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Trioxane
Trioxane refers to any of three isomeric organic compounds composed of a six-membered ring with three carbon atoms and three oxygen atoms, having the molecular formula C3H6O3. Isomers The three isomers are: * 1,2,3-trioxane, a hypothetical compound that is the parent structure of the molozonides * 1,2,4-trioxane, a hypothetical compound whose skeleton occurs as a structural component of some antimalarial agents (artemisinin and similar drugs) * 1,3,5-trioxane, a trimer of formaldehyde Formaldehyde ( , ) (systematic name methanal) is an organic compound with the chemical formula and structure , more precisely . The compound is a pungent, colourless gas that polymerises spontaneously into paraformaldehyde. It is stored as ... used as fuel and in plastics manufacturing, and also as a solid fuel tablet when combined with hexamine References Hypothetical chemical compounds {{Hyp-chem-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artemisinin
Artemisinin () and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to ''Plasmodium falciparum''. It was discovered in 1972 by Tu Youyou, who shared the 2015 Nobel Prize in Physiology or Medicine for her discovery. Artemisinin-based combination therapies (ACTs) are now standard treatment worldwide for ''P. falciparum'' malaria as well as malaria due to other species of ''Plasmodium''. Artemisinin can be extracted from the herb '' Artemisia annua'' (sweet wormwood), which is used in traditional Chinese medicine. Alternatively, it can be prepared by a semi-synthetic method from a precursor compound that can be produced using a genetically engineered yeast, which is much more efficient than extraction from the plant. Artemisinin and its derivatives are all sesquiterpene lactones containing an unusual peroxide bridge. This endoperoxide 1,2,4-trioxane ring is responsible for their antimalarial properties. Few other natural compounds wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hexamine Fuel Tablet
A hexamine fuel tablet (or heat tablet, Esbit) is a form of solid fuel in :wikt:tablet, tablet form. The tablets burn smokelessly, have a high energy density, do not liquefy while burning and leave no ashes. Invented in 1936 in Murrhardt, Germany, the main component is hexamethylenetetramine, hexamine, which was discovered by Aleksandr Butlerov in 1859. Some fuel tablets use 1,3,5-Trioxane, 1,3,5-trioxane as another ingredient. ''Esbit'' is a genericized trademark that people often use to refer to similar products made by other companies. In most countries from the former Soviet bloc, fuel tablets are called ''dry fuel''. Uses The tablets are used for cooking by camping, campers, militaries, and relief organizations. They are often used with hexamine stove, disposable metal stoves that are included with field ration packs. Another common use is to provide a heat source for model steam engines, such as those manufactured by Wilesco and Mamod, and other external combustion eng ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hexamethylenetetramine
Hexamethylenetetramine (HMTA), also known as 1,3,5,7-tetraazaadamantane, is a heterocyclic organic compound with diverse applications. It has the chemical formula (CH2)6N4 and is a white crystalline compound that is highly soluble in water and polar organic solvents. It is useful in the synthesis of other organic compounds, including plastics, pharmaceuticals, and rubber additives. The compound is also used medically for certain conditions. It sublimes in vacuum at 280°C. It has a tetrahedral cage-like structure similar to adamantane. The four vertices are occupied by nitrogen atoms, which are linked by methylene groups. Although the molecular shape defines a cage, no void space is available at the interior. Synthesis, structure, reactivity Hexamethylenetetramine was discovered by Aleksandr Butlerov in 1859. In this article, Butlerov discovered formaldehyde, which he called "dioxymethylen" (methylene dioxide) age 247because his empirical formula for it was incorrect (C4H4O4) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Formaldehyde
Formaldehyde ( , ) (systematic name methanal) is an organic compound with the chemical formula and structure , more precisely . The compound is a pungent, colourless gas that polymerises spontaneously into paraformaldehyde. It is stored as aqueous solutions (formalin), which consists mainly of the hydrate CH2(OH)2. It is the simplest of the aldehydes (). As a precursor to many other materials and chemical compounds, in 2006 the global production of formaldehyde was estimated at 12 million tons per year. It is mainly used in the production of industrial resins, e.g., for particle board and coatings. Formaldehyde also occurs naturally. It is derived from the degradation of serine, dimethylglycine, and lipids. Demethylases act by converting N-methyl groups to formaldehyde. Formaldehyde is classified as a group 1 carcinogen and can cause respiratory and skin irritation upon exposure. Forms Formaldehyde is more complicated than many simple carbon compounds in that i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gary H
