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Risks Of Biotechnology
Biotechnology risk is a form of existential risk from biological sources, such as genetically engineered biological agents. The release of such high-consequence pathogens could be *deliberate (in the form of bioterrorism or biological weapons) *accidental, or *a naturally occurring event. A chapter on biotechnology and biosecurity was included in Nick Bostrom's 2008 anthology ''Global Catastrophic Risks'', which covered risks including viral agents. Since then, new technologies like CRISPR and gene drives have been introduced. While the ability to deliberately engineer pathogens has been constrained to high-end labs run by top researchers, the technology to achieve this is rapidly becoming cheaper and more widespread. For example, the diminishing cost of sequencing the human genome (from $10 million to $1,000), the accumulation of large datasets of genetic information, the discovery of gene drives, and the discovery of CRISPR. Biotechnology risk is therefore a credible explanat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Existential Risk
A global catastrophic risk or a doomsday scenario is a hypothetical event that could damage human well-being on a global scale, endangering or even destroying Modernity, modern civilization. Existential risk is a related term limited to events that could cause full-blown human extinction or permanently and drastically curtail humanity's existence or potential. In the 21st century, a number of academic and non-profit organizations have been established to research global catastrophic and existential risks, formulate potential mitigation measures, and either advocate for or implement these measures. Definition and classification Defining global catastrophic risks The term global catastrophic risk "lacks a sharp definition", and generally refers (loosely) to a risk that could inflict "serious damage to human well-being on a global scale". Humanity has suffered large catastrophes before. Some of these have caused serious damage but were only local in scope—e.g. the Black ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virulence
Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most cases, especially in animal systems, virulence refers to the degree of damage caused by a microbe to its host. The pathogenicity of an organism—its ability to cause disease—is determined by its virulence factors. In the specific context of gene for gene systems, often in plants, virulence refers to a pathogen's ability to infect a resistant host. Virulence can also be transferred using a plasmid. The noun ''virulence'' (Latin noun ) derives from the adjective ''virulent'', meaning disease severity. The word ''virulent'' derives from the Latin word ''virulentus'', meaning "a poisoned wound" or "full of poison". The term ''virulence'' does not only apply to viruses. From an ecological standpoint, virulence is the loss of fitness induced by a parasite upon its host. Virulence can be understood in terms of proximate causes—those specific traits of the pathogen that help make the host ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marc Lipsitch
Marc Lipsitch (born 1969) is an American epidemiologist and Professor in the Department of Epidemiology at the Harvard T.H. Chan School of Public Health, where he is the Director of the Center for Communicable Disease Dynamics. He has worked on modeling the transmission of Coronavirus disease 2019 (COVID-19). Education and early career Lipsitch attended Yale University, where he received his Bachelor of Arts degree in philosophy in 1991. He attended Oxford University as a Rhodes Scholar, studying zoology, and received his Doctor of Philosophy degree in 1995. There, he studied under Robert May and Martin Nowak. He then returned to the United States for his postdoctoral fellowship at Emory University from 1995 to 1999. During that time, he worked at the Centers for Disease Control and Prevention before joining the faculty at Harvard T.H. Chan School of Public Health. Research As an epidemiologist, Lipsitch has focused his research on better understanding the evolution of infe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pandemic
A pandemic ( ) is an epidemic of an infectious disease that has a sudden increase in cases and spreads across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. Widespread endemic (epidemiology), endemic diseases with a stable number of infected individuals such as recurrences of seasonal influenza are generally excluded as they occur simultaneously in large regions of the globe rather than being spread worldwide. Throughout human history, there have been a number of pandemics of diseases such as smallpox. The Black Death, caused by the Plague (disease), Plague, caused the deaths of up to half of the population of Europe in the 14th century. The term ''pandemic'' had not been used then, but was used for later epidemics, including the 1918 Influenza A virus subtype H1N1, H1N1 influenza A pandemic—more commonly known as the Spanish flu—which is the Deadliest pandemics in history, deadliest pandemic in history. The mos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
H5N1
Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes the disease avian influenza (often referred to as "bird flu"). It is enzootic (maintained in the population) in many bird populations, and also panzootic (affecting animals of many species over a wide area). A/H5N1 virus can also infect mammals (including humans) that have been exposed to infected birds; in these cases, symptoms are frequently severe or fatal. A/H5N1 virus is shed in the saliva, mucus, and feces of infected birds; other infected animals may shed bird flu viruses in respiratory secretions and other body fluids (such as milk). The virus can spread rapidly through poultry flocks and among wild birds. An estimated half billion farmed birds have been slaughtered in efforts to contain the virus. Symptoms of A/H5N1 influenza vary according to both the strain of virus underlying the infection and on the species of bird or mammal affected. Classification as either Low Pathogeni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ferret
