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Weighted Network
A weighted network is a network where the ties among nodes have weights assigned to them. A network is a system whose elements are somehow connected. The elements of a system are represented as nodes (also known as actors or vertices) and the connections among interacting elements are known as ties, edges, arcs, or links. The nodes might be neurons, individuals, groups, organisations, airports, or even countries, whereas ties can take the form of friendship, communication, collaboration, alliance, flow, or trade, to name a few. In a number of real-world networks, not all ties in a network have the same capacity. In fact, ties are often associated with weights that differentiate them in terms of their strength, intensity, or capacity On the one hand, Mark Granovetter (1973) argued that the strength of social relationships in social networks is a function of their duration, emotional intensity, intimacy, and exchange of services. On the other, for non-social networks, weights often re ...
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Network Theory
Network theory is the study of graphs as a representation of either symmetric relations or asymmetric relations between discrete objects. In computer science and network science, network theory is a part of graph theory: a network can be defined as a graph in which nodes and/or edges have attributes (e.g. names). Network theory has applications in many disciplines including statistical physics, particle physics, computer science, electrical engineering, biology, archaeology, economics, finance, operations research, climatology, ecology, public health, sociology, and neuroscience. Applications of network theory include logistical networks, the World Wide Web, Internet, gene regulatory networks, metabolic networks, social networks, epistemological networks, etc.; see List of network theory topics for more examples. Euler's solution of the Seven Bridges of Königsberg problem is considered to be the first true proof in the theory of networks. Network optimization N ...
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Weighted Network
A weighted network is a network where the ties among nodes have weights assigned to them. A network is a system whose elements are somehow connected. The elements of a system are represented as nodes (also known as actors or vertices) and the connections among interacting elements are known as ties, edges, arcs, or links. The nodes might be neurons, individuals, groups, organisations, airports, or even countries, whereas ties can take the form of friendship, communication, collaboration, alliance, flow, or trade, to name a few. In a number of real-world networks, not all ties in a network have the same capacity. In fact, ties are often associated with weights that differentiate them in terms of their strength, intensity, or capacity On the one hand, Mark Granovetter (1973) argued that the strength of social relationships in social networks is a function of their duration, emotional intensity, intimacy, and exchange of services. On the other, for non-social networks, weights often re ...
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Social Network Analysis Software
Social network analysis software (SNA software) is software which facilitates quantitative or qualitative analysis of social networks, by describing features of a network either through numerical or visual representation. Overview Networks can consist of anything from families, project teams, classrooms, sports teams, legislatures, nation-states, disease vectors, membership on networking websites like Twitter or Facebook, or even the Internet. Networks can consist of direct linkages between nodes or indirect linkages based upon shared attributes, shared attendance at events, or common affiliations. Network features can be at the level of individual nodes, dyads, triads, ties and/or edges, or the entire network. For example, node-level features can include network phenomena such as betweenness and centrality, or individual attributes such as age, sex, or income. SNA software generates these features from raw network data formatted in an edgelist, adjacency list, or adjacency m ...
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Clustering Coefficient
In graph theory, a clustering coefficient is a measure of the degree to which nodes in a graph tend to cluster together. Evidence suggests that in most real-world networks, and in particular social networks, nodes tend to create tightly knit groups characterised by a relatively high density of ties; this likelihood tends to be greater than the average probability of a tie randomly established between two nodes (Holland and Leinhardt, 1971; Watts and Strogatz, 1998). Two versions of this measure exist: the global and the local. The global version was designed to give an overall indication of the clustering in the network, whereas the local gives an indication of the embeddedness of single nodes. Local clustering coefficient The local clustering coefficient of a vertex (node) in a graph quantifies how close its neighbours are to being a clique (complete graph). Duncan J. Watts and Steven Strogatz introduced the measure in 1998 to determine whether a graph is a small-world netw ...
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Betweenness
Betweenness is an algorithmic problem in order theory about ordering a collection of items subject to constraints that some items must be placed between others.. It has applications in bioinformatics. and was shown to be NP-complete by . Problem statement The input to a betweenness problem is a collection of ordered triples of items. The items listed in these triples should be placed into a total order, with the property that for each of the given triples, the middle item in the triple appears in the output somewhere between the other two items. The items of each triple are not required to be consecutive in the output. Examples As an example, the collection of input triples :(2,1,3), (3,4,5), (1,4,5), (2,4,1), (5,2,3) is satisfied by the output ordering :3, 1, 4, 2, 5 but not by :3, 1, 2, 4, 5. In the first of these output orderings, for all five of the input triples, the middle item of the triple appears between the other two items However, for the second output ordering, item ...
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Dijkstra's Distance Algorithm
Dijkstra's algorithm ( ) is an algorithm for finding the shortest paths between nodes in a graph, which may represent, for example, road networks. It was conceived by computer scientist Edsger W. Dijkstra in 1956 and published three years later. The algorithm exists in many variants. Dijkstra's original algorithm found the shortest path between two given nodes, but a more common variant fixes a single node as the "source" node and finds shortest paths from the source to all other nodes in the graph, producing a shortest-path tree. For a given source node in the graph, the algorithm finds the shortest path between that node and every other. It can also be used for finding the shortest paths from a single node to a single destination node by stopping the algorithm once the shortest path to the destination node has been determined. For example, if the nodes of the graph represent cities and edge path costs represent driving distances between pairs of cities connected by a dir ...
