Pork–cat Syndrome
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Pork–cat Syndrome
Pork–cat syndrome is an allergy to pork, usually after adolescence, that is related to cat allergy. Although first described in 1994, it was first documented in the U.S. by Scott Commins and Thomas Platts-Mills during their research on alpha-gal allergy. It is called "pork–cat syndrome" because it is a cross-reactivity where an allergy to cat serum albumin (protein made by a cat's liver) cross-reacts with pork albumin and "can lead to severe or even fatal allergic reactions on occasions when pork is consumed." In its 1994 description, the subjects studied that were suffering from the allergy were predominantly female, and only 1 out of the 5 observed were male. See also * Allergy to cats * Alpha-gal syndrome (mammal meat allergy) * List of allergies A list is a set of discrete items of information collected and set forth in some format for utility, entertainment, or other purposes. A list may be memorialized in any number of ways, including existing only in the mind o ...
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Immunology
Immunology is a branch of biology and medicine that covers the study of Immune system, immune systems in all Organism, organisms. Immunology charts, measures, and contextualizes the Physiology, physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (such as Autoimmune disease, autoimmune diseases, Hypersensitivity, hypersensitivities, immune deficiency, and transplant rejection); and the physical, chemical, and physiological characteristics of the components of the immune system ''in vitro'', ''In situ#Biology and biomedical engineering, in situ'', and ''in vivo''. Immunology has applications in numerous disciplines of medicine, particularly in the fields of organ transplantation, oncology, rheumatology, virology, bacteriology, parasitology, psychiatry, and dermatology. The term was coined by Russian biologist Ilya Ilyich Mechnikov, who advanced studies on immunology and received the Nob ...
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Food Allergy
A food allergy is an abnormal immune system, immune response to food. The symptoms of the allergic reaction may range from mild to severe. They may include pruritus, itchiness, swelling of the tongue, vomiting, diarrhea, hives, trouble breathing, or low blood pressure. This typically occurs within minutes to several hours of exposure. When the symptoms are severe, it is known as anaphylaxis. A food intolerance and food poisoning are separate conditions, not due to an immune response. Common foods involved include cow's milk, peanuts, egg as food, eggs, shellfish, fish as food, fish, tree nuts, soybean, soy, wheat, and sesame. The common allergies vary depending on the country. Risk factors include a family history of allergies, vitamin D deficiency, obesity, and high levels of cleanliness. Allergies occur when immunoglobulin E (IgE), part of the body's immune system, binds to food molecules. A protein in the food is usually the problem. This triggers the release of inflammator ...
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Pork
Pork is the culinary name for the meat of the pig (''Sus domesticus''). It is the most commonly consumed meat worldwide, with evidence of pig animal husbandry, husbandry dating back to 8000–9000 BCE. Pork is eaten both freshly cooked and preserved; Curing (food preservation), curing extends the shelf life of pork products. Ham, Gammon (meat), gammon, bacon, and sausage, pork sausage are examples of preserved pork. Charcuterie is the branch of cooking devoted to prepared meat products, many from pork. Pork is the most popular meat in the Western world, particularly in Central Europe. It is also very popular in East Asia, East and Southeast Asia (Mainland Southeast Asia, Philippines, Singapore, and East Timor). The meat is highly prized in Asian cuisines, especially in China (including Hong Kong) and Northeast India, for its fat content and texture. Some religions and cultures Religious restrictions on the consumption of pork, prohibit pork consumption, notably Islami ...
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Adolescence
Adolescence () is a transitional stage of human Developmental biology, physical and psychological Human development (biology), development that generally occurs during the period from puberty to adulthood (typically corresponding to the age of majority). Adolescence is usually associated with the Teenager (word), teenage years, but its physical, psychological or cultural expressions may begin earlier or end later. Puberty typically begins during preadolescence, particularly in females. Physical growth (particularly in males) and cognitive development can extend past the teens. Age provides only a rough marker of adolescence, and scholars have not agreed upon a precise definition. Some definitions start as early as 10 and end as late as 30. The World Health Organization definition officially designates adolescence as the phase of life from ages 10 to 19. Biological development Puberty in general Puberty is a period of several years in which rapid physical growth and psycholog ...
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Thomas Platts-Mills
Thomas Alexander Evelyn Platts-Mills, FRS (born 1941, Colchester), son of British member of parliament and barrister John Platts-Mills, is a British allergy researcher and director of the Division of Allergy and Clinical Immunology at the University of Virginia School of Medicine. Platts-Mills was educated at University College London. He then went to Balliol College, Oxford and St. Thomas' Hospital Medical School, received his PhD from London University, and completed a fellowship at Johns Hopkins University under the tutelage of Kimishige Ishizaka. He became a member of the Royal College of Physicians in 1971. From 1975 to 1982, he worked in Britain for the Medical Research Council. Since 1982 he has worked at the University of Virginia where he has been Professor of Medicine and Microbiology and, since 1993, head of the Division of Allergy and Clinical Immunology. He served as President of the American Academy of Allergy, Asthma, and Immunology (AAAAI) from March 2006 to M ...
