ATC Code C01
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C01A Cardiac

glycoside In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycoside ...
s


C01AA Digitalis glycosides

:C01AA01 Acetyldigitoxin :C01AA02 Acetyldigoxin :C01AA03 Digitalis leaves :C01AA04 Digitoxin :C01AA05 Digoxin :C01AA06 Lanatoside C :C01AA07 Deslanoside :C01AA08 Metildigoxin :C01AA09
Gitoformate Gitoformate ( INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Produced by Madaus, it is not avai ...
:C01AA52 Acetyldigoxin, combinations


C01AB Scilla glycosides

:C01AB01 Proscillaridin :C01AB51 Proscillaridin, combinations


C01AC Strophanthus glycosides

:C01AC01 G-strophanthin :C01AC03
Cymarin Cymarin (or cymarine) is a cardiac glycoside. Plants of the genus '' Apocynum'', including '' Apocynum cannabinum'' and ''Apocynum venetum'', contain cymarin. Cymarin is a cardiac glycoside and an anti-arrhythmia and cardiotonic A cardiac stimu ...


C01AX Other cardiac glycosides

:C01AX02
Peruvoside Peruvoside (or cannogenin thevetoside) is a cardiac glycoside for heart failure. It is derived from ''Cascabela thevetia ''Cascabela thevetia'' (syn: ''Thevetia peruviana'') is a poisonous plant native throughout Mexico and in Central America, ...


C01B Antiarrhythmics, class I and III


C01BA Antiarrhythmics, class Ia

:C01BA01 Quinidine :C01BA02 Procainamide :C01BA03 Disopyramide :C01BA04 Sparteine :C01BA05
Ajmaline Ajmaline (also known by trade names Gilurytmal, Ritmos, and Aritmina) is an alkaloid that is classified as a 1-A antiarrhythmic agent. It is often used to induce arrhythmic contraction in patients suspected of having Brugada syndrome. Individuals ...
:C01BA08 Prajmaline :C01BA12 Lorajmine :C01BA13 Hydroquinidine :C01BA51 Quinidine, combinations excluding psycholeptics :C01BA71 Quinidine, combinations with psycholeptics


C01BB Antiarrhythmics, class Ib

:C01BB01 Lidocaine :C01BB02 Mexiletine :C01BB03 Tocainide :C01BB04 Aprindine


C01BC Antiarrhythmics, class Ic

:C01BC03 Propafenone :C01BC04 Flecainide :C01BC07
Lorcainide Lorcainide (Lorcainide hydrochloride) is a Class 1c antiarrhythmic agent that is used to help restore normal heart rhythm and conduction in patients with premature ventricular contractions, ventricular tachycardiac and Wolff–Parkinson–White s ...
:C01BC08 Encainide :C01BC09 Ethacizine


C01BD Antiarrhythmics, class III

:C01BD01 Amiodarone :C01BD02
Bretylium tosilate Bretylium (also bretylium tosylate) is an antiarrhythmic agent. It blocks the release of noradrenaline from nerve terminals. In effect, it decreases output from the peripheral sympathetic nervous system. It also acts by blocking K+ channels and ...
:C01BD03
Bunaftine Bunaftine (or bunaphtine) is an antiarrhythmic agent Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a group of pharmaceuticals that are used to suppress abnormally fast rhythms ( tachycardias), such as atrial fibril ...
:C01BD04 Dofetilide :C01BD05 Ibutilide :C01BD06 Tedisamil :C01BD07
Dronedarone Dronedarone, sold under the brand name Multaq, is a medication by Sanofi-Aventis, mainly for the indication of cardiac arrhythmias. It was approved by the FDA on July 2, 2009. It was recommended as an alternative to amiodarone for the treatmen ...


C01BG Other antiarrhythmics, class I and III

:C01BG01 Moracizine :C01BG07
Cibenzoline Cibenzoline (or cifenline) is a Class Ia antiarrhythmic. Pituxate & Ecipramidil are other ''gem A gemstone (also called a fine gem, jewel, precious stone, or semiprecious stone) is a piece of mineral crystal which, in cut and polished fo ...
:C01BG11 Vernakalant


C01C Cardiac stimulants excluding cardiac glycosides


C01CA Adrenergic and

dopaminergic Dopaminergic means "related to dopamine" (literally, "working on dopamine"), dopamine being a common neurotransmitter. Dopaminergic substances or actions increase dopamine-related activity in the brain. Dopaminergic brain pathways facilitate do ...
agents

