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Wastewater Surveillance
Wastewater surveillance is the process of monitoring wastewater for contaminants. Amongst other uses, it can be used for biosurveillance, to detect the presence of pathogens in local populations, and to detect the presence of psychoactive drugs. One example of this is the use of wastewater monitoring to detect the presence of the SARS-CoV-2 virus in populations during the COVID-19 pandemic. In one study, wastewater surveillance showed signs of SARS-CoV-2 RNA before any cases were detected in the local population. Later in the pandemic, wastewater surveillance was demonstrated to be one technique to detect SARS-CoV-2 variants and to monitor their prevalence over time. Comparison between case based epidemiological records and deep-sequenced wastewater samples validated that the composition of the virus population in the wastewater is in strong agreement with the virus variants circulating in the infected population. Following the 2022-23 reopening surge of COVID-19 cases in China ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Detection Of Monkeypox Virus DNA In Wastewater Samples In The Netherlands
''The'' is a grammatical article in English, denoting nouns that are already or about to be mentioned, under discussion, implied or otherwise presumed familiar to listeners, readers, or speakers. It is the definite article in English. ''The'' is the most frequently used word in the English language; studies and analyses of texts have found it to account for seven percent of all printed English-language words. It is derived from gendered articles in Old English which combined in Middle English and now has a single form used with nouns of any gender. The word can be used with both singular and plural nouns, and with a noun that starts with any letter. This is different from many other languages, which have different forms of the definite article for different genders or numbers. Pronunciation In most dialects, "the" is pronounced as (with the voiced dental fricative followed by a schwa) when followed by a consonant sound, and as (homophone of the archaic pronoun ''thee'') ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academies Of Sciences, Engineering, And Medicine
The National Academies of Sciences, Engineering, and Medicine (NASEM), also known as the National Academies, is a Congressional charter, congressionally chartered organization that serves as the collective scientific national academy of the United States. The name is used interchangeably in two senses: (1) as an umbrella term or parent organization for its three sub-divisions that operate as quasi-independent honorific learned society member organizations known as the National Academy of Sciences (NAS), the National Academy of Engineering (NAE), and the National Academy of Medicine (NAM); and (2) as the brand for studies and reports issued by the unified operating arm of the three academies originally known as the National Research Council (NRC). The National Academies also serve as public policy advisors, research institutes, think tanks, and public administration consultants on issues of public importance or on request by the government. The National Research Council, National ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidemiology
Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and Risk factor (epidemiology), determinants of health and disease conditions in a defined population, and application of this knowledge to prevent diseases. It is a cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying Risk factor (epidemiology), risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, amend interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences. Major areas of epidemiological study include disease causation, transmission (medicine), transmission, outbreak investigation, disease surveillance, environmental epidemiology, forensic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wastewater-based Epidemiology
Wastewater-based epidemiology (or wastewater-based surveillance or sewage chemical-information mining) analyzes wastewater to determine the consumption of, or exposure to, chemicals or pathogens in a population. This is achieved by measuring chemical or biomarkers in wastewater generated by the people contributing to a sewage treatment plant catchment. Wastewater-based epidemiology has been used to estimate illicit drug use in communities or populations, but can be used to measure the consumption of alcohol, caffeine, various pharmaceuticals and other compounds. Wastewater-based epidemiology has also been adapted to measure the load of pathogens such as SARS-CoV-2 in a community. It differs from traditional drug testing, urine or stool testing in that results are population-level rather than individual level. Wastewater-based epidemiology is an interdisciplinary endeavour that draws on input from specialists such as wastewater treatment plant operators, analytical chemists, mo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimicrobial Resistance
Antimicrobial resistance (AMR or AR) occurs when microbes evolve mechanisms that protect them from antimicrobials, which are drugs used to treat infections. This resistance affects all classes of microbes, including bacteria (antibiotic resistance), viruses (antiviral resistance), Parasitic disease, parasites (antiparasitic resistance), and fungi (antifungal resistance). Together, these adaptations fall under the AMR umbrella, posing significant challenges to healthcare worldwide. Misuse and improper management of antimicrobials are primary drivers of this resistance, though it can also occur naturally through genetic mutations and the spread of resistant genes. Antibiotic resistance, a significant AMR subset, enables bacteria to survive antibiotic treatment, complicating infection management and treatment options. Resistance arises through spontaneous mutation, horizontal gene transfer, and increased selective pressure from Antibiotic misuse, antibiotic overuse, both in medicin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contaminants Of Emerging Concern
