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The year 1500 AD in
science Science is a systematic discipline that builds and organises knowledge in the form of testable hypotheses and predictions about the universe. Modern science is typically divided into twoor threemajor branches: the natural sciences, which stu ...
and
technology Technology is the application of Conceptual model, conceptual knowledge to achieve practical goals, especially in a reproducible way. The word ''technology'' can also mean the products resulting from such efforts, including both tangible too ...
included many events, some of which are listed here.


Astronomy

* June 1–24 –
Johannes Werner Johann(es) Werner (; February 14, 1468 – May 1522) was a German mathematician. He was born in Nuremberg, Germany, where he became a parish priest. His primary work was in astronomy, mathematics, and geography, although he was also considered a ...
tracks the movement of a
comet A comet is an icy, small Solar System body that warms and begins to release gases when passing close to the Sun, a process called outgassing. This produces an extended, gravitationally unbound atmosphere or Coma (cometary), coma surrounding ...
. It has been suggested that this was
C/1861 J1 The Great Comet of 1861, formally designated C/1861 J1 and 1861 II, is a long-period comet that was visible to the naked eye for approximately 3 months. It was categorized as a great comet—one of the eight greatest comets of the 19th century ...
. * November 5–6 –
Nicolaus Copernicus Nicolaus Copernicus (19 February 1473 – 24 May 1543) was a Renaissance polymath who formulated a mathematical model, model of Celestial spheres#Renaissance, the universe that placed heliocentrism, the Sun rather than Earth at its cen ...
observes a
lunar eclipse A lunar eclipse is an astronomical event that occurs when the Moon moves into the Earth's shadow, causing the Moon to be darkened. Such an alignment occurs during an eclipse season, approximately every six months, during the full moon phase, ...
from Rome.


Cartography

*
Map of Juan de la Cosa The map of Juan de la Cosa is a world map that includes the earliest known representation of the New World and the first depiction of the equator and the Tropic of Cancer on a nautical chart. The map is attributed to the Castilian navigator and ...
, the earliest to show the
Americas The Americas, sometimes collectively called America, are a landmass comprising the totality of North America and South America.''Webster's New World College Dictionary'', 2010 by Wiley Publishing, Inc., Cleveland, Ohio. When viewed as a sing ...
. * ''approx. date'' –
Johannes Stabius Johannes Stabius (Johann Stab) (1450–1522) was an Austrian cartographer and astronomer of Vienna who developed, around 1500, the heart-shape (cordiform) projection map later developed further by Johannes Werner. It is called the '' Werner map ...
introduces the "
Werner projection The Werner projection is a pseudoconic equal-area map projection sometimes called the Stab-Werner or Stabius-Werner projection. Like other heart-shaped projections, it is also categorized as cordiform. ''Stab-Werner'' refers to two originators: ...
".


Cryptography

* ''approx. date'' –
Johannes Trithemius Johannes Trithemius (; 1 February 1462 – 13 December 1516), born Johann Heidenberg, was a German Benedictine abbot and a polymath who was active in the German Renaissance as a Lexicography, lexicographer, chronicler, Cryptography, cryptograph ...
of Spanheim writes ''Steganographia'' ("hidden writing"). Copies of the manuscript circulate for a hundred years.


Earth science

*
Leonardo da Vinci Leonardo di ser Piero da Vinci (15 April 1452 - 2 May 1519) was an Italian polymath of the High Renaissance who was active as a painter, draughtsman, engineer, scientist, theorist, sculptor, and architect. While his fame initially rested o ...
, finding many
fossils A fossil (from Classical Latin , ) is any preserved remains, impression, or trace of any once-living thing from a past geological age. Examples include bones, shells, exoskeletons, stone imprints of animals or microbes, objects preserved ...
in canal building sites, proposes that fossil shells of marine animals are found on mountains because Earth undergoes transformations that cause areas once submerged to become exposed.


Exploration

* March 9–April 22 – Expedition of
Pedro Álvares Cabral Pedro Álvares Cabral (; born Pedro Álvares de Gouveia; ) was a Portuguese nobleman, military commander, navigator and explorer regarded as the European discoverer of Brazil. He was the first human in history to ever be on four continents, ...
, with thirteen
caravel The caravel (Portuguese language, Portuguese: , ) is a small sailing ship developed by the Portuguese that may be rigged with just lateen sails, or with a combination of lateen and Square rig, square sails. It was known for its agility and s ...
s, sails from
Lisbon Lisbon ( ; ) is the capital and largest city of Portugal, with an estimated population of 567,131, as of 2023, within its administrative limits and 3,028,000 within the Lisbon Metropolitan Area, metropolis, as of 2025. Lisbon is mainlan ...
to Brazil, which he claims for Portugal. * August 10 ( St. Lawrence's day) – Diogo Dias becomes the first European to sight the island of
Madagascar Madagascar, officially the Republic of Madagascar, is an island country that includes the island of Madagascar and numerous smaller peripheral islands. Lying off the southeastern coast of Africa, it is the world's List of islands by area, f ...
(which he names ''São Lourenço''). *
Alonso de Ojeda Alonso de Ojeda (; c. 1466 – c. 1515) was a Spanish explorer, governor and conquistador. He is famous for having named Venezuela, which he explored during his first two expeditions, for having been the first European to visit Guyana, Curaçao ...
and
Amerigo Vespucci Amerigo Vespucci ( , ; 9 March 1454 – 22 February 1512) was an Italians, Italian explorer and navigator from the Republic of Florence for whom "Naming of the Americas, America" is named. Vespucci participated in at least two voyages of the A ...
return to Spain from their expedition to
Venezuela Venezuela, officially the Bolivarian Republic of Venezuela, is a country on the northern coast of South America, consisting of a continental landmass and many Federal Dependencies of Venezuela, islands and islets in the Caribbean Sea. It com ...
.