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Closeness Centrality
In a connected graph, closeness centrality (or closeness) of a node is a measure of centrality in a network, calculated as the reciprocal of the sum of the length of the shortest paths between the node and all other nodes in the graph. Thus, the more central a node is, the ''closer'' it is to all other nodes. Closeness was defined by Bavelas (1950) as the reciprocal of the farness, that is: : C_B(x)= \frac. where d(y,x) is the distance (length of the shortest path) between vertices x and y. This unnormalised version of closeness is sometimes known as status When speaking of closeness centrality, people usually refer to its normalized form which represents the average length of the shortest paths instead of their sum. It is generally given by the previous formula multiplied by N-1, where N is the number of nodes in the graph resulting in: : C(x)= \frac. The normalization of closeness simplifies the comparison of nodes in graphs of different sizes. For large graphs, the minus one ...
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Weighted Correlation Network Analysis
Weighted correlation network analysis, also known as weighted gene co-expression network analysis (WGCNA), is a widely used data mining method especially for studying biological networks based on pairwise correlations between variables. While it can be applied to most high-dimensional data sets, it has been most widely used in genomic applications. It allows one to define modules (clusters), intramodular hubs, and network nodes with regard to module membership, to study the relationships between co-expression modules, and to compare the network topology of different networks (differential network analysis). WGCNA can be used as a data reduction technique (related to oblique factor analysis), as a clustering method (fuzzy clustering), as a feature selection method (e.g. as gene screening method), as a framework for integrating complementary (genomic) data (based on weighted correlations between quantitative variables), and as a data exploratory technique. Although WGCNA i ...
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Microarray
A microarray is a multiplex lab-on-a-chip. Its purpose is to simultaneously detect the expression of thousands of genes from a sample (e.g. from a tissue). It is a two-dimensional array on a solid substrate—usually a glass slide or silicon thin-film cell—that assays (tests) large amounts of biological material using high-throughput screening miniaturized, multiplexed and parallel processing and detection methods. The concept and methodology of microarrays was first introduced and illustrated in antibody microarrays (also referred to as antibody matrix) by Tse Wen Chang in 1983 in a scientific publication and a series of patents. The " gene chip" industry started to grow significantly after the 1995 '' Science Magazine'' article by the Ron Davis and Pat Brown labs at Stanford University. With the establishment of companies, such as Affymetrix, Agilent, Applied Microarrays, Arrayjet, Illumina, and others, the technology of DNA microarrays has become the most sophistic ...
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Systems Biology
Systems biology is the computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach ( holism instead of the more traditional reductionism) to biological research. Particularly from the year 2000 onwards, the concept has been used widely in biology in a variety of contexts. The Human Genome Project is an example of applied systems thinking in biology which has led to new, collaborative ways of working on problems in the biological field of genetics. One of the aims of systems biology is to model and discover emergent properties, properties of cells, tissues and organisms functioning as a system whose theoretical description is only possible using techniques of systems biology. These typically involve metabolic networks or cell signaling networks. Overview Systems biology can be considered from a number of ...
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Jose J
Jose is the English transliteration of the Hebrew and Aramaic name ''Yose'', which is etymologically linked to ''Yosef'' or Joseph. The name was popular during the Mishnaic and Talmudic periods. * Jose ben Abin * Jose ben Akabya *Jose the Galilean *Jose ben Halafta *Jose ben Jochanan *Jose ben Joezer of Zeredah * Jose ben Saul Given name Male * Jose (actor), Indian actor * Jose C. Abriol (1918–2003), Filipino priest * Jose Advincula (born 1952), Filipino Catholic Archbishop * Jose Agerre (1889–1962), Spanish writer * Jose Vasquez Aguilar (1900–1980), Filipino educator * Jose Rene Almendras (born 1960), Filipino businessman * Jose T. Almonte (born 1931), Filipino military personnel * Jose Roberto Antonio (born 1977), Filipino developer * Jose Aquino II (born 1956), Filipino politician * Jose Argumedo (born 1988), Mexican professional boxer * Jose Aristimuño, American political strategist * Jose Miguel Arroyo (born 1945), Philippine lawyer * Jose D. Aspiras (1924–199 ...
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Network (mathematics)
In discrete mathematics, and more specifically in graph theory, a graph is a structure amounting to a set of objects in which some pairs of the objects are in some sense "related". The objects correspond to mathematical abstractions called '' vertices'' (also called ''nodes'' or ''points'') and each of the related pairs of vertices is called an ''edge'' (also called ''link'' or ''line''). Typically, a graph is depicted in diagrammatic form as a set of dots or circles for the vertices, joined by lines or curves for the edges. Graphs are one of the objects of study in discrete mathematics. The edges may be directed or undirected. For example, if the vertices represent people at a party, and there is an edge between two people if they shake hands, then this graph is undirected because any person ''A'' can shake hands with a person ''B'' only if ''B'' also shakes hands with ''A''. In contrast, if an edge from a person ''A'' to a person ''B'' means that ''A'' owes money to ''B'', t ...
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