Science
Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which stu ...
advanced dramatically during the
20th century
The 20th century began on 1 January 1901 (MCMI), and ended on 31 December 2000 (MM). It was the 10th and last century in the 2nd millennium and was marked by new models of scientific understanding, unprecedented scopes of warfare, new modes of ...
. There were new and radical developments in the
physical,
life
Life, also known as biota, refers to matter that has biological processes, such as Cell signaling, signaling and self-sustaining processes. It is defined descriptively by the capacity for homeostasis, Structure#Biological, organisation, met ...
and
human
Humans (''Homo sapiens'') or modern humans are the most common and widespread species of primate, and the last surviving species of the genus ''Homo''. They are Hominidae, great apes characterized by their Prehistory of nakedness and clothing ...
sciences, building on the progress made in the 19th century.
The development of post-Newtonian theories in physics, such as
special relativity
In physics, the special theory of relativity, or special relativity for short, is a scientific theory of the relationship between Spacetime, space and time. In Albert Einstein's 1905 paper, Annus Mirabilis papers#Special relativity,
"On the Ele ...
,
general relativity
General relativity, also known as the general theory of relativity, and as Einstein's theory of gravity, is the differential geometry, geometric theory of gravitation published by Albert Einstein in 1915 and is the current description of grav ...
, and
quantum mechanics
Quantum mechanics is the fundamental physical Scientific theory, theory that describes the behavior of matter and of light; its unusual characteristics typically occur at and below the scale of atoms. Reprinted, Addison-Wesley, 1989, It is ...
led to the development of
nuclear weapons
A nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either nuclear fission, fission (fission or atomic bomb) or a combination of fission and nuclear fusion, fusion reactions (thermonuclear weap ...
. New models of the structure of the atom led to developments in theories of chemistry and the development of new materials such as
nylon
Nylon is a family of synthetic polymers characterised by amide linkages, typically connecting aliphatic or Polyamide#Classification, semi-aromatic groups.
Nylons are generally brownish in color and can possess a soft texture, with some varieti ...
and
plastic
Plastics are a wide range of synthetic polymers, synthetic or Semisynthesis, semisynthetic materials composed primarily of Polymer, polymers. Their defining characteristic, Plasticity (physics), plasticity, allows them to be Injection moulding ...
s. Advances in biology led to large increases in food production, as well as the elimination of diseases such as
polio
Poliomyelitis ( ), commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 75% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe ...
.
A massive amount of new technologies were developed in the 20th century. Technologies such as
electricity
Electricity is the set of physical phenomena associated with the presence and motion of matter possessing an electric charge. Electricity is related to magnetism, both being part of the phenomenon of electromagnetism, as described by Maxwel ...
, the
incandescent light bulb
An incandescent light bulb, also known as an incandescent lamp or incandescent light globe, is an electric light that produces illumination by Joule heating a #Filament, filament until it incandescence, glows. The filament is enclosed in a ...
, the
automobile
A car, or an automobile, is a motor vehicle with wheels. Most definitions of cars state that they run primarily on roads, Car seat, seat one to eight people, have four wheels, and mainly transport private transport#Personal transport, peopl ...
and the
phonograph
A phonograph, later called a gramophone, and since the 1940s a record player, or more recently a turntable, is a device for the mechanical and analogue reproduction of sound. The sound vibration Waveform, waveforms are recorded as correspond ...
y, first developed at the end of the 19th century, were perfected and universally deployed. The first
airplane
An airplane (American English), or aeroplane (Commonwealth English), informally plane, is a fixed-wing aircraft that is propelled forward by thrust from a jet engine, Propeller (aircraft), propeller, or rocket engine. Airplanes come in a vari ...
flight occurred in 1903, and by the end of the century large airplanes such as the
Boeing 777
The Boeing 777, commonly referred to as the Triple Seven, is an American long-range wide-body airliner developed and manufactured by Boeing Commercial Airplanes. The 777 is the world's largest twinjet and the most-built wide-body airliner. ...
and
Airbus A330
The Airbus A330 is a wide-body airliner developed and produced by Airbus.
Airbus began developing larger A300 derivatives in the mid–1970s, giving rise to the A330 twinjet as well as the Airbus A340 quadjet, and launched both designs along ...
flew thousands of miles in a matter of hours. The development of the
television
Television (TV) is a telecommunication medium for transmitting moving images and sound. Additionally, the term can refer to a physical television set rather than the medium of transmission. Television is a mass medium for advertising, ...
and
computers
A computer is a machine that can be programmed to automatically carry out sequences of arithmetic or logical operations ('' computation''). Modern digital electronic computers can perform generic sets of operations known as ''programs'', ...
caused massive changes in the dissemination of information.
Astronomy and spaceflight

* A much better understanding of the evolution of the
universe
The universe is all of space and time and their contents. It comprises all of existence, any fundamental interaction, physical process and physical constant, and therefore all forms of matter and energy, and the structures they form, from s ...
was achieved, its
age
Age or AGE may refer to:
Time and its effects
* Age, the amount of time someone has been alive or something has existed
** East Asian age reckoning, an Asian system of marking age starting at 1
* Ageing or aging, the process of becoming older
...
(about 13.8 billion years) was determined, and the
Big Bang
The Big Bang is a physical theory that describes how the universe expanded from an initial state of high density and temperature. Various cosmological models based on the Big Bang concept explain a broad range of phenomena, including th ...
theory on its origin was proposed and generally accepted.
* The age of the
Solar System
The Solar SystemCapitalization of the name varies. The International Astronomical Union, the authoritative body regarding astronomical nomenclature, specifies capitalizing the names of all individual astronomical objects but uses mixed "Sola ...
, including
Earth
Earth is the third planet from the Sun and the only astronomical object known to Planetary habitability, harbor life. This is enabled by Earth being an ocean world, the only one in the Solar System sustaining liquid surface water. Almost all ...
, was determined, and it turned out to be much older than believed earlier: more than 4 billion years, rather than the 20 million years suggested by
Lord Kelvin
William Thomson, 1st Baron Kelvin (26 June 182417 December 1907), was a British mathematician, Mathematical physics, mathematical physicist and engineer. Born in Belfast, he was the Professor of Natural Philosophy (Glasgow), professor of Natur ...
in 1862.
* The planets of the Solar System and their moons were closely observed via numerous
space probe
Uncrewed spacecraft or robotic spacecraft are spacecraft without people on board. Uncrewed spacecraft may have varying levels of autonomy from human input, such as remote control, or remote guidance. They may also be autonomous, in which th ...
s.
Pluto
Pluto (minor-planet designation: 134340 Pluto) is a dwarf planet in the Kuiper belt, a ring of Trans-Neptunian object, bodies beyond the orbit of Neptune. It is the ninth-largest and tenth-most-massive known object to directly orbit the Su ...
was discovered in 1930 on the edge of the Solar System, although in the early 21st century, it was reclassified as a
dwarf planet
A dwarf planet is a small planetary-mass object that is in direct orbit around the Sun, massive enough to be hydrostatic equilibrium, gravitationally rounded, but insufficient to achieve clearing the neighbourhood, orbital dominance like the ...
(planetoid) instead of a planet proper, leaving eight planets.
* No trace of
life
Life, also known as biota, refers to matter that has biological processes, such as Cell signaling, signaling and self-sustaining processes. It is defined descriptively by the capacity for homeostasis, Structure#Biological, organisation, met ...
was discovered on any of the other planets in the Solar System, although it remained undetermined whether some forms of primitive life might exist, or might have existed, somewhere.
Extrasolar planets were observed for the first time.
