''Alphanodavirus'' is a genus of non-enveloped

positive-strand RNA virus Positive-strand RNA viruses (+ssRNA viruses) are a group of related viruses that have Sense (molecular biology), positive-sense, single-stranded genomes made of ribonucleic acid. The positive-sense genome can act as messenger RNA (mRNA) and can ...

es in the family '' Nodaviridae''. Insects, mammals, and fishes serve as natural hosts. Diseases associated with this genus include: Nodamura virus paralysis in infected wax moth larvae. Member viruses can also provoke paralysis and death to suckling mice and suckling hamsters. There are five species in this genus.

Structure

Viruses in the genus ''Alphanodavirus'' are non-enveloped, with icosahedral geometries, and T=3 symmetry. The diameter is around 30 nm. Genomes are linear and segmented, bipartite, around 21.4kb in length.

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the

replication model. Positive-strand RNA virus transcription, using the internal initiation model of subgenomic RNA transcription is the method of transcription. Member viruses are released by

lysis Lysis ( ; from Greek 'loosening') is the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic (that is, "lytic" ) mechanisms that compromise its integrity. A fluid containing the contents of lysed cells is called a ...

of the infected host cell. Insects, mammals, and fishes serve as the natural host.

Taxonomy

The genus contains the following species, listed by scientific name and followed by their common names: * ''Alphanodavirus boolarraense'', Boolarra virus * ''Alphanodavirus flockense'', Flock House virus * ''Alphanodavirus heteronychi'', Black beetle virus * ''Alphanodavirus nodamuraense'', Nodamura virus * ''Alphanodavirus pariacotoense'', Pariacoto virus

References

External links

ICTV Report: ''Nodaviridae''

{{Taxonbar, from=Q18819856 Nodaviridae Virus genera