5F-AB-PINACA is an
indazole-based
synthetic cannabinoid
Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids ( THC, CBD and many others) in cannabis plants attach. These novel psychoactive substances should not be confused with synth ...
that is derived from a series of compounds originally developed by
Pfizer
Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfize ...
in 2009 as an
analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...
medication, and has been sold online as a
designer drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Des ...
.
5F-AB-PINACA has been reported to be a potent
agonist
An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...
of the
CB1 receptor and
CB2 receptor with
EC50 values of 0.48 nM and 2.6 nM respectively. Its metabolism has been described in literature.
Legality
China
As of October 2015 5F-AB-PINACA is a controlled substance in China.
Germany
5F-AB-PINACA is an
Anlage II controlled substance in Germany as of May 2015.
Singapore
It is also controlled under the Fifth Schedule of the Misuse of Drugs Act (MDA) in Singapore as of May 2015.
See also
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5F-ADB
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5F-AMB
*
5F-CUMYL-PINACA
5F-CUMYL-PINACA (also known as SGT-25 and sometimes sold in e-cigarette form as C-Liquid) is an indazole-3-carboxamide based synthetic cannabinoid. 5F-CUMYL-PINACA acts as a potent agonist for the cannabinoid receptors, with the original patent c ...
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AB-FUBINACA
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AB-CHFUPYCA
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AB-PINACA
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ADB-CHMINACA
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ADB-FUBINACA
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ADB-PINACA
*
ADBICA
*
APICA
*
APINACA
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MDMB-CHMICA
*
PX-3
PX-3 (also known as APP-CHMINACA) is an indazole-based synthetic cannabinoid. It is a potent agonist of the CB1 receptor with a binding affinity of ''K''i = 47.6 nM and was originally developed by Pfizer in 2009 as an analgesic
...
References
{{Cannabinoids
Cannabinoids
Designer drugs
Indazolecarboxamides
Organofluorides
CB1 receptor agonists
CB2 receptor agonists