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Synovectomy
Synovectomy is a procedure where the synovial tissue surrounding a joint is removed. This procedure is typically recommended to provide relief from a condition in which the synovial membrane or the joint lining becomes inflamed and irritated and is not controlled by medication alone. If arthritis (inflammation of the joint) is not controlled, it can lead to irreversible joint damage. The synovial membrane or "synovium" encloses each joint and also secretes a lubricating fluid that allows different joint motions such as rolling, folding and stretching. When the synovium becomes inflamed or irritated, it increases fluid production, resulting in warmth, tenderness, and swelling in and around the joint. A ''synovectomy'' is a procedure often suggested for those with rheumatoid arthritis or other forms of inflammatory arthritis when non-operative treatments have failed. This procedure can be performed in several ways, namely surgical synovectomy, chemical synovectomy and radiological. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Surgeries By Type
Many surgical procedure names can be broken into parts to indicate the meaning. For example, in gastrectomy, "ectomy" is a suffix meaning the removal of a part of the body. "Gastro-" means stomach. Thus, ''gastrectomy'' refers to the surgical removal of the stomach (or sections thereof). "Otomy" means cutting into a part of the body; a ''gastrotomy'' would be cutting into, but not necessarily removing, the stomach. And also "pharyngo" means pharynx, "laryngo" means larynx, "esophag" means esophagus. Thus, "pharyngolaryngoesophagectomy" refers to the surgical removal of the three. The field of minimally invasive surgery has spawned another set of words, such as ''arthroscopic'' or ''laparoscopic'' surgery. These take the same form as above; an arthroscope is a device which allows the inside of the joint to be seen. List of common surgery terms Prefixes * ''mono-'' : one, from the Greek μόνος, ''monos'', "only, single" * ''angio-'' : related to a blood vessel, from the Gr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synovial Membrane
The synovial membrane (also known as the synovial stratum, synovium or stratum synoviale) is a specialized connective tissue that lines the inner surface of capsules of synovial joints and tendon sheath. It makes direct contact with the fibrous membrane on the outside surface and with the synovial fluid lubricant on the inside surface. In contact with the synovial fluid at the tissue surface are many rounded macrophage-like synovial cells (type A) and also type B cells, which are also known as fibroblast-like synoviocytes (FLS). Type A cells maintain the synovial fluid by removing wear-and-tear debris. As for the FLS, they produce hyaluronan, as well as other extracellular components in the synovial fluid. Structure The synovial membrane is variable but often has two layers: * The outer layer, or subintima, can be of almost any type of connective tissue – fibrous (dense collagenous type), adipose (fatty; e.g. in intra-articular fat pads) or areolar (loose collagenous ty ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osmic Acid
Osmium tetroxide (also osmium(VIII) oxide) is the chemical compound with the formula OsO4. The compound is noteworthy for its many uses, despite its toxicity and the rarity of osmium. It also has a number of unusual properties, one being that the solid is volatile. The compound is colourless, but most samples appear yellow. This is most likely due to the presence of the impurity OsO2, which is yellow-brown in colour. In biology, its property of binding to lipids has made it a widely-used stain in electron microscopy. Physical properties Osmium(VIII) oxide forms monoclinic crystals. It has a characteristic acrid chlorine-like odor. The element name osmium is derived from ''osme'', Greek for ''odor''. OsO4 is volatile: it sublimes at room temperature. It is soluble in a wide range of organic solvents. It is also moderately soluble in water, with which it reacts reversibly to form osmic acid (see below). ''Pure'' osmium(VIII) oxide is probably colourless and it has been su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rhenium-186
Naturally occurring rhenium (75Re) is 37.4% 185Re, which is stable (although it is predicted to decay), and 62.6% 187Re, which is unstable but has a very long half-life (4.12×1010 years). Among elements with a known stable isotope, only indium and tellurium similarly occur with a stable isotope in lower abundance than the long-lived radioactive isotope. There are 33 other unstable isotopes recognized, the longest-lived of which are 183Re with a half-life of 70 days, 184Re with a half-life of 38 days, 186Re with a half-life of 3.7186 days, 182Re with a half-life of 64.0 hours, and 189Re with a half-life of 24.3 hours. There are also numerous isomers, the longest-lived of which are 186mRe with a half-life of 200,000 years and 184mRe with a half-life of 177.25 days. All others have half-lives less than a day. List of isotopes , - , rowspan=2, 160Re , rowspan=2 style="text-align:right" , 75 , rowspan=2 style="text-align:right" , 85 , rowspan=2, 159.98212(43)# , rowspan=2, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dysprosium-165
Naturally occurring dysprosium (66Dy) is composed of 7 stable isotopes, 156Dy, 158Dy, 160Dy, 161Dy, 162Dy, 163Dy and 164Dy, with 164Dy being the most abundant (28.18% natural abundance). Twenty-nine radioisotopes have been characterized, with the most stable being 154Dy with a half-life of 3.0 million years, 159Dy with a half-life of 144.4 days, and 166Dy with a half-life of 81.6 hours. All of the remaining radioactive isotopes have half-lives that are less than 10 hours, and the majority of these have half-lives that are less than 30 seconds. This element also has 12 meta states, with the most stable being 165mDy (half-life 1.257 minutes), 147mDy (half-life 55.7 seconds) and 145mDy (half-life 13.6 seconds). The primary decay mode before the most abundant stable isotope, 164Dy, is electron capture, and the primary mode after is beta decay. The primary decay products before 164Dy are terbium isotopes, and the primary products after are holmium isotopes. Dysprosium is the heaviest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erbium-169