* In 1969,
Apollo 11
Apollo 11 was a spaceflight conducted from July 16 to 24, 1969, by the United States and launched by NASA. It marked the first time that humans Moon landing, landed on the Moon. Commander Neil Armstrong and Lunar Module pilot Buzz Aldrin l ...
was launched towards the
Moon
The Moon is Earth's only natural satellite. It Orbit of the Moon, orbits around Earth at Lunar distance, an average distance of (; about 30 times Earth diameter, Earth's diameter). The Moon rotation, rotates, with a rotation period (lunar ...
and
Neil Armstrong
Neil Alden Armstrong (August 5, 1930 – August 25, 2012) was an American astronaut and aerospace engineering, aeronautical engineer who, in 1969, became the Apollo 11#Lunar surface operations, first person to walk on the Moon. He was al ...
and
Buzz Aldrin
Buzz Aldrin ( ; born Edwin Eugene Aldrin Jr.; January 20, 1930) is an American former astronaut, engineer and fighter pilot. He made three extravehicular activity, spacewalks as pilot of the 1966 Gemini 12 mission, and was the Lunar Module Eag ...
became the first persons from
Earth
Earth is the third planet from the Sun and the only astronomical object known to Planetary habitability, harbor life. This is enabled by Earth being an ocean world, the only one in the Solar System sustaining liquid surface water. Almost all ...
to walk on another celestial body.
* That same year, Soviet astronomer
Victor Safronov published his book ''Evolution of the protoplanetary cloud and formation of the Earth and the planets''. In this book, almost all major problems of the
planetary formation process were formulated and some of them solved. Safronov's ideas were further developed in the works of
George Wetherill, who discovered ''
runaway accretion''.
* The
Space Race
The Space Race (, ) was a 20th-century competition between the Cold War rivals, the United States and the Soviet Union, to achieve superior spaceflight capability. It had its origins in the ballistic missile-based nuclear arms race between t ...
between the United States and the
Soviet Union
The Union of Soviet Socialist Republics. (USSR), commonly known as the Soviet Union, was a List of former transcontinental countries#Since 1700, transcontinental country that spanned much of Eurasia from 1922 until Dissolution of the Soviet ...
gave a peaceful outlet to the political and military tensions of the
Cold War
The Cold War was a period of global Geopolitics, geopolitical rivalry between the United States (US) and the Soviet Union (USSR) and their respective allies, the capitalist Western Bloc and communist Eastern Bloc, which lasted from 1947 unt ...
, leading to the first
human spaceflight
Human spaceflight (also referred to as manned spaceflight or crewed spaceflight) is spaceflight with a crew or passengers aboard a spacecraft, often with the spacecraft being operated directly by the onboard human crew. Spacecraft can also be ...
with the Soviet Union's
Vostok 1 mission in 1961, and man's first landing on another world—the
Moon
The Moon is Earth's only natural satellite. It Orbit of the Moon, orbits around Earth at Lunar distance, an average distance of (; about 30 times Earth diameter, Earth's diameter). The Moon rotation, rotates, with a rotation period (lunar ...
—with America's
Apollo 11
Apollo 11 was a spaceflight conducted from July 16 to 24, 1969, by the United States and launched by NASA. It marked the first time that humans Moon landing, landed on the Moon. Commander Neil Armstrong and Lunar Module pilot Buzz Aldrin l ...
mission in 1969. Later, the first
space station
A space station (or orbital station) is a spacecraft which remains orbital spaceflight, in orbit and human spaceflight, hosts humans for extended periods of time. It therefore is an artificial satellite featuring space habitat (facility), habitat ...
was launched by the
Soviet space program
The Soviet space program () was the state space program of the Soviet Union, active from 1951 until the dissolution of the Soviet Union in 1991. Contrary to its competitors (NASA in the United States, the European Space Agency in Western Euro ...
. The United States developed the first (and to date only) reusable spacecraft system with the
Space Shuttle program, first launched in 1981. As the century ended, a permanent human presence in space was being founded with the ongoing construction of the
International Space Station
The International Space Station (ISS) is a large space station that was Assembly of the International Space Station, assembled and is maintained in low Earth orbit by a collaboration of five space agencies and their contractors: NASA (United ...
.
* In addition to human spaceflight, uncrewed space probes became a practical and relatively inexpensive form of exploration. The first orbiting space probe, ''
Sputnik 1
Sputnik 1 (, , ''Satellite 1''), sometimes referred to as simply Sputnik, was the first artificial Earth satellite. It was launched into an elliptical low Earth orbit by the Soviet Union on 4 October 1957 as part of the Soviet space program ...
'', was launched by the
Soviet Union
The Union of Soviet Socialist Republics. (USSR), commonly known as the Soviet Union, was a List of former transcontinental countries#Since 1700, transcontinental country that spanned much of Eurasia from 1922 until Dissolution of the Soviet ...
in 1957. Over time, a massive system of artificial satellites was placed into orbit around Earth. These satellites greatly advanced navigation, communications, military intelligence, geology, climate, and numerous other fields. Also, by the end of the 20th century, uncrewed probes had visited the Moon,
Mercury,
Venus
Venus is the second planet from the Sun. It is often called Earth's "twin" or "sister" planet for having almost the same size and mass, and the closest orbit to Earth's. While both are rocky planets, Venus has an atmosphere much thicker ...
,
Mars
Mars is the fourth planet from the Sun. It is also known as the "Red Planet", because of its orange-red appearance. Mars is a desert-like rocky planet with a tenuous carbon dioxide () atmosphere. At the average surface level the atmosph ...
,
Jupiter
Jupiter is the fifth planet from the Sun and the List of Solar System objects by size, largest in the Solar System. It is a gas giant with a Jupiter mass, mass more than 2.5 times that of all the other planets in the Solar System combined a ...
,
Saturn
Saturn is the sixth planet from the Sun and the second largest in the Solar System, after Jupiter. It is a gas giant, with an average radius of about 9 times that of Earth. It has an eighth the average density of Earth, but is over 95 tim ...
,
Uranus
Uranus is the seventh planet from the Sun. It is a gaseous cyan-coloured ice giant. Most of the planet is made of water, ammonia, and methane in a Supercritical fluid, supercritical phase of matter, which astronomy calls "ice" or Volatile ( ...
,
Neptune
Neptune is the eighth and farthest known planet from the Sun. It is the List of Solar System objects by size, fourth-largest planet in the Solar System by diameter, the third-most-massive planet, and the densest giant planet. It is 17 t ...
, and various asteroids and comets. The
Hubble Space Telescope
The Hubble Space Telescope (HST or Hubble) is a space telescope that was launched into low Earth orbit in 1990 and remains in operation. It was not the Orbiting Solar Observatory, first space telescope, but it is one of the largest and most ...
, launched in 1990, greatly expanded the understanding of the Universe and brought brilliant images to TV and computer screens around the world.
Biology and medicine
*
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian ...
was unanimously accepted and significantly developed. The
structure of DNA was determined in 1953 by
James Watson
James Dewey Watson (born April 6, 1928) is an American molecular biology, molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper in ''Nature (journal), Nature'' proposing the Nucleic acid ...
,
Francis Crick
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the Nucleic acid doub ...
,
Rosalind Franklin and
Maurice Wilkins,
following by developing techniques which allow to read DNA sequences and culminating in starting the
Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a ...
(not finished in the 20th century) and
cloning the first mammal in 1996.
* The role of
sexual reproduction
Sexual reproduction is a type of reproduction that involves a complex life cycle in which a gamete ( haploid reproductive cells, such as a sperm or egg cell) with a single set of chromosomes combines with another gamete to produce a zygote tha ...
in evolution was understood, and
bacterial conjugation was discovered.
* The convergence of various sciences for the formulation of the
modern evolutionary synthesis (produced between 1936 and 1947), providing a widely accepted account of
evolution
Evolution is the change in the heritable Phenotypic trait, characteristics of biological populations over successive generations. It occurs when evolutionary processes such as natural selection and genetic drift act on genetic variation, re ...