Medicine

* ''approx. date'' – Jakob Nufer, a
Swiss Swiss most commonly refers to: * the adjectival form of Switzerland * Swiss people Swiss may also refer to: Places * Swiss, Missouri * Swiss, North Carolina * Swiss, West Virginia * Swiss, Wisconsin Other uses * Swiss Café, an old café located ...
pig gelder, supposedly performs the first recorded successful
caesarean section Caesarean section, also known as C-section, cesarean, or caesarean delivery, is the Surgery, surgical procedure by which one or more babies are Childbirth, delivered through an incision in the mother's abdomen. It is often performed because va ...
on a living woman.


Pharmaceutics

* Hieronymus Brunschwygk's ''Liber de arte distillandi de simplicibus'', known as the "Small Book (of Distillation)", describes
medicinal herb Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical compounds for various functions, including Plant defense against h ...
s and the construction of
still A still is an apparatus used to distillation, distill liquid mixtures by heating to selectively Boiling, boil and then cooling to Condensation, condense the vapor. A still uses the same concepts as a basic Distillation#Laboratory_procedures, ...
s for processing them. He will publish his "Big Book", dealing with the same subjects, in 1512.


Technology

*
Leonardo da Vinci Leonardo di ser Piero da Vinci (15 April 1452 - 2 May 1519) was an Italian polymath of the High Renaissance who was active as a painter, draughtsman, engineer, scientist, theorist, sculptor, and architect. While his fame initially rested o ...
draws a
wheel-lock A wheellock, wheel-lock, or wheel lock is a friction-wheel mechanism which creates a spark that causes a firearm to fire. It was the next major development in firearms technology after the matchlock, and the first self-igniting firearm. Its name ...
musket A musket is a muzzle-loaded long gun that appeared as a smoothbore weapon in the early 16th century, at first as a heavier variant of the arquebus, capable of penetrating plate armour. By the mid-16th century, this type of musket gradually dis ...
, the first known appearance of this type of ignition, in which a spring mechanism causes a ratchet to strike sparks from iron and pyrites or flint. It will come into use, replacing
match A match is a tool for starting a fire. Typically, matches are made of small wooden sticks or stiff paper. One end is coated with a material that can be ignited by friction generated by striking the match against a suitable surface. Wooden matc ...
ignition, about 15 years later. By this date, he has also designed the first
helicopter A helicopter is a type of rotorcraft in which Lift (force), lift and thrust are supplied by horizontally spinning Helicopter rotor, rotors. This allows the helicopter to VTOL, take off and land vertically, to hover (helicopter), hover, and ...
(although it is probably unworkable). * Defence of
Pisa Pisa ( ; ) is a city and ''comune'' (municipality) in Tuscany, Central Italy, straddling the Arno just before it empties into the Ligurian Sea. It is the capital city of the Province of Pisa. Although Pisa is known worldwide for the Leaning Tow ...
demonstrates the effectiveness of the ''
trace italienne A bastion fort or ''trace italienne'' (a phrase derived from non-standard French, meaning 'Italian outline') is a fortification in a style developed during the early modern period in response to the ascendancy of gunpowder weapons such as c ...
'' form of
fortification A fortification (also called a fort, fortress, fastness, or stronghold) is a military construction designed for the defense of territories in warfare, and is used to establish rule in a region during peacetime. The term is derived from Lati ...
. *
Ottaviano Petrucci Ottaviano Petrucci ( Fossombrone, 18 June 1466 – Venice, 7 May 1539) was an Italian printer. His '' Harmonice Musices Odhecaton'', a collection of chansons printed in 1501, is commonly misidentified as the first book of sheet music printed from ...
(Ottavio de'Petrucci) prints music with
movable type Movable type (US English; moveable type in British English) is the system and technology of printing and typography that uses movable Sort (typesetting), components to reproduce the elements of a document (usually individual alphanumeric charac ...
in
Venice Venice ( ; ; , formerly ) is a city in northeastern Italy and the capital of the Veneto Regions of Italy, region. It is built on a group of 118 islands that are separated by expanses of open water and by canals; portions of the city are li ...
.