Gary may refer to: *Gary (given name), a common masculine given name, including a list of people and fictional characters with the name Places ;Iran * Gary, Iran, Sistan and Baluchestan Province ;United States *Gary (Tampa), Florida *Gary, Indiana * Gary, Maryland * Gary, Minnesota * Gary, South Dakota *Gary, West Virginia * Gary – New Duluth, a neighborhood in Duluth, Minnesota * Gary Air Force Base, San Marcos, Texas * Gary City, Texas Ships * USS ''Gary'' (DE-61), a destroyer escort launched in 1943 * USS ''Gary'' (CL-147), scheduled to be a light cruiser, but canceled prior to construction in 1945 * USS ''Gary'' (FFG-51), a frigate, commissioned in 1984 * USS ''Thomas J. Gary'' (DE-326), a destroyer escort commissioned in 1943 People *Gary (given name), a common masculine given name, including a list of people and fictional characters with the name *Gary (surname), including a list of people with the name * Gary (rapper), South Korean rapper and entertainer * Gary (Argen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimalarial
Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. As of 2018, modern treatments, including for severe malaria, continued to depend on therapies deriving historically from quinine and artesunate, both parenteral (injectable) drugs, expanding from there into the many classes of available modern drugs. Incidence and distribution of the disease ("malaria burden") is expected to remain high, globally, for many years to come; moreover, known antimalarial drugs have repeatedly been observed to elicit resistance in the malaria parasite—including for combination therapies featuring artemisinin, a drug of last resort, where resistance has now been observed in Southeast Asia. As such, the needs for new antimalarial agents and new strategies of treatment (e.g., new c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isomer
In chemistry, isomers are molecules or polyatomic ions with identical molecular formula – that is, the same number of atoms of each element (chemistry), element – but distinct arrangements of atoms in space. ''Isomerism'' refers to the existence or possibility of isomers. Isomers do not necessarily share similar chemical property, chemical or physical property, physical properties. Two main forms of isomerism are structural isomerism, structural (or constitutional) isomerism, in which ''chemical bond, bonds'' between the atoms differ; and stereoisomerism (or spatial isomerism), in which the bonds are the same but the ''relative positions'' of the atoms differ. Isomeric relationships form a hierarchy. Two chemicals might be the same constitutional isomer, but upon deeper analysis be stereoisomers of each other. Two molecules that are the same stereoisomer as each other might be in different conformational forms or be different Isotopologue, isotopologues. The depth of analy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypothetical Compound
A hypothetical chemical compound is a chemical compound that has been conceived of, but is not known to have been synthesized, observed, or isolated (identified or shown to exist). Some hypothetical compounds cannot form at all, due to steric effects (e.g. tetra-''tert''-butylmethane, , chlorine heptafluoride, , or bromine heptafluoride, ) or bond stress (e.g. tetrahedrane ). Others might turn out to be highly unstable, decomposing, isomerizing, polymerizing, rearranging, or disproportionating. Some are thought to exist only briefly as reactive intermediates or in vacuum. Some have no known pathway for synthesis (e.g. hypercubane). Some compounds of radioactive elements have never been synthesized due to their radioactive decay and short half-lives (e.g. francium hydroxide FrOH, radon hexafluoride , astatine heptafluoride , polonium(II) fluoride ). Some "parent compounds" have not been or cannot be isolated, even though stable structural analogs with substituents have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1,2,3-trioxane
Onekama ( ) is a village in Manistee County in the U.S. state of Michigan. The population was 399 at the 2020 census. The village is located on the northeast shore of Portage Lake and is surrounded by Onekama Township. The town's name is derived from ''Ona-ga-maa'', an Anishinaabe word which means "singing water". History The predecessor of the village of Onekama was the settlement of Portage at Portage Point, first established in 1845, at the western end of Portage Lake, at the outlet of Portage Creek. In 1871, when landowners around the land-locked lake became exasperated with the practices of the Portage Sawmill, they took the solution into their own hands and dug a channel through the narrow isthmus, opening a waterway that lowered the lake by and brought it to the same level as Lake Michigan. When this action dried out Portage Creek on May 14, 1871, the settlement, which had only the week before been designated as "Onekama" with a post office under that name, moved to t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
