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Sapogenin
Sapogenins are aglycones (non-saccharide moieties) of saponins, a large family of natural products. Sapogenins contain steroid or other triterpene frameworks as their key organic feature. For example, steroidal sapogenins such as tiggenin, neogitogenin, and tokorogenin have been isolated from the tubers of '' Chlorophytum arundinaceum''. Some steroidal sapogenins can serve as a practical starting point for the semisynthesis Semisynthesis, or partial chemical synthesis, is a type of chemical synthesis that uses chemical compounds isolated from natural sources (such as microbiology, microbial cell cultures or plant material) as the starting materials to produce novel ... of particular steroid hormones. Diosgenin and hecogenin are other examples of sapogenins. References Phytochemicals Triterpenes Alcohols {{organic-compound-stub ...
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Steroid
A steroid is an organic compound with four fused compound, fused rings (designated A, B, C, and D) arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and as signal transduction, signaling molecules. Examples include the lipid cholesterol, sex hormones estradiol and testosterone, anabolic steroids, and the anti-inflammatory corticosteroid drug dexamethasone. Hundreds of steroids are found in Fungus, fungi, plants, and animals. All steroids are manufactured in cells from a sterols, sterol: Cholesterol, cholesterol (animals), lanosterol (opisthokonts), or cycloartenol (plants). All three of these molecules are produced via Cyclic compound, cyclization of the triterpene squalene. Structure The steroid nucleus (parent structure, core structure) is called gonane (cyclopentanoperhydrophenanthrene). It is typically composed of seventeen carbon atoms, bonded in fou ...
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Yamogenin
Yamogenin is a chemical compound of the class called sapogenins. It is found in the herb fenugreek Fenugreek (; ''Trigonella foenum-graecum'') is an annual plant in the family Fabaceae, with leaves consisting of three small Glossary_of_leaf_morphology#Leaf_and_leaflet_shapes, obovate to oblong leaflets. It is cultivated worldwide as a semiar ... (''Trigonella foenum-graecum'') and other plants. References Triterpenes Secondary alcohols Spiro compounds Cyclopentanes Tetrahydrofurans Tetrahydropyrans {{alcohol-stub ...
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Diosgenin
Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of '' Dioscorea'' wild yam species, such as the Kokoro. It is also present in smaller amounts in a number of other species. The sugar-free (aglycone) product of such hydrolysis, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. Sources It is present in detectable amounts in '' Costus speciosus'', '' Smilax menispermoidea'', '' Helicteres isora'', species of ''Paris'', '' Aletris'', '' Trigonella'', and ''Trillium'', and in extractable amounts from many species of '' Dioscorea'' – '' D. althaeoides'', '' D. colletti'', '' D. composita'', '' D. floribunda'', '' D. futschauensis'', '' D. gracillima'', '' D. hispida'', '' D. hypoglauca'', '' D. mexicana'', '' D. nipponica'', '' D. panthaica'', '' D. parviflora'', '' D. septemloba'', and '' D. zingiberensis''. Industrial u ...
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Tuber
Tubers are a type of enlarged structure that plants use as storage organs for nutrients, derived from stems or roots. Tubers help plants perennate (survive winter or dry months), provide energy and nutrients, and are a means of asexual reproduction. Stem tubers manifest as thickened rhizomes (underground stems) or stolons (horizontal connections between organisms); examples include the potato and Yam (vegetable), yam. The term ''root tuber'' describes modified lateral roots, as in sweet potatoes, cassava, and dahlias. Terminology The term originates from the Latin , meaning 'lump, bump, or swelling'. Some writers limit the definition of ''tuber'' to structures derived from Plant stem, stems, while others also apply the term to structures derived from roots., p. 124 Stem tubers A stem tuber forms from thickened rhizomes or stolons. The top sides of the tuber produce shoots that grow into typical stems and leaves and the undersides produce roots. They tend to form at the s ...