.
*
Placebo
A placebo ( ) can be roughly defined as a sham medical treatment. Common placebos include inert tablets (like sugar pills), inert injections (like saline), sham surgery, and other procedures.
Placebos are used in randomized clinical trials ...
-
controlled,
randomized,
blinded clinical trial
Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel v ...
s became a powerful tool for testing new medicines.
*
Antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy ...
drastically reduced mortality from
bacterial diseases and their
prevalence
In epidemiology, prevalence is the proportion of a particular population found to be affected by a medical condition (typically a disease or a risk factor such as smoking or seatbelt use) at a specific time. It is derived by comparing the number o ...
.
* A
vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verifi ...
was developed for
polio
Poliomyelitis ( ), commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 75% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe ...
, ending a worldwide epidemic. Effective vaccines were also developed for a number of other serious infectious diseases, including
influenza
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These sympto ...
,
diphtheria, pertussis (whooping cough), tetanus,
measles
Measles (probably from Middle Dutch or Middle High German ''masel(e)'', meaning "blemish, blood blister") is a highly contagious, Vaccine-preventable diseases, vaccine-preventable infectious disease caused by Measles morbillivirus, measles v ...
,
mumps
MUMPS ("Massachusetts General Hospital Utility Multi-Programming System"), or M, is an imperative, high-level programming language with an integrated transaction processing key–value database. It was originally developed at Massachusetts Gen ...
,
rubella (German measles),
chickenpox,
hepatitis A, and
hepatitis B.
*
Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent dise ...
and
vaccination
Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating ...
led to the eradication of the
smallpox
Smallpox was an infectious disease caused by Variola virus (often called Smallpox virus), which belongs to the genus '' Orthopoxvirus''. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (W ...
virus in humans.
*
X-ray
An X-ray (also known in many languages as Röntgen radiation) is a form of high-energy electromagnetic radiation with a wavelength shorter than those of ultraviolet rays and longer than those of gamma rays. Roughly, X-rays have a wavelength ran ...
s became powerful diagnostic tool for wide spectrum of diseases, from bone fractures to cancer. In the 1960s,
computerized tomography was invented. Other important diagnostic tools developed were
sonography
Medical ultrasound includes diagnostic techniques (mainly imaging) using ultrasound, as well as therapeutic applications of ultrasound. In diagnosis, it is used to create an image of internal body structures such as tendons, muscles, joints ...
and
magnetic resonance imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to generate pictures of the anatomy and the physiological processes inside the body. MRI scanners use strong magnetic fields, magnetic field gradients, and ...
.
* Development of
vitamins
Vitamins are organic molecules (or a set of closely related molecules called vitamers) that are essential to an organism in small quantities for proper metabolic function. Essential nutrients cannot be synthesized in the organism in suff ...
virtually eliminated
scurvy
Scurvy is a deficiency disease (state of malnutrition) resulting from a lack of vitamin C (ascorbic acid). Early symptoms of deficiency include weakness, fatigue, and sore arms and legs. Without treatment, anemia, decreased red blood cells, gum d ...
and other vitamin-deficiency diseases from industrialized societies.
* New psychiatric drugs were developed. These include
antipsychotic
Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of Psychiatric medication, psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), p ...
s for treating
hallucination
A hallucination is a perception in the absence of an external stimulus that has the compelling sense of reality. They are distinguishable from several related phenomena, such as dreaming ( REM sleep), which does not involve wakefulness; pse ...
s and
delusion
A delusion is a fixed belief that is not amenable to change in light of conflicting evidence. As a pathology, it is distinct from a belief based on false or incomplete information, confabulation, dogma, illusion, hallucination, or some other m ...
s, and
antidepressant
Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction.
Common side effects of antidepressants include Xerostomia, dry mouth, weight gain, dizziness, headaches, akathi ...
s for treating depression.
* The role of
tobacco smoking
Tobacco smoking is the practice of burning tobacco and ingesting the resulting smoke. The smoke may be inhaled, as is done with cigarettes, or released from the mouth, as is generally done with pipes and cigars. The practice is believed to hav ...
in the causation of cancer and other diseases was proven during the 1950s (see
British Doctors Study).
* New methods for cancer treatment, including
chemotherapy
Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs (list of chemotherapeutic agents, chemotherapeutic agents or alkylating agents) in a standard chemotherapy re ...
,
radiation therapy
Radiation therapy or radiotherapy (RT, RTx, or XRT) is a therapy, treatment using ionizing radiation, generally provided as part of treatment of cancer, cancer therapy to either kill or control the growth of malignancy, malignant cell (biology), ...
, and
immunotherapy, were developed. As a result, cancer could often be
cure
A cure is a substance or procedure that resolves a medical condition. This may include a medication, a surgery, surgical operation, a lifestyle change, or even a philosophical shift that alleviates a person's suffering or achieves a state of heali ...
d or placed in
remission.
* The development of
blood typing and
blood banking made
blood transfusion
Blood transfusion is the process of transferring blood products into a person's Circulatory system, circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used ...
safe and widely available.
* The
invention
An invention is a unique or novelty (patent), novel machine, device, Method_(patent), method, composition, idea, or process. An invention may be an improvement upon a machine, product, or process for increasing efficiency or lowering cost. It m ...
and development of
immunosuppressive drugs and
tissue typing made
organ and tissue transplantation a clinical reality.
* New methods for
heart surgery were developed, including
pacemakers and
artificial heart
An artificial heart is a artificial organ, device that replaces the human heart, heart. Artificial hearts are typically used as a bridge to heart transplantation, but ongoing research aims to develop a device that could permanently replace the ...
s.
*
Cocaine
Cocaine is a tropane alkaloid and central nervous system stimulant, derived primarily from the leaves of two South American coca plants, ''Erythroxylum coca'' and ''Erythroxylum novogranatense, E. novogranatense'', which are cultivated a ...
/
crack and heroin were found to be dangerous addictive drugs, and their wide usage had been outlawed; mind-altering drugs such as
LSD and
MDMA were discovered and later outlawed. In many countries, a
war on drugs caused prices to soar 10–20 times higher, leading to profitable
black market
A black market is a Secrecy, clandestine Market (economics), market or series of transactions that has some aspect of illegality, or is not compliant with an institutional set of rules. If the rule defines the set of goods and services who ...
drug dealing, and in some countries (e.g. the
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
) to prison inmate sentences being 80% related to drug use by the 1990s.
*
Contraceptive drugs were developed, which reduced population growth rates in industrialized countries, as well as decreased the taboo of
premarital sex throughout many western countries.
* The development of medical
insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabol ...
during the 1920s helped raise the life expectancy of
diabetics to three times of what it had been earlier.
* Vaccines, hygiene and clean water improved health and decreased mortality rates, especially among infants and the young.
Notable diseases
* An
influenza
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These sympto ...
pandemic,
Spanish Flu, killed anywhere from 20 to 100 million people between 1918 and 1919.
* A new
viral disease, called the
Human Immunodeficiency Virus
The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause AIDS, acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of th ...
, or HIV, arose in Africa and subsequently killed millions of people throughout the world. HIV leads to a syndrome called
Acquired Immunodeficiency Syndrome, or AIDS. Treatments for HIV remained inaccessible to many people living with AIDS and HIV in
developing countries
A developing country is a sovereign state with a less-developed Secondary sector of the economy, industrial base and a lower Human Development Index (HDI) relative to developed countries. However, this definition is not universally agreed upon. ...
, and a cure has yet to be discovered.
* Because of increased
life spans, the
prevalence
In epidemiology, prevalence is the proportion of a particular population found to be affected by a medical condition (typically a disease or a risk factor such as smoking or seatbelt use) at a specific time. It is derived by comparing the number o ...
of cancer,
Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems wit ...
