Adolph Strecker (October 21, 1822 – November 7, 1871) was a German
chemist who is remembered primarily for his work with
amino acids
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha am ...
.
Life and work
Strecker was born in Darmstadt, the son of Friedrich Ludwig Strecker, an
archivist working for the hessian
Grand Duke
Grand duke (feminine: grand duchess) is a European hereditary title, used either by certain monarchs or by members of certain monarchs' families. In status, a grand duke traditionally ranks in order of precedence below an emperor, as an approxi ...
, and Henriette Amalie Johannette Koch. Adolph Strecker attended school in Darmstadt until 1838 when he changed to the higher Gewerbeschule. After receiving his abitur in 1840, Strecker began studying science at the
University of Giessen, where
Justus Liebig was a professor. In August 1842, Strecker received his PhD and began teaching at a
realschule in Darmstadt. He refused one offer to work for Liebig, but in 1846 he accepted another and became Liebig's private assistant at the University of Giessen. Strecker finished his habilitation in 1848 and became a lecturer at the university.
Strecker investigated a wide variety of problems in both organic and inorganic chemistry during his time at Giessen. Examples include the molecular masses of
silver and
carbon, the reactions of
lactic acid, the decomposition of
hippuric acid by
nitric acid, and the separation of
cobalt and
nickel.
Strecker wanted to leave Giessen for a position at the
University of Berlin, but when he heard of an open position at Norway's
University of Christiania, he applied for it and in 1851 became a professor there. While in Norway, Strecker focused on organic chemistry, covering a broad range of topics from organometallic chemistry to natural products.
Strecker left Norway on
Christian Gottlob Gmelin's death in 1860 to accept the latter's position at the
University of Tübingen. There he conducted research on
guanine,
xanthine,
caffeine, and
theobromine, and on the very toxic
thallium oxides, which damaged his health severely. He moved to the
University of Würzburg in 1870, but his first semester was interrupted by the
Franco-Prussian War of 1870–1871. Strecker became an officer during the war and returned to the university after it, where he started his last semester. In the summer of 1871 he undertook a recreational holiday in
Berchtesgaden
Berchtesgaden () is a municipality in the district Berchtesgadener Land, Bavaria, in southeastern Germany, near the border with Austria, south of Salzburg and southeast of Munich. It lies in the Berchtesgaden Alps, south of Berchtesgaden; the ...
,
Bavaria, but his health began to deteriorate. Strecker died in
Würzburg, where he is buried in the Hauptfriedhof.
Strecker synthesis
The
Strecker synthesis of amino acids involves the reaction of
potassium cyanide
Potassium cyanide is a compound with the formula KCN. This colorless crystalline salt, similar in appearance to sugar, is highly soluble in water. Most KCN is used in gold mining, organic synthesis, and electroplating. Smaller applications includ ...
,
ammonium chloride, and an aldehyde to make an alpha amino acid. The reaction can also be run with ammonia, hydrogen cyanide, and an aldehyde.
Because of the relative simplicity of the reactants, the Strecker synthesis has been invoked by those studying both the origin of life and meteoritic amino acids.
Also named for Strecker are the
Strecker degradation
The Strecker degradation is a chemical reaction which converts an α-amino acid into an aldehyde containing the side chain, by way of an imine intermediate. It is named after Adolph Strecker, a German chemist.
The original observation by Strecker ...
, which involves the conversion of amino acids into imines and then into ketones, and the
Strecker sulfite alkylation.
Notable people who taught Strecker
*
Justus von Liebig
Justus Freiherr von Liebig (12 May 1803 – 20 April 1873) was a German scientist who made major contributions to agricultural and biological chemistry, and is considered one of the principal founders of organic chemistry. As a professor at t ...
(1803–1873)
Notable students of Strecker
*
Georg Zehfuss
Georg may refer to:
* ''Georg'' (film), 1997
*Georg (musical), Estonian musical
* Georg (given name)
* Georg (surname)
* , a Kriegsmarine coastal tanker
See also
* George (disambiguation)
George may refer to:
People
* George (given name)
* ...
(de) (1832–1901)
Family
Strecker, while serving as a professor in Norway, returned to Germany for several holidays. During one such visit to Darmstadt, Strecker, on July 3, 1852, married Karoline Auguste Natalie Weber (1852–1853), who died months later – on October 13, 1853. She had given birth on October 2, 1853, to Friederike Caroline Sophie Christiane Natalie Strecker. Adolph Stecker married a second time on September 29, 1855.
References
External links
Adolph Strecker obituaryby Rudolf Wagner from ''Berichte der Deutschen Chemischen Gesellschaft'', 1872, part V, pp. 125–131
* Obituary in the ''Journal of the Chemical Society'', 1872, volume 25, p. 353
* Adolph Strecker by B. Lepsius (1892), ''Allgemeine Deutsche Biographie'', volume 36, Leipzig: Duncker & Humblot – entry for Strecker
– brief biography and two pictures at Tübingen University
* ''Regnault-Strecker's kurzes Lehrbuch der Chemie''. Vieweg, Braunschweig 185
Digital editionby the
University and State Library Düsseldorf
The University and State Library Düsseldorf (german: Universitäts- und Landesbibliothek Düsseldorf, abbreviated ULB Düsseldorf) is a central service institution of Heinrich Heine University. Along with Bonn and Münster, it is also one of th ...
*
2. Organische Chemie. 1853*
1. Anorganische Chemie. 3., verb. Aufl. 1855*
2. Organische Chemie. 2. Aufl.1857*
1. Anorganische Chemie. 4. Aufl.1858*
1. Anorganische Chemie. 9., neu bearb. Aufl. / von Johannes Wislicenus. 1877
{{DEFAULTSORT:Strecker, Adolph
University of Würzburg faculty
University of Tübingen faculty
19th-century German chemists
University of Giessen alumni
University of Oslo faculty
1822 births
1871 deaths
Scientists from Darmstadt