Contaminants of emerging concern (CEC) is a term used by water quality professionals to describe water pollution, pollutants that have been detected in environmental monitoring samples, that may cause ecological or human health impacts, and typically are not regulated under current environmental laws. Sources of these pollutants include agricultural pollution, agriculture, urban runoff and ordinary household products (such as soaps and disinfectants) and pharmaceuticals that are disposed to sewage treatment plants and subsequently discharged to surface waters. CEC include different substances like pharmaceuticals, personal care products, industrial byproducts, and agricultural chemicals. These substances often bypass regular detection and treatment processes, leading to their unintended persistence in the environment. The complexity of CEC arises not only from their different chemical nature but also from the complex ways they interact with ecosystems and human health. As such, they ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emerging Infectious Disease
An emerging infectious disease (EID) refer to infectious diseases that have either newly appeared in a population or have existed but are rapidly increasing in incidence, geographic range, or severity due to factors such as environmental changes, antimicrobial resistance, and human-animal interactions. The minority that are capable of developing Virulence, efficient transmission between humans can become major Public health, public and Global health, global concerns as potential causes of epidemics or pandemics. Their many impacts can be economic and societal, as well as clinical. EIDs have been increasing steadily since at least 1940. For every decade since 1940, there has been a consistent increase in the number of EID events from wildlife-related zoonosis. Human activity is the primary driver of this increase, with loss of biodiversity a leading mechanism. Emerging infections account for at least 12% of all human pathogens. EIDs can be caused by newly identified microbes, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin one to four (typically two) days after exposure to the virus and last for about two to eight days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia from the virus or a subsequent bacterial infection. Other complications include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus: types A, B, C, and D. Aquatic birds are the primary source of influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and influenza C virus (ICV) primarily infect humans, and influenza D virus (IDV) i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poliovirus
Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species '' Enterovirus C'', in the family of '' Picornaviridae''. There are three poliovirus serotypes, numbered 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only a strand of RNA and a nonenveloped icosahedral protein coat encapsulating it—poliovirus is widely regarded as the simplest significant virus. Poliovirus is one of the most well-characterized viruses, and has become a useful model system for understanding the biology of RNA viruses. Replication cycle Poliovirus infects human cells by binding to an immunoglobulin-like receptor, CD155 (also known as the poliovirus receptor or PVR) on the cell surface. Inte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Centers For Disease Control And Prevention
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency under the Department of Health and Human Services (HHS), and is headquartered in Atlanta, Georgia. The CDC's current nominee for director is Susan Monarez. She became acting director on January 23, 2025, but stepped down on March 24, 2025 when nominated for the director position. On May 14, 2025, Robert F. Kennedy Jr. stated that lawyer Matthew Buzzelli is acting CDC director. However, the CDC web site does not state the acting director's name. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It especially focuses its attention on infectious disease, food borne pathogens, environmental health, occupational safety and h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wastewater
Wastewater (or waste water) is water generated after the use of freshwater, raw water, drinking water or saline water in a variety of deliberate applications or processes. Another definition of wastewater is "Used water from any combination of domestic, industrial, commercial or agricultural activities, surface runoff / storm water, and any sewer inflow or sewer infiltration". In everyday usage, wastewater is commonly a synonym for sewage (also called domestic wastewater or municipal wastewater), which is wastewater that is produced by a community of people. As a generic term, wastewater may also describe water containing contaminants accumulated in other settings, such as: * Industrial wastewater: waterborne waste generated from a variety of industrial processes, such as manufacturing operations, mineral extraction, power generation, or water and wastewater treatment. * Cooling water, is released with potential thermal pollution after use to condense steam or reduce machinery ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Pandemic In Mainland China
The COVID-19 pandemic in mainland China is part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). China was where the first COVID outbreak occurred, the first where authorities imposed drastic measures in response (including lockdowns and face mask mandates), and was one of the first countries to bring the outbreak under control, at least temporarily. The 2019–2020 COVID-19 outbreak in mainland China was the first wave of the disease, and was first manifested as a cluster of mysterious pneumonia cases, mostly related to the Huanan Seafood Market, in Wuhan, the capital of Hubei province. It was first reported to the local government on 27 December 2019 and published on 31 December. On 8 January 2020, a new coronavirus (SARS-CoV-2) was identified as the cause of the pneumonia by Chinese scientists. By 29 January, the virus was found to have spread to all provinces of mainland China. By ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