Naturally occurring erbium (68Er) is composed of 6 stable isotopes, with 166Er being the most abundant (33.503% natural abundance). 39 radioisotopes have been characterized with between 74 and 112 neutrons, or 142 to 180 nucleons, with the most stable being 169Er with a half-life of 9.4 days, 172Er with a half-life of 49.3 hours, 160Er with a half-life of 28.58 hours, 165Er with a half-life of 10.36 hours, and 171Er with a half-life of 7.516 hours. All of the remaining radioactive isotopes have half-lives that are less than 3.5 hours, and the majority of these have half-lives that are less than 4 minutes. This element also has numerous meta states, with the most stable being 167mEr (t1/2 2.269 seconds). The isotopes of erbium range in atomic weight from 141.9723 u (142Er) to 176.9541 u (177Er). The primary decay mode before the most abundant stable isotope, 166Er, is electron capture, and the primary mode after is beta decay. The primary decay products before 166Er are holm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yttrium-90
Yttrium-90 () is an isotope of yttrium. Yttrium-90 has found a wide range of uses in radiation therapy to treat some forms of cancer. Decay undergoes β− decay to zirconium-90 with a half-life of 64.1 hours and a decay energy of 2.28 MeV with an average beta energy of 0.9336 MeV. It also produces 0.01% 1.7 MeV photons during its decay process to the 0+ state of 90Zr, followed by pair production. The interaction between emitted electrons and matter can lead to the emission of Bremsstrahlung radiation. Production Yttrium-90 is produced by the nuclear decay of strontium-90 which has a half-life of nearly 29 years and is a fission product of uranium used in nuclear reactors. As the strontium-90 decays, chemical high-purity separation is used to isolate the yttrium-90 before precipitation. Medical application 90Y plays a significant role in the treatment of hepatocellular carcinoma (HCC), leukemia, and lymphoma, although it has the potential to treat a range of tumo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rifamycin
The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium '' Amycolatopsis rifamycinica'' or artificially. They are a subclass of the larger family of ansamycins. Rifamycins are particularly effective against mycobacteria, and are therefore used to treat tuberculosis, leprosy, and mycobacterium avium complex (MAC) infections. The rifamycin group includes the "classic" rifamycin drugs as well as the rifamycin derivatives rifampicin (or rifampin), rifabutin, rifapentine, rifalazil and rifaximin. Rifamycin, sold under the trade name Aemcolo, is approved in the United States for treatment of travelers' diarrhea in some circumstances. Bacterium ''Streptomyces mediterranei'' was first isolated in 1957 from a soil sample collected near the beach-side town of St Raphael in southern France. The name was originally given by two microbiologists working with the Italian drug company Group Lepetit SpA in Milan, the Italian Grazia Beretta, and P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rifampicin
Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), ''Mycobacterium avium'' complex, leprosy, and Legionnaires’ disease. It is almost always used together with other antibiotics with two notable exceptions: when given as a "preferred treatment that is strongly recommended" for latent TB infection; and when used as post-exposure prophylaxis to prevent ''Haemophilus influenzae'' type b and meningococcal disease in people who have been exposed to those bacteria. Before treating a person for a long period of time, measurements of liver enzymes and blood counts are recommended. Rifampicin may be given either by mouth or intravenously. Common side effects include nausea, vomiting, diarrhea, and loss of appetite. It often turns urine, sweat, and tears a red or orange color. Liver problems or allergic reactions may occur. It is part of the recommended treatment of active tuberculosis duri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Knee Replacement
Knee replacement, also known as knee arthroplasty, is a surgical procedure to replace the weight-bearing surfaces of the knee joint to relieve pain and disability, most commonly offered when joint pain is not diminished by conservative sources and also for other knee diseases such as rheumatoid arthritis and psoriatic arthritis. In patients with severe deformity from advanced rheumatoid arthritis, trauma, or long-standing osteoarthritis, the surgery may be more complicated and carry higher risk. Osteoporosis does not typically cause knee pain, deformity, or inflammation and is not a reason to perform knee replacement. Other major causes of debilitating pain include meniscus tears, cartilage defects, and ligament tears. Debilitating pain from osteoarthritis is much more common in the elderly. Knee replacement surgery can be performed as a partial or a total knee replacement. In general, the surgery consists of replacing the diseased or damaged joint surfaces of the knee with m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. The disease may also affect other parts of the body, including skin, eyes, lungs, heart, nerves and blood. This may result in a low red blood cell count, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often, symptoms come on gradually over weeks to months. While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. The underlying mechanism involves the body's immune system attacking the joints. This results in inflammation and thickening of the joint capsule. It also affects the underlying bone and cartilage. The diagnosis is made m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biopharmaceutical
A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. Different from totally synthesized pharmaceuticals, they include vaccines, whole blood, blood components, allergenics, somatic cells, gene therapies, tissues, recombinant therapeutic protein, and living medicines used in cell therapy. Biologics can be composed of sugars, proteins, nucleic acids, or complex combinations of these substances, or may be living cells or tissues. They (or their precursors or components) are isolated from living sources—human, animal, plant, fungal, or microbial. They can be used in both human and animal medicine. Terminology surrounding biopharmaceuticals varies between groups and entities, with different terms referring to different subsets of therapeutics within the general biopharmaceutical category. Some regulatory agencies use the terms ''biological ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