Births

*
Hernando de Alarcón Hernando de Alarcón (born 1500) was a Spanish explorer and navigator of the 16th century, noted for having led a 1540 expedition to the Colorado River Delta, during which he became one of the first Europeans to ascend the Colorado River fro ...
, Spanish
navigator A navigator is the person on board a ship or aircraft responsible for its navigation.Grierson, MikeAviation History—Demise of the Flight Navigator FrancoFlyers.org website, October 14, 2008. Retrieved August 31, 2014. The navigator's prim ...
(died
1541 __NOTOC__ Year 1541 ( MDXLI) was a common year starting on Saturday of the Julian calendar. Events January–March * January 4 – Leonardo Cattaneo della Volta is elected to a two-year term as the new Doge of the Republic o ...
) *
Ruy López de Villalobos Ruy López de Villalobos (;  – 23 April 1546) was a Spanish explorer who led a failed attempt to colonize the Philippines in 1544, attempting to assert Spanish control there under the terms of the treaties of Tordesillas and Zaragoza. U ...
, Spanish
explorer Exploration is the process of exploring, an activity which has some Expectation (epistemic), expectation of Discovery (observation), discovery. Organised exploration is largely a human activity, but exploratory activity is common to most organis ...
(died
1546 Year 1546 ( MDXLVI) was a common year starting on Friday of the Julian calendar. Events January–March * January 11 – (''Tenbun 15, 20th day of the 12th month''): Ashikaga YoshifushiTitsingh p. 381 n.b., Ashikaga Yoshifushi cha ...
) * ''approx. date'' ** Pierre Desceliers, French
cartographer Cartography (; from , 'papyrus, sheet of paper, map'; and , 'write') is the study and practice of making and using maps. Combining science, aesthetics and technique, cartography builds on the premise that reality (or an imagined reality) can ...
(died
1558 __NOTOC__ Year 1558 ( MDLVIII) was a common year starting on Saturday of the Julian calendar. Events January–March * January 7 – French troops, led by Francis, Duke of Guise, take Calais, the last continental possession o ...
) **
Ambrosius Ehinger Ambrosius Ehinger, also (Ambrosio Alfínger in Spanish) Dalfinger, Thalfinger, (ca. 1500 in Thalfingen near Ulm – 31 May 1533 near Chinácota in modern-day Colombia) was a German conquistador and the first governor of the Welser conces ...
,
Bavaria Bavaria, officially the Free State of Bavaria, is a States of Germany, state in the southeast of Germany. With an area of , it is the list of German states by area, largest German state by land area, comprising approximately 1/5 of the total l ...
n explorer of South America (k.
1533 Year 1533 ( MDXXXIII) was a common year starting on Wednesday of the Julian calendar. Events January–March * January 25 – King Henry VIII of England formally but secretly marries Anne Boleyn, who becomes his second queen cons ...
) ** Bartolomeo Maranta, Italian
physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...
and
botanist Botany, also called plant science, is the branch of natural science and biology studying plants, especially Plant anatomy, their anatomy, Plant taxonomy, taxonomy, and Plant ecology, ecology. A botanist or plant scientist is a scientist who s ...
(died
1571 Year 1571 ( MDLXXI) was a common year starting on Monday of the Julian calendar. Events January–March * January 11 – The Austrian nobility are granted freedom of religion. * January 23 – The Royal Exchange opens in Lond ...
) ** Paarangot Jyeshtadevan Namboodiri,
Kerala Kerala ( , ) is a States and union territories of India, state on the Malabar Coast of India. It was formed on 1 November 1956, following the passage of the States Reorganisation Act, by combining Malayalam-speaking regions of the erstwhile ...
n
mathematician A mathematician is someone who uses an extensive knowledge of mathematics in their work, typically to solve mathematical problems. Mathematicians are concerned with numbers, data, quantity, mathematical structure, structure, space, Mathematica ...
and
astronomer An astronomer is a scientist in the field of astronomy who focuses on a specific question or field outside the scope of Earth. Astronomers observe astronomical objects, such as stars, planets, natural satellite, moons, comets and galaxy, galax ...
(died
1610 Some have suggested that 1610 may mark the beginning of the Anthropocene, or the 'Age of Man', marking a fundamental change in the relationship between humans and the Earth system, but earlier starting dates (ca. 1000 C.E.) have received broa ...
) **
Niccolò Fontana Tartaglia Nicolo, known as Tartaglia (; 1499/1500 – 13 December 1557), was an Italian mathematician, engineer (designing fortifications), a surveyor (of topography, seeking the best means of defense or offense) and a bookkeeper from the then Republi ...
, Italian mathematician (died
1557 __NOTOC__ Year 1557 ( MDLVII) was a common year starting on Friday of the Julian calendar. Events January–March * January 4 – Pietro Giovanni Chiavica Cibo becomes the new Doge of the Republic of Genoa for a term of 2 ye ...
)


Deaths

* May 29 –
Bartolomeu Dias Bartolomeu Dias ( – 29 May 1500) was a Portuguese mariner and explorer. In 1488, he became the first European navigator to round the Cape Agulhas, southern tip of Africa and to demonstrate that the most effective southward route for ships lies ...
, Portuguese explorer (b. c. 1451) (drowned at sea)


References

{{reflist 1500 16th century in science 1500s in science