APP-FUBINACA is an
indazole-based
synthetic cannabinoid
Synthetic cannabinoids, or neocannabinoids, are a class of designer drug molecules that Binding affinity, bind to the same receptors to which cannabinoids (Tetrahydrocannabinol, THC, Cannabidiol, CBD and many others) in cannabis plants attach. Th ...
that has been sold online as a
designer drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ...
. Pharmacological testing showed APP-FUBINACA to have only moderate affinity for the
CB1 receptor, with a Ki of 708 nM, while its EC
50 was not tested. It contains a
phenylalanine
Phenylalanine (symbol Phe or F) is an essential α-amino acid with the chemical formula, formula . It can be viewed as a benzyl group substituent, substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of ...
amino acid residue in its structure.
Legality
Sweden's public health agency suggested to classify APP-FUBINACA as hazardous substance on March 24, 2015.
See also
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5F-AB-PINACA
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5F-ADB
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5F-AMB
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5F-APINACA
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AB-FUBINACA
AB-FUBINACA ( AMB-FUBINACA) is a psychoactive drug that acts as a potent agonist for the cannabinoid receptors, with ''K''i values of 0.9 nM at CB1 and 23.2 nM at CB2 and EC50 values of 1.8 nM at CB1 and 3.2 nM at CB2. I ...
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AB-CHFUPYCA
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AB-CHMINACA
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AB-PINACA
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ADB-CHMINACA
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ADB-FUBINACA
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ADB-PINACA
*
ADBICA
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APICA
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APINACA
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APP-BINACA
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BMS-F
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MDMB-CHMICA
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MDMB-FUBINACA
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PX-1
*
PX-2
*
PX-3
References
Cannabinoids
Designer drugs
Indazolecarboxamides
4-Fluorophenyl compounds
{{cannabinoid-stub