:C01CA01 Etilefrine :C01CA02 Isoprenaline :C01CA03
Norepinephrine Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as both a hormone and neurotransmitter. The name "noradrenaline" (from Latin '' ad ...
:C01CA04
Dopamine Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. Dopamine constitutes about 8 ...
:C01CA05
Norfenefrine Norfenefrine (INN; also known as ''meta''-octopamine, 3-octopamine, and 3,β-dihydroxyphenethylamine) is an adrenergic agent used as a sympathomimetic drug which is marketed in Europe, Japan, and Mexico. Along with its structural isomer ''p''-oc ...
:C01CA06 Phenylephrine :C01CA07 Dobutamine :C01CA08
Oxedrine Synephrine, or, more specifically, ''p''-synephrine, is an alkaloid, occurring naturally in some plants and animals, and also in approved drugs products as its ''m''-substituted analog known as neo-synephrine. ''p''-Synephrine (or formerly Sympa ...
:C01CA09 Metaraminol :C01CA10
Methoxamine Methoxamine is an α1-adrenergic receptor agonist, somewhat similar in structure to butaxamine and 2,5-DMA. It is no longer marketed. See also * Sertraline * Phenylephrine * Synephrine * Phentolamine * Midodrine Midodrine is a vasopres ...
:C01CA11 Mephentermine :C01CA12 Dimetofrine :C01CA13
Prenalterol Prenalterol is a cardiac stimulant which acts as a β1 adrenoreceptor agonist. Synthesis Stereospecific Prenalterol exhibits adrenergic agonist activity in spite of an interposed oxymethylene group. The stereospecific synthesis devised for th ...
:C01CA14 Dopexamine :C01CA15
Gepefrine 3-Hydroxyamphetamine (INN; trade names Pressionorm, Gepefrine, and Wintonin), also known as meta-hydroxyamphetamine, and α-methyl-''meta''-tyramine, is an antihypotensive or sympathomimetic agent of the amphetamine family that is marketed in c ...
:C01CA16
Ibopamine Ibopamine is a sympathomimetic drug, designed as a prodrug of epinine (deoxyepinephrine or ''N''-methyldopamine), used in ophthalmology. It induces mydriasis. It also has been investigated for use in the treatment of congestive heart failure. I ...
:C01CA17 Midodrine :C01CA18 Octopamine :C01CA19 Fenoldopam :C01CA21
Cafedrine Cafedrine ( INN), also known as norephedrinoethyltheophylline, is a chemical linkage of norephedrine and theophylline and is a cardiac stimulant used to increase blood pressure Blood pressure (BP) is the pressure of circulating blood again ...
:C01CA22 Arbutamine :C01CA23
Theodrenaline Theodrenaline (INN), also known as noradrenalinoethyltheophylline, is a chemical linkage of norepinephrine Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that function ...
:C01CA24 Epinephrine :C01CA25
Amezinium metilsulfate Amezinium metilsulfate ( INN, trade name Regulton) is a sympathomimetic drug used for the treatment of low blood pressure. It has multiple mechanisms, including stimulation of alpha Alpha (uppercase , lowercase ; grc, ἄλφα, ''álpha'', ...
:C01CA26 Ephedrine :C01CA27 Droxidopa :C01CA30 Combinations :C01CA51 Etilefrine, combinations


C01CE Phosphodiesterase inhibitors

:C01CE01 Amrinone :C01CE02 Milrinone :C01CE03 Enoximone :C01CE04 Bucladesine :QC01CE90
Pimobendane Pimobendan ( INN, or pimobendane; tradenames Vetmedin, Acardi) is a veterinary medication. It is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects. Pimobendan is used in t ...


C01CX Other cardiac stimulants

:C01CX06
Angiotensinamide Angiotensinamide (INN; BAN and USAN angiotensin amide) is a potent vasoconstrictor used as a cardiac stimulant. It is a derivative of angiotensin II. See also * Angiotensin Angiotensin is a peptide hormone that causes vasoconstriction and ...
:C01CX07 Xamoterol :C01CX08 Levosimendan :C01CX09
Angiotensin II Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure. It is part of the renin–angiotensin system, which regulates blood pressure. Angiotensin also stimulates the release of aldosterone from the adr ...