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Alpha-gal Allergy
Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002. Symptoms of the allergy vary greatly between individuals and include rash, hives, nausea or vomiting, difficulty breathing, drop in blood pressure, dizziness or faintness, diarrhea, severe stomach pain, and possible anaphylaxis. Alpha-gal allergy is a reaction to the carbohydrate galactose-alpha-1,3-galactose ("alpha-gal"), whereby the body is overloaded with immunoglobulin E (IgE) antibodies on exposure to the carbohydrate. Anti-gal is a human natural antibody that interacts specifically with the mammalian carbohydrate structure gal alpha 1-3Gal beta 1-4GlcNAc-R (the alpha-galactosyl epitope). The alpha-gal molecule is found in all mammals except catarrhines (apes and Old World m ...
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Cross-reactivity
Cross-reactivity, in a general sense, is the reactivity of an observed agent which initiates reactions outside the main reaction expected. This has implications for any kind of test or assay, including diagnostic tests in medicine, and can be a cause of false positives. In immunology, the definition of cross-reactivity refers specifically to the reaction of the immune system to antigens. There can be cross-reactivity between the immune system and the antigens of two different pathogens, or between one pathogen and proteins on non-pathogens, which in some cases can be the cause of allergies. In medical testing In medical tests, including rapid diagnostic tests, cross-reactivity can be either confounding or helpful, depending on the instance. An example of confounding that yields a false positive error is in a latex fixation test when agglutination occurs with another antigen rather than the antigen of interest. An example of helpful cross-reactivity is in heterophile antibody ...
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Serum Albumin
Serum albumin, often referred to simply as blood albumin, is an albumin (a type of globular protein) found in vertebrate blood. Human serum albumin is encoded by the ''ALB'' gene. Other mammalian forms, such as bovine serum albumin, are chemically similar. Serum albumin is produced by the liver, occurs dissolved in blood plasma and is the most abundant blood protein in mammals. Albumin is essential for maintaining the oncotic pressure needed for proper distribution of body fluids between blood vessels and body tissues; without albumin, the high pressure in the blood vessels would force more fluids out into the tissues. It also acts as a plasma carrier by non-specifically binding several hydrophobic steroid hormones and as a transport protein for hemin and fatty acids. Too much or too little circulating serum albumin may be harmful. Albumin in the urine usually denotes the presence of kidney disease. Occasionally albumin appears in the urine of normal persons following ...
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Liver
The liver is a major metabolic organ (anatomy), organ exclusively found in vertebrates, which performs many essential biological Function (biology), functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of various proteins and various other Biochemistry, biochemicals necessary for digestion and growth. In humans, it is located in the quadrants and regions of abdomen, right upper quadrant of the abdomen, below the thoracic diaphragm, diaphragm and mostly shielded by the lower right rib cage. Its other metabolic roles include carbohydrate metabolism, the production of a number of hormones, conversion and storage of nutrients such as glucose and glycogen, and the decomposition of red blood cells. Anatomical and medical terminology often use the prefix List of medical roots, suffixes and prefixes#H, ''hepat-'' from ἡπατο-, from the Greek language, Greek word for liver, such as hepatology, and hepatitis The liver is also an accessory digestive ...
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Allergy To Cats
Allergies to cats, a type of animal allergy, is one of the most common allergies experienced by humans. Among the eight known cat allergens, the most prominent allergen is secretoglobin Fel d 1, which is produced in the anal glands, salivary glands, and, mainly, in sebaceous glands of cats, and is ubiquitous in the United States, even in households without cats. Due to cats' grooming habits, the saliva is distributed to other areas of the animal, such as the hair and skin, increasing the impact of the allergen. The second most common is Fel d 2; this type is triggered by airborne dead skin flakes (dander) and their presence in the smell of cat urine. Allergic symptoms associated with cats include coughing, wheezing, chest tightening, itching, nasal congestion, rash, watery eyes, sneezing, chapped lips, and similar symptoms. In worst-case scenarios, allergies to cats can develop into severe respiratory symptoms such as rhinitis and mild to severe forms of asthma. Despite these sy ...
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Alpha-gal Syndrome
Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002. Symptoms of the allergy vary greatly between individuals and include rash, hives, nausea or vomiting, difficulty breathing, drop in blood pressure, dizziness or faintness, diarrhea, severe stomach pain, and possible anaphylaxis. Alpha-gal allergy is a reaction to the carbohydrate galactose-alpha-1,3-galactose ("alpha-gal"), whereby the body is overloaded with immunoglobulin E (IgE) antibodies on exposure to the carbohydrate. Anti-gal is a human natural antibody that interacts specifically with the mammalian carbohydrate structure gal alpha 1-3Gal beta 1-4GlcNAc-R (the alpha-galactosyl epitope). The alpha-gal molecule is found in all mammals except catarrhines (apes and Old World ...
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List Of Allergies
A list is a set of discrete items of information collected and set forth in some format for utility, entertainment, or other purposes. A list may be memorialized in any number of ways, including existing only in the mind of the list-maker, but lists are frequently written down on paper, or maintained electronically. Lists are "most frequently a tool", and "one does not ''read'' but only ''uses'' a list: one looks up the relevant information in it, but usually does not need to deal with it as a whole".Lucie Doležalová,The Potential and Limitations of Studying Lists, in Lucie Doležalová, ed., ''The Charm of a List: From the Sumerians to Computerised Data Processing'' (2009). Purpose It has been observed that, with a few exceptions, "the scholarship on lists remains fragmented". David Wallechinsky, a co-author of '' The Book of Lists'', described the attraction of lists as being "because we live in an era of overstimulation, especially in terms of information, and lists help us ...
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