Alexander Pines (; June 22, 1945 – November 1, 2024) was an American chemist. He was the Glenn T. Seaborg Professor Emeritus,

University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California), is a Public university, public Land-grant university, land-grant research university in Berkeley, California, United States. Founded in 1868 and named after t ...

, Chancellor's Professor Emeritus and Professor of the Graduate School, University of California, Berkeley, and a member of the California Institute for Quantitative Biosciences (QB3) and the Department of Bioengineering.

Background

Pines was born on June 22, 1945, and grew up in Bulawayo in

Southern Rhodesia Southern Rhodesia was a self-governing British Crown colony in Southern Africa, established in 1923 and consisting of British South Africa Company (BSAC) territories lying south of the Zambezi River. The region was informally known as South ...

(now Zimbabwe). He studied undergraduate mathematics and chemistry in Israel at

Hebrew University of Jerusalem The Hebrew University of Jerusalem (HUJI; ) is an Israeli public university, public research university based in Jerusalem. Co-founded by Albert Einstein and Chaim Weizmann in July 1918, the public university officially opened on 1 April 1925. ...

. Coming to the United States in 1968, Pines obtained his Ph.D. in chemical physics at M.I.T. in 1972 and joined the UC Berkeley faculty later that year. Pines died on November 1, 2024, at the age of 79.

Research

Pines was a pioneer in the development and applications of

nuclear magnetic resonance Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are disturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a ...

(NMR) spectroscopy of non-liquid samples. In his early work, he demonstrated time-reversal of dipole-dipole couplings in many-body spin systems, and introduced high sensitivity, cross polarization NMR of dilute spins such as

carbon-13 Carbon-13 (13C) is a natural, stable isotope of carbon with a nucleus containing six protons and seven neutrons. As one of the environmental isotopes, it makes up about 1.1% of all natural carbon on Earth. Detection by mass spectrometry A m ...

in solids ( Proton Enhanced Nuclear Induction Spectroscopy), thereby helping to launch the era of modern

solid-state NMR Solid-state nuclear magnetic resonance (ssNMR) is a spectroscopy technique used to characterize atomic-level structure and dynamics in solid materials. ssNMR spectra are broader due to nuclear spin interactions which can be categorized as dipolar ...

in chemistry. He also developed the areas of multiple-quantum

spectroscopy Spectroscopy is the field of study that measures and interprets electromagnetic spectra. In narrower contexts, spectroscopy is the precise study of color as generalized from visible light to all bands of the electromagnetic spectrum. Spectro ...

, adiabatic sech/tanh inversion pulses, zero-field NMR, double rotation and dynamic-angle spinning, iterative maps for pulse sequences and quantum control, and the quantum geometric phase. His combination of optical pumping and cross-polarization made it possible to observe enhanced NMR of surfaces and the selective "lighting up" of solution NMR and

magnetic resonance imaging Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and ...

(MRI) by means of laser-polarized

xenon Xenon is a chemical element; it has symbol Xe and atomic number 54. It is a dense, colorless, odorless noble gas found in Earth's atmosphere in trace amounts. Although generally unreactive, it can undergo a few chemical reactions such as the ...

. Until he retired to emeritus status, his program was composed of two complementary components. The first is the establishment of new concepts and techniques in NMR and MRI, in order to extend their applicability and enhance their capability to investigate molecular structure, organization and function from materials to organisms. Examples of methodologies emanating from these efforts include: novel polarization and detection methods, ex-situ and mobile NMR and MRI, laser-polarized NMR and MRI, functionalized NMR biosensors and molecular imaging, ultralow and zero-field

SQUID A squid (: squid) is a mollusc with an elongated soft body, large eyes, eight cephalopod limb, arms, and two tentacles in the orders Myopsida, Oegopsida, and Bathyteuthida (though many other molluscs within the broader Neocoleoidea are also ...

NMR and MRI, remote detection of NMR and MRI amplified by means of

laser A laser is a device that emits light through a process of optical amplification based on the stimulated emission of electromagnetic radiation. The word ''laser'' originated as an acronym for light amplification by stimulated emission of radi ...

magnetometers A magnetometer is a device that measures magnetic field or magnetic dipole moment. Different types of magnetometers measure the direction, strength, or relative change of a magnetic field at a particular location. A compass is one such device, o ...

, and miniaturization including fluid flow through porous materials and "microfluidic chemistry and NMR/MRI on a chip". The second component of his research program involves the application of such novel methods to problems in chemistry, materials science, and biomedicine.

Awards

Among his many prestigious awards and honors, Pines received the Langmuir Medal of the American Chemical Society, the

Faraday Medal The Faraday Medal is a top international medal awarded by the UK Institution of Engineering and Technology (IET) (previously called the Institution of Electrical Engineers (IEE)). As one of the world's most prestigious awards in engineering, it ...

of the Royal Society of Chemistry, the

Wolf Prize The Wolf Prize is an international award granted in Israel, that has been presented most years since 1978 to living scientists and artists for "achievements in the interest of mankind and friendly relations among people ... irrespective of natio ...

for Chemistry (together with Richard R. Ernst) in 1991. He was awarded the F.A. Cotton Medal for Excellence in Chemical Research of the

American Chemical Society The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all ...

in 1999. In 2005, an Ampere Symposium was held in honor of Pines' 60th birthday in

Chamonix Chamonix-Mont-Blanc (; ; (no longer in use)), more commonly known simply as Chamonix (), is a communes of France, commune in the departments of France, department in the regions of France, region in Southeastern France. It was the site of the f ...

, France, and in 2008, he was awarded the Russell Varian Prize at the European Magnetic Resonance Conference. (Previous Varian Prizes winners: Jean Jeener, Erwin Hahn,

Nicolaas Bloembergen Nicolaas Bloembergen (March 11, 1920 – September 5, 2017) was a Dutch- American physicist and Nobel laureate, recognized for his work in developing driving principles behind nonlinear optics for laser spectroscopy. During his career, he was a ...

, John. S. Waugh, and Alfred G. Redfield.) Pines was also recognized by numerous teaching honors, including the University of California's Distinguished Teaching Award. He was a member of the U.S.

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, NGO, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the ...

, the

American Academy of Arts and Sciences The American Academy of Arts and Sciences (The Academy) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and other ...

and a Foreign Member of the

Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...

(London); he was Doctor Honoris Causa at the

Weizmann Institute of Science The Weizmann Institute of Science ( ''Machon Weizmann LeMada'') is a Public university, public research university in Rehovot, Israel, established in 1934, fourteen years before the State of Israel was founded. Unlike other List of Israeli uni ...

, Universite Paul Cezanne,

University of Paris The University of Paris (), known Metonymy, metonymically as the Sorbonne (), was the leading university in Paris, France, from 1150 to 1970, except for 1793–1806 during the French Revolution. Emerging around 1150 as a corporation associated wit ...

and the University of Rome, and past President of the International Society of Magnetic Resonance.

References

External links

BiographyU.C. Berkeley College of Chemistry faculty pagePines Group WebpageAlex Pines webpage
{{DEFAULTSORT:Pines, Alexander 1945 births 2024 deaths Scientists from Tel Aviv 21st-century American chemists Foreign members of the Royal Society Hebrew University of Jerusalem alumni Israeli chemists Israeli emigrants to the United States Israeli Jews Jewish American scientists Jewish chemists Massachusetts Institute of Technology School of Science alumni Members of the United States National Academy of Sciences Rhodesian Jews UC Berkeley College of Chemistry faculty White Rhodesian people Wolf Prize in Chemistry laureates Nuclear magnetic resonance Fellows of the American Physical Society 21st-century American Jews