C01D Vasodilators used in cardiac diseases


C01DA Organic nitrates

:C01DA02
Glyceryl trinitrate Nitroglycerin (NG), (alternative spelling of nitroglycerine) also known as trinitroglycerin (TNG), nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane, is a dense, colorless, oily, explosive liquid most commonly produced by nitrating g ...
:C01DA04 Methylpropylpropanediol dinitrate :C01DA05
Pentaerithrityl tetranitrate Pentaerythritol tetranitrate (PETN), also known as PENT, PENTA, (ПЕНТА, primarily in Russian) TEN, corpent, or penthrite (or, rarely and primarily in German, as nitropenta), is an explosive material. It is the nitrate ester of pentaeryth ...
:C01DA07
Propatylnitrate Propatylnitrate (propatyl nitrate) is a nitrate. References Nitrate esters {{cardiovascular-drug-stub ...
:C01DA08 Isosorbide dinitrate :C01DA09 Trolnitrate :C01DA13 Eritrityl tetranitrate :C01DA14 Isosorbide mononitrate :C01DA20 Organic nitrates in combination :C01DA38 Tenitramine :C01DA52 Glyceryl trinitrate, combinations :C01DA54 Methylpropylpropanediol dinitrate, combinations :C01DA55 Pentaerithrityl tetranitrate, combinations :C01DA57 Propatylnitrate, combinations :C01DA58 Isosorbide dinitrate, combinations :C01DA59 Trolnitrate, combinations :C01DA63 Eritrityl tetranitrate, combinations :C01DA70 Organic nitrates in combination with psycholeptics


C01DB Quinolone vasodilators

:C01DB01
Flosequinan Flosequinan is a quinolone vasodilator that was discovered and developed by Boots UK and was sold for about a year under the trade name Manoplax. It had been approved in 1992 in the US and UK to treat people with heart failure Heart failure ...


C01DX Other vasodilators used in cardiac diseases

:C01DX01
Itramin tosilate Itramin tosilate (INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation t ...
:C01DX02 Prenylamine :C01DX03
Oxyfedrine Oxyfedrine is a vasodilator and a β adrenoreceptor agonist. It was found to depress the tonicity of coronary vessels, improve myocardial metabolism (so that heart can sustain hypoxia better) and also exert a positive chronotropic and inotropic ...
:C01DX04
Benziodarone Benziodarone is a vasodilator. * Bufeniode has the same aromatic substitution pattern. See also * Amiodarone * Benzbromarone, the brominated analogue of benziodarone, used as an uricosuric * Dronedarone Dronedarone, sold under the brand nam ...
:C01DX05
Carbocromen Carbocromen (chromonar) is a vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The ...
:C01DX06 Hexobendine :C01DX07
Etafenone Etafenone is a vasodilator which has been used as an antianginal An antianginal is a drug used in the treatment of ''angina pectoris'', a symptom of ischaemic heart disease. Examples Drugs used are nitrates, beta blockers, or calcium channel b ...
:C01DX08
Heptaminol Heptaminol is an amino alcohol which is classified as a cardiac stimulant (positive inotropic action). It also increases coronary blood flow along with mild peripheral vasoconstriction. It is sometimes used in the treatment of low blood pressure, ...
:C01DX09
Imolamine Imolamine (INN, BAN; brand names Angolon, Angoril, Circuline, Irri-Cor, Irrigor, Coremax) is a coronary vasodilator which is used in the treatment of angina pectoris and as a local anesthetic. Use patents:Anne Rolland, (1986 to Laboratoires A ...
:C01DX10 Dilazep :C01DX11
Trapidil Trapidil is a vasodilator and an antiplatelet drug. It also acts as an antagonist of platelet-derived growth factor. An analog Analog or analogue may refer to: Computing and electronics * Analog signal, in which information is encoded in a co ...
:C01DX12 Molsidomine :C01DX13
Efloxate Efloxate is a vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the ...
:C01DX14 Cinepazet :C01DX15
Cloridarol Cloridarol (or clobenfurol) is a vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. ...
:C01DX16
Nicorandil Nicorandil is a vasodilatory drug used to treat angina. Angina is chest pain that results from episodes of transient myocardial ischemia. This can be caused by diseases such as atherosclerosis, coronary artery disease and aortic stenosis. Angin ...
:C01DX18 Linsidomine :C01DX19 Nesiritide :C01DX21
Serelaxin Serelaxin (brand name Reasanz; developmental code name RLX-030) is a medication which is marketed in Russia for the treatment of acute heart failure (AHF), targeting the relaxin receptor. It was also under development in other places in the worl ...
:C01DX22
Vericiguat Vericiguat, sold under the brand name Verquvo, is a medication used to reduce the risk of cardiovascular death and hospitalization in certain patients with heart failure after a recent acute decompensation event. It is taken by mouth. Veric ...
:C01DX51
Itramin tosilate Itramin tosilate (INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation t ...
, combinations :C01DX52 Prenylamine, combinations :C01DX53
Oxyfedrine Oxyfedrine is a vasodilator and a β adrenoreceptor agonist. It was found to depress the tonicity of coronary vessels, improve myocardial metabolism (so that heart can sustain hypoxia better) and also exert a positive chronotropic and inotropic ...
, combinations :C01DX54
Benziodarone Benziodarone is a vasodilator. * Bufeniode has the same aromatic substitution pattern. See also * Amiodarone * Benzbromarone, the brominated analogue of benziodarone, used as an uricosuric * Dronedarone Dronedarone, sold under the brand nam ...
, combinations


