Α-PCYP
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α-PCyP (α-PyrrolidinoCyclohexanoPhenone) is a
stimulant Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase alertness. They are used for various purposes, such as enhancing attention, motivation, cognition, ...
drug of the
cathinone Cathinone (; also known as β-ketoamphetamine) is a monoamine alkaloid found in the shrub ''Catha edulis'' (khat) and is chemically similar to ephedrine, cathine, methcathinone and other amphetamines. It is probably the main contributor to t ...
class that has been sold online as a
designer drug A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ...
. In a series of alpha-substituted pyrrolidinyl cathinone derivatives developed in 2015, the alpha-cyclopentyl derivative was found to have around the same potency ''in vitro'' as an
inhibitor Inhibitor or inhibition may refer to: Biology * Enzyme inhibitor, a substance that binds to an enzyme and decreases the enzyme's activity * Reuptake inhibitor, a substance that increases neurotransmission by blocking the reuptake of a neurotransmi ...
of the
dopamine transporter The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded for in humans by the ''SLC6A3'' gene (also known as ''DAT1''), that pumps the neurotransmitter dopamine out of the synaptic cleft ba ...
as the alpha-propyl derivative α-PVP, while the alpha-cyclohexyl derivative α-PCyP was around twice as strong.


See also

* PCPy * Picilorex * α-PHP *
α-PHiP α-Pyrrolidinoisohexanophenone (mainly known as A-PiHP or α-PiHP) is a stimulant drug of the Substituted cathinone, cathinone class that has been sold online as a designer drug. It acts as a potent Norepinephrine–dopamine reuptake inhibitor, ...
* Alpha-D2PV *
βk-Ephenidine 2-(Ethylamino)-1,2-diphenylethanone (also known as α-ethylamino-deoxybenzoin, ±-(Ethylamino)benzyl(phenyl)-ketone and βk-Ephenidine) is a chemical compound which was first invented in 1955, researched by ICI in 1969 as an antidepressant, and ...
*
Diphenidine Diphenidine (1,2-DEP, DPD, DND) is a dissociative anesthetic that has been sold as a designer drug. Diphenidine was first synthesized in 1924 using a Bruylants reaction similar to the one later employed in the discovery of phencyclidine in 1 ...
*
Indapyrophenidone Indapyrophenidone is a synthetic drug of the cathinone class that has been sold online as a designer drug. The substance is the indanyl-α-phenyl analogue of the stimulant drug α-PVP; however, it is also structurally related to diarylethylami ...
*
UWA-101 UWA-101 (also known as α-cyclopropyl-MDMA) is a phenethylamine derivative researched as a potential treatment for Parkinson's disease. Its chemical structure is very similar to that of the illegal drug MDMA, the only difference being the replac ...
*
Zylofuramine Zylofuramine is a stimulant drug. It was developed in 1961, and was intended for use as an appetite suppressant and for the treatment of senile dementia in the elderly, but there is little information about it and it does not appear to have ever ...


References

Pyrrolidinophenones Designer drugs Serotonin-norepinephrine-dopamine releasing agents {{nervous-system-drug-stub