,
Parkinson's disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become ...
, and other diseases of
old age
Old age is the range of ages for people nearing and surpassing life expectancy. People who are of old age are also referred to as: old people, elderly, elders, senior citizens, seniors or older adults. Old age is not a definite biological sta ...
increased slightly.
*
Sedentary lifestyle
Sedentary lifestyle is a Lifestyle (social sciences), lifestyle type, in which one is physically inactive and does little or no physical movement and/or exercise. A person living a sedentary lifestyle is often sitting or lying down while enga ...
s, due to labour-saving devices and technology, along with the increase in home entertainment and technology such as television, video games, and the internet contributed to an "epidemic" of
obesity
Obesity is a medical condition, considered by multiple organizations to be a disease, in which excess Adipose tissue, body fat has accumulated to such an extent that it can potentially have negative effects on health. People are classifi ...
, at first in the rich countries, but by the end of the 20th century spreading to the developing world.
Chemistry

In 1903,
Mikhail Tsvet invented
chromatography
In chemical analysis, chromatography is a laboratory technique for the Separation process, separation of a mixture into its components. The mixture is dissolved in a fluid solvent (gas or liquid) called the ''mobile phase'', which carries it ...
, an important analytic technique. In 1904,
Hantaro Nagaoka proposed an early nuclear model of the atom, where electrons orbit a dense massive nucleus. In 1905,
Fritz Haber
Fritz Jakob Haber (; 9 December 1868 – 29 January 1934) was a German chemist who received the Nobel Prize in Chemistry in 1918 for his invention of the Haber process, a method used in industry to synthesize ammonia from nitrogen gas and hydrog ...
and
Carl Bosch developed the
Haber process
The Haber process, also called the Haber–Bosch process, is the main industrial procedure for the ammonia production, production of ammonia. It converts atmospheric nitrogen (N2) to ammonia (NH3) by a reaction with hydrogen (H2) using finely di ...
for making
ammonia
Ammonia is an inorganic chemical compound of nitrogen and hydrogen with the chemical formula, formula . A Binary compounds of hydrogen, stable binary hydride and the simplest pnictogen hydride, ammonia is a colourless gas with a distinctive pu ...
, a milestone in industrial chemistry with deep consequences in agriculture. The Haber process, or Haber-Bosch process, combined
nitrogen
Nitrogen is a chemical element; it has Symbol (chemistry), symbol N and atomic number 7. Nitrogen is a Nonmetal (chemistry), nonmetal and the lightest member of pnictogen, group 15 of the periodic table, often called the Pnictogen, pnictogens. ...
and
hydrogen
Hydrogen is a chemical element; it has chemical symbol, symbol H and atomic number 1. It is the lightest and abundance of the chemical elements, most abundant chemical element in the universe, constituting about 75% of all baryon, normal matter ...
to form ammonia in industrial quantities for production of fertilizer and munitions. The food production for half the world's current population depends on this method for producing fertilizer. Haber, along with
Max Born
Max Born (; 11 December 1882 – 5 January 1970) was a German-British theoretical physicist who was instrumental in the development of quantum mechanics. He also made contributions to solid-state physics and optics, and supervised the work of a ...
, proposed the
Born–Haber cycle as a method for evaluating the lattice energy of an ionic solid. Haber has also been described as the "father of
chemical warfare" for his work developing and deploying chlorine and other poisonous gases during World War I.

In 1905,
Albert Einstein
Albert Einstein (14 March 187918 April 1955) was a German-born theoretical physicist who is best known for developing the theory of relativity. Einstein also made important contributions to quantum mechanics. His mass–energy equivalence f ...
explained
Brownian motion
Brownian motion is the random motion of particles suspended in a medium (a liquid or a gas). The traditional mathematical formulation of Brownian motion is that of the Wiener process, which is often called Brownian motion, even in mathematical ...
in a way that definitively proved atomic theory.
Leo Baekeland
Leo Hendrik Baekeland ( , ; November 14, 1863 – February 23, 1944) was a Belgian chemist. Educated in Belgium and Germany, he spent most of his career in the United States. He is best known for the inventions of Velox photographic paper ...
invented
bakelite
Bakelite ( ), formally , is a thermosetting polymer, thermosetting phenol formaldehyde resin, formed from a condensation reaction of phenol with formaldehyde. The first plastic made from synthetic components, it was developed by Belgian chemist ...
, one of the first commercially successful plastics. In 1909, American physicist
Robert Andrews Millikan – who had studied in Europe under
Walther Nernst and
Max Planck
Max Karl Ernst Ludwig Planck (; ; 23 April 1858 – 4 October 1947) was a German Theoretical physics, theoretical physicist whose discovery of energy quantum, quanta won him the Nobel Prize in Physics in 1918.
Planck made many substantial con ...
– measured the charge of individual electrons with unprecedented accuracy through the
oil drop experiment, in which he measured the electric charges on tiny falling water (and later oil) droplets. His study established that any particular droplet's electrical charge is a multiple of a definite, fundamental value – the electron's charge – and thus a confirmation that all electrons have the same charge and mass. Beginning in 1912, he spent several years investigating and finally proving Albert Einstein's proposed linear relationship between energy and frequency, and providing the first direct
photoelectric support for the
Planck constant
The Planck constant, or Planck's constant, denoted by h, is a fundamental physical constant of foundational importance in quantum mechanics: a photon's energy is equal to its frequency multiplied by the Planck constant, and the wavelength of a ...
. In 1923 Millikan was awarded the Nobel Prize for Physics.
In 1909,
S. P. L. Sørensen
Søren Peter Lauritz Sørensen (9 January 1868 – 12 February 1939) was a Denmark, Danish chemist, known for the introduction of the concept of pH, a scale for measuring acidity and Base (chemistry), alkalinity.
Personal life
Sørensen wa ...
invented the
pH concept and develops methods for measuring acidity. In 1911,
Antonius Van den Broek proposed the idea that the elements on the periodic table are more properly organized by positive nuclear charge rather than atomic weight. In 1911, the first
Solvay Conference was held in Brussels, bringing together most of the most prominent scientists of the day. In 1912,
William Henry Bragg and William Lawrence Bragg proposed Bragg's law and established the field of X-ray crystallography, an important tool for elucidating the crystal structure of substances. In 1912, Peter Debye develops the concept of molecular dipole to describe asymmetric charge distribution in some molecules.
In 1913, Niels Bohr, a Danish physicist, introduced the concepts of
quantum mechanics
Quantum mechanics is the fundamental physical Scientific theory, theory that describes the behavior of matter and of light; its unusual characteristics typically occur at and below the scale of atoms. Reprinted, Addison-Wesley, 1989, It is ...
to atomic structure by proposing what is now known as the Bohr model of the atom, where electrons exist only in strictly defined circular orbits around the nucleus similar to rungs on a ladder. The Bohr Model is a planetary model in which the negatively charged electrons orbit a small, positively charged nucleus similar to the planets orbiting the Sun (except that the orbits are not planar) – the gravitational force of the solar system is mathematically akin to the attractive Coulomb (electrical) force between the positively charged nucleus and the negatively charged electrons.
In 1913, Henry Moseley, working from Van den Broek's earlier idea, introduces concept of atomic number to fix inadequacies of Mendeleev's periodic table, which had been based on atomic weight. The peak of Frederick Soddy's career in radiochemistry was in 1913 with his formulation of the concept of isotopes, which stated that certain elements exist in two or more forms which have different atomic weights but which are indistinguishable chemically. He is remembered for proving the existence of isotopes of certain radioactive elements, and is also credited, along with others, with the discovery of the element protactinium in 1917. In 1913, J. J. Thomson expanded on the work of Wien by showing that charged subatomic particles can be separated by their mass-to-charge ratio, a technique known as mass spectrometry.