C01E Other cardiac preparations


C01EA

Prostaglandin The prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are der ...
s

:C01EA01 Alprostadil


C01EB Other cardiac preparations

:C01EB02
Camphor Camphor () is a waxy, colorless solid with a strong aroma. It is classified as a terpenoid and a cyclic ketone. It is found in the wood of the camphor laurel ('' Cinnamomum camphora''), a large evergreen tree found in East Asia; and in the k ...
:C01EB03 Indometacin :C01EB04 Crataegus
glycoside In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycoside ...
s :C01EB05
Creatinolfosfate Creatinolfosfate (creatinol-''O''-phosphate, creatinol phosphate, COP) is a cardiac preparation, not to be confused with phosphocreatine Phosphocreatine, also known as creatine phosphate (CP) or PCr (Pcr), is a phosphorylated form of creatine ...
:C01EB06
Fosfocreatine Phosphocreatine, also known as creatine phosphate (CP) or PCr (Pcr), is a phosphorylated form of creatine that serves as a rapidly mobilizable reserve of high-energy phosphates in skeletal muscle, myocardium and the brain to recycle adenosine ...
:C01EB07
Fructose 1,6-diphosphate Fructose 1,6-bisphosphate, also known as Harden-Young ester, is fructose sugar phosphorylated on carbons 1 and 6 (i.e., is a fructosephosphate). The β-D-form of this compound is common in cells. Upon entering the cell, most glucose and fructose ...
:C01EB09
Ubidecarenone Coenzyme Q, also known as ubiquinone and marketed as CoQ10, is a coenzyme family that is ubiquitous in animals and most bacteria (hence the name ubiquinone). In humans, the most common form is coenzyme Q10 or ubiquinone-10. It is a 1,4-benz ...
:C01EB10
Adenosine Adenosine (symbol A) is an organic compound that occurs widely in nature in the form of diverse derivatives. The molecule consists of an adenine attached to a ribose via a β-N9-glycosidic bond. Adenosine is one of the four nucleoside buildin ...
:C01EB11
Tiracizine Tiracizine is an antiarrhythmic agent. Carbamates Dibenzazepines Carboxamides Dimethylamino compounds {{cardiovascular-drug-stub ...
:C01EB13
Acadesine Acadesine (INN), also known as 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside, AICA-riboside, and AICAR, is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications ...
:C01EB15
Trimetazidine Trimetazidine ( IUPAC: 1-(2,3,4-trimethoxybenzyl)piperazine) is a drug for angina pectoris (chest pain associated with blood flow to the heart) sold under many brand names. Trimetazidine is described as the first cytoprotective anti-ischemic a ...
:C01EB16
Ibuprofen Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis. It may also be used to close a patent ductus ...
:C01EB17 Ivabradine :C01EB18 Ranolazine :C01EB21 Regadenoson :C01EB22 Meldonium :C01EB23 Tiazotic acid


C01EX Other cardiac combination products


See also

*Class II antiarrhythmics (
beta blocking agents Beta blockers, also spelled β-blockers, are a class of medications that are predominantly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack after a first heart attack (secondary prevention). They are al ...
) are in the ATC group C07. *Class IV antiarrhythmics (cardiac calcium channel blockers) are in the ATC group C08D.


References

{{Vasodilators used in cardiac diseases C01