The ferret (''Mustela furo'') is a small, domesticated species belonging to the family Mustelidae. The ferret is most likely a domesticated form of the wild European polecat (''Mustela putorius''), as evidenced by the ferret's ability to interbreed with European polecats and produce hybrid offspring. Physically, ferrets resemble other mustelids because of their long, slender bodies. Including their tail, the average length of a ferret is about ; they weigh between ; and their fur can be black, brown, white, or a mixture of those colours. The species is sexually dimorphic, with males being considerably larger than females. Ferrets may have been domesticated since ancient times, but there is widespread disagreement because of the sparseness of written accounts and the inconsistency of those which survive. Contemporary scholarship agrees that ferrets were bred for sport, hunting rabbits in a practice known as rabbiting. In North America, the ferret has become an increasingly pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza
Influenza, commonly known as the flu, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin one to four (typically two) days after exposure to the virus and last for about two to eight days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia from the virus or a subsequent bacterial infection. Other complications include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus: types A, B, C, and D. Aquatic birds are the primary source of influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and influenza C virus (ICV) primarily infect humans, and influenza D virus (IDV) i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mouse
A mouse (: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus''). Mice are also popular as pets. In some places, certain kinds of Apodemus, field mice are locally common. They are known to invade homes for food and shelter. Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term ''mouse'' if it is smaller, or ''rat'' if it is larger. The common terms ''rat'' and ''mouse'' are not Taxonomy (biology), taxonomically specific. Typical mice are classified in the genus ''Mus (genus), Mus'', but the term ''mouse'' is not confined to members of ''Mus'' and can also apply to species from other genera such as the deer mouse, deer mouse (''Peromyscus''). Fancy mouse, Domestic mice sold as pets often differ substantially in size f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaccine
A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verified. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and recognize further and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylaxis, prophylactic (to prevent or alleviate the effects of a future infection by a natural or "wild" pathogen), or therapeutic vaccines, therapeutic (to fight a disease that has already occurred, such as cancer vaccine, cancer). Some vaccines offer full sterilizing immunity, in which infection is prevented. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Pest Control
Biological control or biocontrol is a method of controlling pests, whether pest animals such as insects and mites, weeds, or pathogens affecting animals or plants by using other organisms. It relies on predation, parasitism, herbivory, or other natural mechanisms, but typically also involves an active human management role. It can be an important component of integrated pest management (IPM) programs. There are three basic strategies for biological control: classical (importation), where a natural enemy of a pest is introduced in the hope of achieving control; inductive (augmentation), in which a large population of natural enemies are administered for quick pest control; and inoculative (conservation), in which measures are taken to maintain natural enemies through regular reestablishment. Natural enemies of insects play an important part in limiting the densities of potential pests. Biological control agents such as these include predators, parasitoids, pathogens, and com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mousepox
Ectromelia virus (ECTV) is a virus of the family ''Poxviridae'' and the genus ''Orthopoxvirus'' that causes mousepox, a disease of mice. It has only been seen in mouse colonies kept for research purposes but believed that wild populations of mice and other rodents in Europe are naturally infected with ECTV. Mousepox causes skin lesions, a purulent rash on the body of mice, and generalized disease, which can be fatal. It is the only poxvirus to cause disease naturally in mice. History Ectromelia was first discovered in 1930 when scientists started to use mice as a model for examinations and experiments, and was first observed in a colony of laboratory mice in England. The original Hampstead strain of ECTV was discovered in 1930 in a laboratory-mouse colony. Since then, other ECTV strains and outbreaks have been seen in Europe and the USA with differences in the severity of the disease. Properties The Ectromelia virus belongs to the genus Orthopoxvirus of the family Poxvir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Australians
Australians, colloquially known as Aussies, are the citizenship, citizens, nationality, nationals and individuals associated with the country of Australia. This connection may be residential, legal, historical or ethno-cultural. For most Australians, these connections exist and are collectively the source of their being Australian. Australian law does not provide for any racial or ethnic component of nationality, instead relying on Australian nationality law, citizenship as a legal status, though the Constitutional framers considered the Commonwealth to be "a home for Australians and the British race alone", as well as a "Christian Commonwealth". Since the postwar period, Australia has pursued an official policy of multiculturalism and has the List of sovereign states and dependent territories by immigrant population, world's eighth-largest immigrant population, Immigration to Australia, with immigrants accounting for 30 percent of the population in 2019. Between European colo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