In 1916, Gilbert N. Lewis published his seminal article "The Atom of the Molecule", which suggested that a chemical bond is a pair of electrons shared by two atoms. Lewis's model equated the classical chemical bond with the sharing of a pair of electrons between the two bonded atoms. Lewis introduced the "electron dot diagrams" in this paper to symbolize the electronic structures of atoms and molecules. Now known as Lewis structures, they are discussed in virtually every introductory chemistry book. Lewis in 1923 developed the electron pair theory of acids and base (chemistry), base: Lewis redefined an acid as any atom or molecule with an incomplete octet that was thus capable of accepting electrons from another atom; bases were, of course, electron donors. His theory is known as the concept of Lewis acids and bases. In 1923, G. N. Lewis and Merle Randall published ''Thermodynamics and the Free Energy of Chemical Substances'', first modern treatise on chemical thermodynamics.
The 1920s saw a rapid adoption and application of Lewis's model of the electron-pair bond in the fields of organic and coordination chemistry. In organic chemistry, this was primarily due to the efforts of the British chemists Arthur Lapworth, Robert Robinson (organic chemist), Robert Robinson, Martin Lowry, Thomas Lowry, and Christopher Ingold; while in coordination chemistry, Lewis's bonding model was promoted through the efforts of the American chemist Maurice Huggins and the British chemist Nevil Sidgwick.
Quantum chemistry
Some view the birth of quantum chemistry in the discovery of the Schrödinger equation and its application to the hydrogen atom in 1926. However, the 1927 article of Walter Heitler and Fritz London is often recognised as the first milestone in the history of quantum chemistry. This is the first application of
quantum mechanics
Quantum mechanics is the fundamental physical Scientific theory, theory that describes the behavior of matter and of light; its unusual characteristics typically occur at and below the scale of atoms. Reprinted, Addison-Wesley, 1989, It is ...
to the diatomic
hydrogen
Hydrogen is a chemical element; it has chemical symbol, symbol H and atomic number 1. It is the lightest and abundance of the chemical elements, most abundant chemical element in the universe, constituting about 75% of all baryon, normal matter ...
molecule, and thus to the phenomenon of the chemical bond. In the following years much progress was accomplished by Edward Teller, Robert S. Mulliken,
Max Born
Max Born (; 11 December 1882 – 5 January 1970) was a German-British theoretical physicist who was instrumental in the development of quantum mechanics. He also made contributions to solid-state physics and optics, and supervised the work of a ...
, J. Robert Oppenheimer, Linus Pauling, Erich Hückel, Douglas Hartree, Vladimir Aleksandrovich Fock, to cite a few.
Still, skepticism remained as to the general power of quantum mechanics applied to complex chemical systems. The situation around 1930 is described by Paul Dirac:
Hence the quantum mechanical methods developed in the 1930s and 1940s are often referred to as theoretical molecular physics, molecular or atomic physics to underline the fact that they were more the application of quantum mechanics to chemistry and spectroscopy than answers to chemically relevant questions. In 1951, a milestone article in quantum chemistry is the seminal paper of Clemens C. J. Roothaan on Roothaan equations. It opened the avenue to the solution of the self-consistent field equations for small molecules like
hydrogen
Hydrogen is a chemical element; it has chemical symbol, symbol H and atomic number 1. It is the lightest and abundance of the chemical elements, most abundant chemical element in the universe, constituting about 75% of all baryon, normal matter ...
or
nitrogen
Nitrogen is a chemical element; it has Symbol (chemistry), symbol N and atomic number 7. Nitrogen is a Nonmetal (chemistry), nonmetal and the lightest member of pnictogen, group 15 of the periodic table, often called the Pnictogen, pnictogens. ...
. Those computations were performed with the help of tables of integrals which were computed on the most advanced computers of the time.
In the 1940s many physicists turned from molecular physics, molecular or atomic physics to nuclear physics (like J. Robert Oppenheimer or Edward Teller). Glenn T. Seaborg was an American nuclear chemist best known for his work on isolating and identifying transuranium elements (those heavier than uranium). He shared the 1951 Nobel Prize for Chemistry with Edwin McMillan, Edwin Mattison McMillan for their independent discoveries of transuranium elements. Seaborgium was named in his honour, making him one of three people, along
Albert Einstein
Albert Einstein (14 March 187918 April 1955) was a German-born theoretical physicist who is best known for developing the theory of relativity. Einstein also made important contributions to quantum mechanics. His mass–energy equivalence f ...
and Yuri Oganessian, for whom a chemical element was named during his lifetime.
Molecular biology and biochemistry
By the mid 20th century, in principle, the integration of physics and chemistry was extensive, with chemical properties explained as the result of the electronic structure of the atom; Linus Pauling's book on ''The Nature of the Chemical Bond'' used the principles of quantum mechanics to deduce bond angles in ever-more complicated molecules. However, though some principles deduced from quantum mechanics were able to predict qualitatively some chemical features for biologically relevant molecules, they were, till the end of the 20th century, more a collection of rules, observations, and recipes than rigorous ab initio quantitative methods.

This heuristic approach triumphed in 1953 when
James Watson
James Dewey Watson (born April 6, 1928) is an American molecular biology, molecular biologist, geneticist, and zoologist. In 1953, he co-authored with Francis Crick the academic paper in ''Nature (journal), Nature'' proposing the Nucleic acid ...
and
Francis Crick
Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist. He, James Watson, Rosalind Franklin, and Maurice Wilkins played crucial roles in deciphering the Nucleic acid doub ...
deduced the double helical structure of DNA by constructing models constrained by and informed by the knowledge of the chemistry of the constituent parts and the X-ray diffraction patterns obtained by
Rosalind Franklin. This discovery lead to an explosion of research into the biochemistry of life.
In the same year, the Miller–Urey experiment, conducted by Stanley Miller and Harold Urey demonstrated that basic constituents of protein, simple amino acids, could themselves be built up from simpler molecules in a simulation of primordial Process (science), processes on Earth. Though many questions remain about the true nature of the origin of life, this was the first attempt by chemists to study hypothetical processes in the laboratory under controlled conditions.
In 1983 Kary Mullis devised a method for the in-vitro amplification of DNA, known as the polymerase chain reaction (PCR), which revolutionized the chemical processes used in the laboratory to manipulate it. PCR could be used to synthesize specific pieces of DNA and made possible the DNA sequencing, sequencing of DNA of organisms, which culminated in the huge human genome project.
An important piece in the double helix puzzle was solved by one of Pauling's students Matthew Meselson and Frank Stahl, the result of their collaboration (Meselson–Stahl experiment) has been called as "the most beautiful experiment in biology".
They used a centrifugation technique that sorted molecules according to differences in weight. Because nitrogen atoms are a component of DNA, they were labelled and therefore tracked in replication in bacteria.
Late 20th century

In 1970, John Pople developed the Gaussian (software), Gaussian program greatly easing computational chemistry calculations. In 1971, Yves Chauvin offered an explanation of the reaction mechanism of olefin metathesis reactions. In 1975, Karl Barry Sharpless and his group discovered a stereoselective redox, oxidation reactions including Sharpless epoxidation, Sharpless asymmetric dihydroxylation, and Sharpless oxyamination.
In 1985, Harold Kroto, Robert Curl and Richard Smalley discovered fullerenes, a class of large carbon molecules superficially resembling the geodesic dome designed by architect R. Buckminster Fuller. In 1991, Sumio Iijima used electron microscopy to discover a type of cylindrical fullerene known as a carbon nanotube, though earlier work had been done in the field as early as 1951. This material is an important component in the field of nanotechnology. In 1994, Robert A. Holton and his group achieved the first Holton Taxol total synthesis, total synthesis of Taxol. In 1995, Eric Cornell and Carl Wieman produced the first Bose–Einstein condensate, a substance that displays quantum mechanical properties on the macroscopic scale.