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Phytochemicals
Phytochemicals are naturally-occurring chemicals present in or extract, extracted from plants. Some phytochemicals are nutrients for the plant, while others are metabolites produced to enhance plant survivability and reproduction. The fields of extracting phytochemicals for manufactured products or applying scientific methods to study phytochemical properties are called ''phytochemistry''. An individual who uses phytochemicals in food chemistry manufacturing or research is a ''phytochemist''. Phytochemicals without a nutrient definition have no confirmed biological activities or proven health benefits when consumed in plant foods. Once phytochemicals in a food enter the digestion process, the fate of individual phytochemicals in the body is unknown due to extensive metabolism of the food in the gastrointestinal tract, producing phytochemical metabolites with different biological properties from those of the parent compound that may have been tested in vitro. Further, the bio ...
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Steroid Hormone
A steroid hormone is a steroid that acts as a hormone. Steroid hormones can be grouped into two classes: corticosteroids (typically made in the adrenal cortex, hence ''cortico-'') and sex steroids (typically made in the gonads or placenta). Within those two classes are five types according to the receptors to which they bind: glucocorticoids and mineralocorticoids (both corticosteroids) and androgens, estrogens, and progestogens (sex steroids). Vitamin D derivatives are a sixth closely related hormone system with homologous receptors. They have some of the characteristics of true steroids as receptor ligands. Steroid hormones help control metabolism, inflammation, immune functions, salt and water balance, development of sexual characteristics, and the ability to withstand injury and illness. The term steroid describes both hormones produced by the body and artificially produced medications that duplicate the action for the naturally occurring steroids. Synthesis The natu ...
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Semisynthesis
Semisynthesis, or partial chemical synthesis, is a type of chemical synthesis that uses chemical compounds isolated from natural sources (such as microbiology, microbial cell cultures or plant material) as the starting materials to produce novel compounds with distinct chemical and medicinal properties. The novel compounds generally have a high molecular weight or a complex molecular structure, more so than those produced by total synthesis from simple starting materials. Semisynthesis is a means of preparing many medicines more cheaply than by total synthesis since fewer chemical steps are necessary. Drugs derived from natural sources are commonly produced either by isolation from their natural source or, as described here, through semisynthesis of an isolated agent. From the perspective of chemical synthesis, living organisms act as highly efficient chemical factories, capable of producing structurally complex compounds through biosynthesis. In contrast, engineered chemical s ...
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Chlorophytum Arundinaceum
''Chlorophytum'' (,''Sunset Western Garden Book,'' 1995:606–607), sometimes colloquially referred to as the spider plants, is a genus of almost 200 species of evergreen perennial flowering plants in the century plant subfamily within the asparagus family. The plants are native to the tropical and subtropical regions of Africa, Australia, and Asia. Depending on species, most ''Chlorophytum'' mature at about 10–60 cm (3"-12") in height, growing out from a central rosette of long, slender leaves of around 15–75 cm (5"-29") in length. The plants tend to have thick, fleshy, tuberous roots, about 0.5-2 cm (0.17"-0.75") thick. The flowers are small and usually white, produced on sparse panicles up to 120 cm (47") long. In certain species, such as ''C. comosum'' (the ubiquitous 'spider plant'), the plants are known to reproduce vegetatively by producing plantlets—baby plants connected by an "umbilical" stem, sprouting from the side of the main mother-plant. O ...
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Aglycone
An aglycone (aglycon or genin) is the chemical compound remaining after the glycosyl group on a glycoside is replaced by a hydrogen atom. For example, the aglycone of a cardiac glycoside would be a steroid A steroid is an organic compound with four fused compound, fused rings (designated A, B, C, and D) arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes t ... molecule. Detection A way to identify aglycone is proposed to extract it from Agave spp. by using H-NMR and Heteronuclear multiple bond correlation (HMBC) experiments. The HMBC experiment can be combined with other techniques such as mass spectrometry to further examine the structure and the function of aglycone. Samples of glycones and glycosides from limonoids can be simultaneously quantified through a high performance liquid chromatography (HPLC) method, where a binary solvent system and a diode array detector separate ...
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