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White Ramus Communicans
The white ramus communicans (: rami communicantes) from Latin ramus (branch) and communicans (communicating) is the preganglionic sympathetic outflow nerve tract from the spinal cord. Each of the thoracic, and the first and second lumbar nerves contribute a white ramus communicans to the adjoining sympathetic ganglion, unlike the gray rami which are located at each spinal level. White rami communicantes contain both myelinated and unmyelinated preganglionic sympathetic fibers, ( GVE and GVA). The white ramus appears white because there are more myelinated than unmyelinated fibers unlike the gray rami. Structure The white rami communicantes are the preganglionic sympathetic outflow from the spinal cord. The cell bodies for the preganglionic sympathetic myelinated fibers in the white rami communicantes lie in the ipsilateral (same sided) intermediolateral cell column in the spinal cord which extends from T1-L2. These rami also contain general visceral afferent fibers (sensory ...
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Spinal Nerve
A spinal nerve is a mixed nerve, which carries Motor neuron, motor, Sensory neuron, sensory, and Autonomic nervous system, autonomic signals between the spinal cord and the body. In the human body there are 31 pairs of spinal nerves, one on each side of the vertebral column. These are grouped into the corresponding cervical vertebrae, cervical, thoracic vertebrae, thoracic, lumbar vertebrae, lumbar, sacral vertebrae, sacral and coccygeal vertebrae, coccygeal regions of the spine. There are eight pairs of cervical nerves, twelve pairs of thoracic nerves, five pairs of lumbar nerves, five pairs of sacral nerves, and one pair of coccygeal nerves. The spinal nerves are part of the peripheral nervous system. Structure Each spinal nerve is a mixed nerve, formed from the combination of nerve root axon, fibers from its Dorsal root of spinal nerve, dorsal and Ventral root of spinal nerve, ventral roots. The dorsal root is the afferent nerve fiber, afferent sensory root and carries sen ...
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Myelinated
Myelin Sheath ( ) is a lipid-rich material that in most vertebrates surrounds the axons of neurons to insulate them and increase the rate at which electrical impulses (called action potentials) pass along the axon. The myelinated axon can be likened to an electrical wire (the axon) with insulating material (myelin) around it. However, unlike the plastic covering on an electrical wire, myelin does not form a single long sheath over the entire length of the axon. Myelin ensheaths part of an axon known as an internodal segment, in multiple myelin layers of a tightly regulated internodal length. The ensheathed segments are separated at regular short unmyelinated intervals, called nodes of Ranvier. Each node of Ranvier is around one micrometre long. Nodes of Ranvier enable a much faster rate of conduction known as saltatory conduction where the action potential recharges at each node to jump over to the next node, and so on till it reaches the axon terminal. At the terminal the ...
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Intermediolateral Cell Column
The intermediolateral nucleus (IML) is located in Rexed lamina VII of the lateral grey column, one of three grey matter columns found in the spinal cord. The intermediolateral cell column exists at vertebral levels T1 – L3. It mediates the entire sympathetic innervation of the body, but the nucleus resides in the grey matter of the spinal cord. Rexed Lamina VII contains several well defined nuclei including the posterior thoracic nucleus (Clarke's column), the intermediolateral nucleus, and the sacral autonomic nucleus. It extends from T1 to L3, and contains the autonomic motor neurons that give rise to the preganglionic fibers of the sympathetic nervous system The sympathetic nervous system (SNS or SANS, sympathetic autonomic nervous system, to differentiate it from the somatic nervous system) is one of the three divisions of the autonomic nervous system, the others being the parasympathetic nervous sy ..., (preganglionic sympathetic general visceral efferents). ...
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Sympathetic Trunk
The sympathetic trunk (sympathetic chain, gangliated cord) is a paired bundle of nerve fibers that run from the base of the skull to the coccyx. It is a major component of the sympathetic nervous system. Structure The sympathetic trunk lies just lateral to the vertebral bodies for the entire length of the vertebral column. It interacts with the anterior rami of spinal nerves by way of rami communicantes. The sympathetic trunk permits preganglionic fibers of the sympathetic nervous system to ascend to spinal levels superior to T1 and descend to spinal levels inferior to L2/3.Greenstein B., Greenstein A. (2002): Color atlas of neuroscience – Neuroanatomy and neurophysiology. Thieme, Stuttgart – New York, . The superior end of it is continued upward through the carotid canal into the skull, and forms a plexus on the internal carotid artery; the inferior part travels in front of the coccyx, where it converges with the other trunk at a structure known as the ganglion impar ...
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Posterior Horn Of Spinal Cord
The grey columns are three regions of the somewhat ridge-shaped mass of grey matter in the spinal cord. These regions present as three columns: the anterior grey column, the posterior grey column, and the lateral grey column, all of which are visible in cross-section of the spinal cord. The anterior grey column is made up of alpha motor neurons, gamma motor neurons, and small neurons thought to be interneurons. It affects the skeletal muscles. The posterior grey column receives several types of sensory information regarding touch and sensation from receptors in the skin, bones, and joints, including fine touch, proprioception, and vibration. It contains the cell bodies of second-order sensory neurons and their synapses with the pseudounipolar first-order sensory neurons (whose cell bodies are located within the sensory ganglia (a.k.a. dorsal root ganglia)). The lateral grey column is only present in the thoracic region and upper lumbar segments (T1-L2). It contains ...