Earth science
In 1912 Alfred Wegener proposed the theory of Continental drift, Continental Drift. This theory suggests that the shapes of continents and matching coastline geology between some continents indicates they were joined in the past and formed a single landmass known as Pangaea; thereafter they separated and drifted like rafts over the ocean floor, currently reaching their present position. Additionally, the theory of continental drift offered a possible explanation as to the formation of mountains; Plate Tectonics built on the theory of continental drift.
Unfortunately, Wegener provided no convincing mechanism for this drift, and his ideas were not generally accepted during his lifetime. Arthur Homes accepted Wegener's theory and provided a mechanism: mantle convection, to cause the continents to move. However, it was not until after the Second World War that new evidence started to accumulate that supported continental drift. There followed a period of 20 extremely exciting years where the Theory of Continental Drift developed from being believed by a few to being the cornerstone of modern Geology. Beginning in 1947 research found new evidence about the ocean floor, and in 1960 Bruce C. Heezen published the concept of mid-ocean ridges. Soon after this, Robert S. Dietz and Harry Hammond Hess, Harry H. Hess proposed that the oceanic crust forms as the seafloor spreads apart along mid-ocean ridges in seafloor spreading. This was seen as confirmation of mantle convection and so the major stumbling block to the theory was removed. Geophysical evidence suggested lateral motion of continents and that oceanic crust is younger than continental crust. This geophysical evidence also spurred the hypothesis of paleomagnetism, the record of the orientation of the Earth's magnetic field recorded in magnetic minerals. British geophysicist Keith Runcorn, S. K. Runcorn suggested the concept of paleomagnetism from his finding that the continents had moved relative to the Earth's magnetic poles. John Tuzo Wilson, Tuzo Wilson, who was a promoter of the sea floor spreading hypothesis and continental drift from the very beginning, added the concept of transform faults to the model, completing the classes of Fault (geology), fault types necessary to make the mobility of the plates on the globe function. A symposium on continental drift was held at the Royal Society of London in 1965 must be regarded as the official start of the acceptance of plate tectonics by the scientific community. The abstracts from the symposium are issued as Blacket, Bullard, Runcorn;1965.In this symposium, Edward Bullard and co-workers showed with a computer calculation how the continents along both sides of the Atlantic would best fit to close the ocean, which became known as the famous "Bullard's Fit". By the late 1960s the weight of the evidence available saw Continental Drift as the generally accepted theory.
Other theories of the causes of climate change fared no better. The principal advances were in observational paleoclimatology, as scientists in various fields of geology worked out methods to reveal ancient climates. Wilmot H. Bradley found that annual varves of clay laid down in lake beds showed climate cycles. A. E. Douglass, Andrew Ellicott Douglass saw strong indications of climate change in tree rings. Noting that the rings were thinner in dry years, he reported climate effects from solar variations, particularly in connection with the 17th-century dearth of sunspots (the Maunder Minimum) noticed previously by William Herschel and others. Other scientists, however, found good reason to doubt that tree rings could reveal anything beyond random regional variations. The value of tree rings for climate study was not solidly established until the 1960s.
Through the 1930s the most persistent advocate of a solar-climate connection was astrophysicist Charles Greeley Abbot. By the early 1920s, he had concluded that the solar constant, solar "constant" was misnamed: his observations showed large variations, which he connected with sunspots passing across the face of the Sun. He and a few others pursued the topic into the 1960s, convinced that sunspot variations were a main cause of climate change. Other scientists were skeptical.
Nevertheless, attempts to connect the solar cycle with climate cycles were popular in the 1920s and 1930s. Respected scientists announced correlations that they insisted were reliable enough to make predictions. Sooner or later, every prediction failed, and the subject fell into disrepute.
Meanwhile Milutin Milankovitch, building on James Croll's theory, improved the tedious calculations of the varying distances and angles of the Sun's radiation as the Sun and Moon gradually perturbed the Earth's orbit. Some observations of varves (layers seen in the mud covering the bottom of lakes) matched the prediction of a Milankovitch cycle lasting about 21,000 years. However, most geologists dismissed the astronomical theory. For they could not fit Milankovitch's timing to the accepted sequence, which had only four ice ages, all of them much longer than 22,000 years.
In 1938 Guy Stewart Callendar attempted to revive Arrhenius's greenhouse-effect theory. Callendar presented evidence that both temperature and the level in the atmosphere had been rising over the past half-century, and he argued that newer spectroscopic measurements showed that the gas was effective in absorbing infrared in the atmosphere. Nevertheless, most scientific opinion continued to dispute or ignore the theory.

Another clue to the nature of climate change came in the mid-1960s from analysis of deep-sea cores by Cesare Emiliani and analysis of ancient corals by Wallace Broecker and collaborators. Rather than four long ice ages, they found a large number of shorter ones in a regular sequence. It appeared that the timing of ice ages was set by the small orbital shifts of the Milankovitch cycles. While the matter remained controversial, some began to suggest that the climate system is sensitive to small changes and can readily be flipped from a stable state into a different one.
Scientists meanwhile began using computers to develop more sophisticated versions of Arrhenius's calculations. In 1967, taking advantage of the ability of digital computers to integrate absorption curves numerically, Syukuro Manabe and Richard Wetherald made the first detailed calculation of the greenhouse effect incorporating convection (the "Manabe-Wetherald one-dimensional radiative-convective model"). They found that, in the absence of unknown feedbacks such as changes in clouds, a doubling of carbon dioxide from the current level would result in approximately 2 °C increase in global temperature.
By the 1960s, aerosol pollution ("smog") had become a serious local problem in many cities, and some scientists began to consider whether the cooling effect of Atmospheric particulate matter, particulate pollution could affect global temperatures. Scientists were unsure whether the cooling effect of particulate pollution or warming effect of greenhouse gas emissions would predominate, but regardless, began to suspect that human emissions could be disruptive to climate in the 21st century if not sooner. In his 1968 book ''The Population Bomb'', Paul R. Ehrlich wrote, "the greenhouse effect is being enhanced now by the greatly increased level of carbon dioxide... [this] is being countered by low-level clouds generated by contrails, dust, and other contaminants ... At the moment we cannot predict what the overall climatic results will be of our using the atmosphere as a garbage dump."
A 1968 study by the Stanford Research Institute for the American Petroleum Institute noted:
In 1969, NATO was the first candidate to deal with climate change on an international level. It was planned then to establish a hub of research and initiatives of the organization in the civil area, dealing with environmental topics
as acid rain and the greenhouse effect. The suggestion of US President Richard Nixon was not very successful with the administration of German Chancellor Kurt Georg Kiesinger. But the topics and the preparation work done on the NATO proposal by the German authorities gained international momentum, (see e.g. the Stockholm United Nations Conference on the Human Environment 1970) as the government of Willy Brandt started to apply them on the civil sphere instead.
[Die Frühgeschichte der globalen Umweltkrise und die Formierung der deutschen Umweltpolitik(1950–1973) (Early history of the environmental crisis and the setup of German environmental policy 1950–1973), Kai F. Hünemörder, Franz Steiner Verlag, 2004 ]
Also in 1969, Mikhail Budyko published a theory on the ice-albedo feedback, a foundational element of what is today known as Arctic amplification. The same year a similar model was published by William D. Sellers. Both studies attracted significant attention, since they hinted at the possibility for a runaway positive feedback within the global climate system.
In the early 1970s, evidence that aerosols were increasing worldwide encouraged Reid Bryson and some others to warn of the possibility of severe cooling. Meanwhile, the new evidence that the timing of ice ages was set by predictable orbital cycles suggested that the climate would gradually cool, over thousands of years. For the century ahead, however, a survey of the scientific literature from 1965 to 1979 found 7 articles predicting cooling and 44 predicting warming (many other articles on climate made no prediction); the warming articles were cited much more often in subsequent scientific literature.
