metspalu, Andres 1951 births Estonian geneticists Living people Resigned Communist Party of the Soviet Union members Academic staff of the University of Tartu University of Tartu alumni People from Lääne-Viru County