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Synapse
In the nervous system, a synapse is a structure that allows a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or a target effector cell. Synapses can be classified as either chemical or electrical, depending on the mechanism of signal transmission between neurons. In the case of electrical synapses, neurons are coupled bidirectionally with each other through gap junctions and have a connected cytoplasmic milieu. These types of synapses are known to produce synchronous network activity in the brain, but can also result in complicated, chaotic network level dynamics. Therefore, signal directionality cannot always be defined across electrical synapses. Chemical synapses, on the other hand, communicate through neurotransmitters released from the presynaptic neuron into the synaptic cleft. Upon release, these neurotransmitters bind to specific receptors on the postsynaptic membrane, inducing an electrical or chemical response in the target neuron ...
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Dorsal Root Ganglia
A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. The axons of dorsal root ganglion neurons are known as afferents. In the peripheral nervous system, afferents refer to the axons that relay sensory information into the central nervous system (i.e. the brain and the spinal cord). Structure The neurons comprising the dorsal root ganglion are of the pseudo-unipolar type, meaning they have a cell body (soma) with two branches that act as a single axon, often referred to as a ''distal process'' and a ''proximal process''. Unlike the majority of neurons found in the central nervous system, an action potential in posterior root ganglion neuron may initiate in the ''distal process'' in the periphery, bypass the cell body, and continue to propagate along the ''proximal proces ...
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General Visceral Afferent
The general visceral afferent (GVA) fibers conduct sensory impulses (usually pain or reflex sensations) from the internal organs, glands, and blood vessels to the central nervous system. They are considered to be part of the visceral nervous system, which is closely related to the autonomic nervous system, but 'visceral nervous system' and 'autonomic nervous system' are not direct synonyms and care should be taken when using these terms. Unlike the efferent fibers of the autonomic nervous system, the afferent fibers are not classified as either sympathetic or parasympathetic. GVA fibers create referred pain by activating general somatic afferent fibers where the two meet in the posterior grey column. The cranial nerves that contain GVA fibers include the glossopharyngeal nerve (CN IX) and the vagus nerve (CN X). Generally, they are insensitive to cutting, crushing or burning; however, excessive tension in smooth muscle and some pathological conditions produce visceral pain (r ...
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Preganglionic Sympathetic
In the autonomic nervous system, nerve fibers from the central nervous system to the ganglion are known as preganglionic nerve fibers. All preganglionic fibers, whether they are in the sympathetic division or in the parasympathetic division, are cholinergic (that is, these fibers use acetylcholine as their neurotransmitter) and they are myelinated. Sympathetic preganglionic fibers tend to be shorter than parasympathetic preganglionic fibers because sympathetic ganglia are often closer to the spinal cord than are the parasympathetic ganglia. Another major difference between the two ANS (autonomic nervous systems) is divergence. Whereas in the parasympathetic division there is a divergence factor of roughly 1:4, in the sympathetic division there can be a divergence of up to 1:20. This is due to the number of synapses formed by the preganglionic fibers with ganglionic neurons. See also * Nerve fiber * Grey column * Terminal cisterna * Rexed lamina * Postganglionic nerve fiber * ...
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Lumbar Nerves
The lumbar nerves are the five pairs of spinal nerves emerging from the lumbar vertebrae. They are divided into posterior and anterior divisions. Structure The lumbar nerves are five spinal nerves which arise from either side of the spinal cord below the thoracic spinal cord and above the sacral spinal cord. They arise from the spinal cord between each pair of lumbar spinal vertebrae and travel through the intervertebral foramina. The nerves then split into an anterior branch, which travels forward, and a posterior branch, which travels backwards and supplies the area of the back. Posterior divisions The middle divisions of the posterior branches run close to the articular processes of the vertebrae and end in the multifidus muscle. The outer branches supply the erector spinae muscles. The nerves give off branches to the skin. These pierce the aponeurosis of the greater trochanter. Anterior divisions The anterior divisions of the lumbar nerves () increase in size from ...
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General Visceral Afferent Fibers
The general visceral afferent (GVA) fibers conduct sensory impulses (usually pain or reflex sensations) from the internal organs, glands, and blood vessels to the central nervous system. They are considered to be part of the visceral nervous system, which is closely related to the autonomic nervous system, but 'visceral nervous system' and 'autonomic nervous system' are not direct synonyms and care should be taken when using these terms. Unlike the efferent fibers of the autonomic nervous system, the afferent fibers are not classified as either sympathetic or parasympathetic. GVA fibers create referred pain by activating general somatic afferent fibers where the two meet in the posterior grey column. The cranial nerves that contain GVA fibers include the glossopharyngeal nerve (CN IX) and the vagus nerve (CN X). Generally, they are insensitive to cutting, crushing or burning; however, excessive tension in smooth muscle and some pathological conditions produce visceral pa ...
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General Visceral Efferent Fibers
General visceral efferent fibers (GVE), visceral efferents or autonomic efferents are the efferent nerve fibers of the autonomic nervous system (also known as the ''visceral efferent nervous system'') that provide motor innervation to smooth muscle, cardiac muscle, and glands (contrast with special visceral efferent (SVE) fibers) through postganglionic varicosities. GVE fibers may be either sympathetic or parasympathetic. Cranial and sacral spinal fibers are parasympathetic GVE fibers, while thoracic and lumbar spinal cord give rise to sympathetic GVE fibers. The cranial nerves containing GVE fibers include the oculomotor nerve (CN III), the facial nerve (CN VII), the glossopharyngeal nerve (CN IX) and the vagus nerve (CN X).Mehta, Samir et al. Step-Up: A High-Yield, Systems-Based Review for the USMLE Step 1. Baltimore, MD: LWW, 2003. Additional images File:Gray840.png, Sympathetic connections of the ciliary and superior cervical ganglia. File:Gray839.png, Autonomic nervou ...
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