Several scientific panels from this time period concluded that more research was needed to determine whether warming or cooling was likely, indicating that the trend in the scientific literature had not yet become a consensus.
John Sawyer (meteorologist), John Sawyer published the study ''Man-made Carbon Dioxide and the "Greenhouse" Effect'' in 1972. He summarized the knowledge of the science at the time, the anthropogenic attribution of the carbon dioxide greenhouse gas, distribution and exponential rise, findings which still hold today. Additionally he accurately predicted the rate of global warming for the period between 1972 and 2000.
The mainstream news media at the time exaggerated the warnings of the minority who expected imminent cooling. For example, in 1975, ''Newsweek'' magazine published a story that warned of "ominous signs that the Earth's weather patterns have begun to change."
The article continued by stating that evidence of global cooling was so strong that meteorologists were having "a hard time keeping up with it."
On 23 October 2006, ''Newsweek'' issued an update stating that it had been "spectacularly wrong about the near-term future".
In the first two "Reports for the Club of Rome" in 1972 and 1974, the anthropogenic climate changes by increase as well as by waste heat were mentioned. About the latter John Holdren wrote in a study cited in the 1st report, "... that global thermal pollution is hardly our most immediate environmental threat. It could prove to be the most inexorable, however, if we are fortunate enough to evade all the rest." Simple global-scale estimates that recently have been actualized and confirmed by more refined model calculations
show noticeable contributions from waste heat to global warming after the year 2100, if its growth rates are not strongly reduced (below the averaged 2% p.a. which occurred since 1973).
Evidence for warming accumulated. By 1975, Manabe and Wetherald had developed a three-dimensional Global climate model that gave a roughly accurate representation of the current climate. Doubling in the model's atmosphere gave a roughly 2 °C rise in global temperature. Several other kinds of computer models gave similar results: it was impossible to make a model that gave something resembling the actual climate and not have the temperature rise when the concentration was increased.
The 1979 World Climate Conference (12 to 23 February) of the World Meteorological Organization concluded "it appears plausible that an increased amount of carbon dioxide in the atmosphere can contribute to a gradual warming of the lower atmosphere, especially at higher latitudes....It is possible that some effects on a regional and global scale may be detectable before the end of this century and become significant before the middle of the next century."
In July 1979 the United States National Research Council published a report,
concluding (in part):

By the early 1980s, the slight cooling trend from 1945 to 1975 had stopped. Aerosol pollution had decreased in many areas due to environmental legislation and changes in fuel use, and it became clear that the cooling effect from aerosols was not going to increase substantially while carbon dioxide levels were progressively increasing.
Hansen and others published the 1981 study ''Climate impact of increasing atmospheric carbon dioxide'', and noted:
In 1982, Greenland ice cores drilled by Hans Oeschger, Willi Dansgaard, and collaborators revealed dramatic temperature oscillations in the space of a century in the distant past. The most prominent of the changes in their record corresponded to the violent Younger Dryas climate oscillation seen in shifts in types of pollen in lake beds all over Europe. Evidently drastic climate changes were possible within a human lifetime.
In 1985 a joint UNEP/WMO/ICSU Conference on the "Assessment of the Role of Carbon Dioxide and Other Greenhouse Gases in Climate Variations and Associated Impacts" concluded that greenhouse gases "are expected" to cause significant warming in the next century and that some warming is inevitable.
Meanwhile, ice cores drilled by a Franco-Soviet team at the Vostok Station in Antarctica showed that and temperature had gone up and down together in wide swings through past ice ages. This confirmed the -temperature relationship in a manner entirely independent of computer climate models, strongly reinforcing the emerging scientific consensus. The findings also pointed to powerful biological and geochemical feedbacks.
In June 1988, James E. Hansen made one of the first assessments that human-caused warming had already measurably affected global climate. Shortly after, a "Toronto Conference on the Changing Atmosphere, World Conference on the Changing Atmosphere: Implications for Global Security" gathered hundreds of scientists and others in Toronto. They concluded that the changes in the atmosphere due to human pollution "represent a major threat to international security and are already having harmful consequences over many parts of the globe," and declared that by 2005 the world would be well-advised to push its emissions some 20% below the 1988 level.
The 1980s saw important breakthroughs with regard to global environmental challenges. Ozone depletion was mitigated by the Vienna Convention for the Protection of the Ozone Layer, Vienna Convention (1985) and the Montreal Protocol (1987). Acid rain was mainly regulated on national and regional levels.
Colors indicate temperature anomalies (NASA/NOAA; 20 January 2016).
In 1988 the WMO established the Intergovernmental Panel on Climate Change with the support of the UNEP. The IPCC continues its work through the present day, and issues a series of Assessment Reports and supplemental reports that describe the state of scientific understanding at the time each report is prepared. Scientific developments during this period are summarized about once every five to six years in the IPCC Assessment Reports which were published in 1990 (IPCC First Assessment Report, First Assessment Report), 1995 (IPCC Second Assessment Report, Second Assessment Report), 2001 (IPCC Third Assessment Report, Third Assessment Report), 2007 (IPCC Fourth Assessment Report, Fourth Assessment Report), and 2013/2014 (IPCC Fifth Assessment Report, Fifth Assessment Report).
Since the 1990s, research on climate change has expanded and grown, linking many fields such as atmospheric sciences, numerical modeling, behavioral sciences, geology and economics, or Climate security, security.
Engineering and technology

One of the prominent traits of the 20th century was the dramatic growth of technology. Organized research and practice of science led to advancement in the fields of communication, engineering, travel, medicine, and war.
* The number and types of home appliances increased dramatically due to advancements in technology, electricity availability, and increases in wealth and leisure time. Such basic appliances as washing machines, clothes dryers, furnaces, exercise machines, refrigerators, freezers, electric stoves, and vacuum cleaners all became popular from the 1920s through the 1950s. The microwave oven was built on 25 October 1955 and became popular during the 1980s and have become a standard in all homes by the 1990s. Radios were popularized as a form of entertainment during the 1920s, which extended to television during the 1950s. Cable and satellite television spread rapidly during the 1980s and 1990s. Personal computers began to enter the home during the 1970s–1980s as well. The age of the portable music player grew during the 1960s with the development of the transistor radio, Stereo 8, 8-track and Compact Cassette, cassette tapes, which slowly began to replace gramophone record, record players These were in turn replaced by the CD during the late 1980s and 1990s. The proliferation of the Internet in the mid-to-late 1990s made digital distribution of music (mp3s) possible. Videocassette recorder, VCRs were popularized in the 1970s, but by the end of the 20th century, DVD players were beginning to replace them, making the VHS obsolete by the end of the first decade of the 21st century.
* The first airplane was flown in 1903. With the engineering of the faster jet engine in the 1940s, mass air travel became commercially viable.
* The assembly line made mass production of the automobile viable. By the end of the 20th century, billions of people had automobiles for personal transportation. The combination of the automobile, motor boats and air travel allowed for unprecedented personal mobility. In western nations, motor vehicle accidents became the greatest cause of death for young people. However, expansion of divided highways reduced the death rate.
* The triode, triode tube, transistor and integrated circuit successively revolutionized electronics and computers, leading to the proliferation of the personal computer in the 1980s and cell phones and the public-use Internet in the 1990s.
* New materials, most notably stainless steel, Velcro, silicone, polytetrafluoroethylene, teflon, and
plastic
Plastics are a wide range of synthetic polymers, synthetic or Semisynthesis, semisynthetic materials composed primarily of Polymer, polymers. Their defining characteristic, Plasticity (physics), plasticity, allows them to be Injection moulding ...
s such as polystyrene, polyvinyl chloride, PVC, polyethylene, and
nylon
Nylon is a family of synthetic polymers characterised by amide linkages, typically connecting aliphatic or Polyamide#Classification, semi-aromatic groups.
Nylons are generally brownish in color and can possess a soft texture, with some varieti ...
came into widespread use for many various applications. These materials typically have tremendous performance gains in strength, temperature, chemical resistance, or mechanical properties over those known prior to the 20th century.
* Aluminium became an inexpensive metal and became second only to iron in use.
* Semiconductor materials were discovered, and methods of production and purification developed for use in electronic devices. Silicon became one of the purest substances ever produced.
* Thousands of chemicals were developed for industrial processing and home use.
Mathematics
The 20th century saw mathematics become a major profession. As in most areas of study, the explosion of knowledge in the scientific age has led to specialization: by the end of the century there were hundreds of specialized areas in mathematics and the Mathematics Subject Classification was dozens of pages long.
Mathematics Subject Classification 2000
/ref> Every year, thousands of new Ph.D.s in mathematics were awarded, and jobs were available in both teaching and industry. More and more mathematical journals were published and, by the end of the century, the development of the World Wide Web led to online publishing. Mathematical collaborations of unprecedented size and scope took place. An example is the classification of finite simple groups (also called the "enormous theorem"), whose proof between 1955 and 1983 required 500-odd journal articles by about 100 authors, and filling tens of thousands of pages.
In a 1900 speech to the International Congress of Mathematicians, David Hilbert set out a list of Hilbert's problems, 23 unsolved problems in mathematics. These problems, spanning many areas of mathematics, formed a central focus for much of 20th-century mathematics. Today, 10 have been solved, 7 are partially solved, and 2 are still open. The remaining 4 are too loosely formulated to be stated as solved or not.
In 1929 and 1930, it was proved the truth or falsity of all statements formulated about the natural numbers plus one of addition and multiplication, was Decidability (logic), decidable, i.e. could be determined by some algorithm. In 1931, Kurt Gödel found that this was not the case for the natural numbers plus both addition and multiplication; this system, known as Peano arithmetic, was in fact incompleteness theorem, incompletable. (Peano arithmetic is adequate for a good deal of number theory, including the notion of prime number.) A consequence of Gödel's two incompleteness theorems is that in any mathematical system that includes Peano arithmetic (including all of mathematical analysis, analysis and geometry), truth necessarily outruns proof, i.e. there are true statements that Incompleteness theorem, cannot be proved within the system. Hence mathematics cannot be reduced to mathematical logic, and David Hilbert's dream of making all of mathematics complete and consistent needed to be reformulated.
In 1963, Paul Cohen (mathematician), Paul Cohen proved that the continuum hypothesis is logical independence, independent of (could neither be proved nor disproved from) the ZFC, standard axioms of set theory. In 1976, Wolfgang Haken and Kenneth Appel used a computer to prove the four color theorem. Andrew Wiles, building on the work of others, proved Fermat's Last Theorem in 1995. In 1998 Thomas Callister Hales proved the Kepler conjecture.
Differential geometry came into its own when Albert Einstein
Albert Einstein (14 March 187918 April 1955) was a German-born theoretical physicist who is best known for developing the theory of relativity. Einstein also made important contributions to quantum mechanics. His mass–energy equivalence f ...
used it in general relativity
General relativity, also known as the general theory of relativity, and as Einstein's theory of gravity, is the differential geometry, geometric theory of gravitation published by Albert Einstein in 1915 and is the current description of grav ...
. Entirely new areas of mathematics such as mathematical logic, topology, and John von Neumann's game theory changed the kinds of questions that could be answered by mathematical methods. All kinds of Mathematical structure, structures were abstracted using axioms and given names like metric spaces, topological spaces etc. As mathematicians do, the concept of an abstract structure was itself abstracted and led to category theory. Grothendieck and Jean-Pierre Serre, Serre recast algebraic geometry using Sheaf (mathematics), sheaf theory. Large advances were made in the qualitative study of dynamical systems theory, dynamical systems that Henri Poincaré, Poincaré had begun in the 1890s.
Measure theory was developed in the late 19th and early 20th centuries. Applications of measures include the Lebesgue integral, Kolmogorov's axiomatisation of probability theory, and ergodic theory. Knot theory greatly expanded. Quantum mechanics led to the development of functional analysis. Other new areas include Laurent Schwartz's Distribution (mathematics), distribution theory, Fixed-point theorem, fixed point theory, singularity theory and René Thom's catastrophe theory, model theory, and Benoit Mandelbrot, Mandelbrot's fractals. Lie theory with its Lie groups and Lie algebras became one of the major areas of study.
Non-standard analysis, introduced by Abraham Robinson, rehabilitated the infinitesimal approach to calculus, which had fallen into disrepute in favour of the theory of Limit of a function, limits, by extending the field of real numbers to the Hyperreal numbers which include infinitesimal and infinite quantities. An even larger number system, the surreal numbers were discovered by John Horton Conway in connection with combinatorial games.
The development and continual improvement of computers, at first mechanical analog machines and then digital electronic machines, allowed Private industry, industry to deal with larger and larger amounts of data to facilitate mass production and distribution and communication, and new areas of mathematics were developed to deal with this: Alan Turing's computability theory; Computational complexity theory, complexity theory; Derrick Henry Lehmer's use of ENIAC to further number theory and the Lucas-Lehmer test; Rózsa Péter's recursive function theory; Claude Shannon's information theory; signal processing; data analysis; Mathematical optimization, optimization and other areas of operations research. In the preceding centuries much mathematical focus was on calculus and continuous functions, but the rise of computing and communication networks led to an increasing importance of discrete mathematics, discrete concepts and the expansion of combinatorics including graph theory. The speed and data processing abilities of computers also enabled the handling of mathematical problems that were too time-consuming to deal with by pencil and paper calculations, leading to areas such as numerical analysis and symbolic computation. Some of the most important methods and algorithms of the 20th century are: the simplex algorithm, the fast Fourier transform, error-correcting codes, the Kalman filter from control theory and the RSA algorithm of public-key cryptography.
Physics
* New areas of physics, like special relativity
In physics, the special theory of relativity, or special relativity for short, is a scientific theory of the relationship between Spacetime, space and time. In Albert Einstein's 1905 paper, Annus Mirabilis papers#Special relativity,
"On the Ele ...
, general relativity
General relativity, also known as the general theory of relativity, and as Einstein's theory of gravity, is the differential geometry, geometric theory of gravitation published by Albert Einstein in 1915 and is the current description of grav ...
, and quantum mechanics
Quantum mechanics is the fundamental physical Scientific theory, theory that describes the behavior of matter and of light; its unusual characteristics typically occur at and below the scale of atoms. Reprinted, Addison-Wesley, 1989, It is ...
, were developed during the first half of the century. In the process, the internal structure of atoms came to be clearly understood, followed by the discovery of elementary particles.
* It was found that all the known forces can be traced to only four fundamental interactions. It was discovered further that two forces, electromagnetism and weak interaction, can be merged in the electroweak interaction, leaving only three different fundamental interactions.
* Discovery of nuclear reactions, in particular nuclear fusion, finally revealed the source of sun, solar energy.
*Radiocarbon dating was invented, and became a powerful technique for determining the age of Prehistory, prehistoric animals and plants as well as History, historical objects.
* Stellar nucleosynthesis was refined as a theory in 1954 by Fred Hoyle; the theory was supported by astronomical evidence that showed chemical elements were created by nuclear fusion reactions within stars.
Quantum mechanics
Social sciences
* Ivan Pavlov developed the theory of classical conditioning.
* The Austrian School of economic theory gained in prominence.
References
{{20th century
20th century in science,