Phossy Jaw
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Phossy Jaw
Phossy jaw, formally known as phosphorus necrosis of the jaw, was an occupational disease affecting those who worked with white phosphorus (also known as ''yellow phosphorus'') without proper safeguards. It is also likely to occur as the result of use of chemical weapons that contain white phosphorus. It was most commonly seen in workers in the matchstick industry in the 19th and early 20th centuries. It was caused by white phosphorus vapor, which destroys the bones of the jaw. Modern occupational hygiene practices have since eliminated the working conditions that caused this disease. Symptoms Those with phossy jaw would usually begin suffering painful toothaches and swelling of the gums. The pain was characterized as "persistent yet progressive ... spreading to neighboring teeth and jawbone". Over time, pus formation developed penetrating the oral mucosa with the formation of fistula, tooth loss, and recurrent abscesses. Further progression led to the formation of sequestrum ...
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Match Factory Worker With Phossy Jaw
A match is a tool for starting a fire. Typically, matches are made of small wooden sticks or stiff paper. One end is coated with a material that can be ignited by friction generated by striking the match against a suitable surface. Wooden matches are packaged in matchboxes, and paper matches are partially cut into rows and stapled into matchbooks. The coated end of a match, known as the match "head", consists of a bead of active ingredients and binder, often colored for easier inspection. There are two main types of matches: safety matches, which can be struck only against a specially prepared surface, and strike-anywhere matches, for which any suitably frictional surface can be used. Etymology The word ''match'' derives from Old French ''mèche'', referring to the wick of a candle. Historically, the term ''match'' referred to lengths of cord (later cambric) impregnated with chemicals, and allowed to burn continuously. These were used to light fires and fire guns (see matchloc ...
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Grand Duchy Of Finland
The Grand Duchy of Finland was the predecessor state of modern Finland. It existed from 1809 to 1917 as an Autonomous region, autonomous state within the Russian Empire. Originating in the 16th century as a titular grand duchy held by the Monarchy of Sweden, King of Sweden, the country became autonomous after its annexation by Russia in the Finnish War of 1808–1809. The Grand Duke of Finland was the House of Romanov, Romanov Emperor of Russia, represented by the Governor-General of Finland, Governor-General. Due to the governmental structure of the Russian Empire and Finnish initiative, the Grand Duchy's autonomy expanded until the end of the 19th century. The Senate of Finland, founded in 1809, became the most important governmental organ and the precursor to the modern Government of Finland, the Supreme Court of Finland, and the Supreme Administrative Court of Finland. Economic, social and political changes in the Grand Duchy of Finland paralleled those in the Russian Empire ...
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Intravenous
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water per os, by mouth. It may also be used to administer pharmaceutical drug, medications or other medical therapy such as blood transfusion, blood products or electrolytes to correct electrolyte imbalances. Attempts at providing intravenous therapy have been recorded as early as the 1400s, but the practice did not become widespread until the 1900s after the development of techniques for safe, effective use. The intravenous route is the fastest way to deliver medications and fluid replacement throughout the body as they are introduced directly into the circulatory system and thus quickly distributed. For this reason, the intravenous route ...
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Cancer
Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible Signs and symptoms of cancer, signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in defecation, bowel movements. While these symptoms may indicate cancer, they can also have other causes. List of cancer types, Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor Diet (nutrition), diet, sedentary lifestyle, lack of physical activity or Alcohol abuse, excessive alcohol consumption. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. infectious causes of cancer, Infection with specific viruses, bacteria and parasites is an environmental factor cau ...
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Bisphosphonate
Bisphosphonates are a class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases. They are the most commonly prescribed to treat osteoporosis. Evidence shows that they reduce the risk of fracture in post-menopausal women with osteoporosis. Bone tissue undergoes constant remodeling and is kept in balance (homeostasis) by osteoblasts creating bone and osteoclasts destroying bone. Bisphosphonates inhibit the digestion of bone by encouraging osteoclasts to undergo apoptosis, or cell death, thereby slowing bone loss. The uses of bisphosphonates include the prevention and treatment of osteoporosis, Paget's disease of bone, bone metastasis (with or without hypercalcemia), multiple myeloma, primary hyperparathyroidism, osteogenesis imperfecta, fibrous dysplasia, and other conditions that exhibit bone fragility. Chemical structure and mechanistic aspects The term bisphosphonate refers to the presence two phosphonate () groups. The ...
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Medication Related Osteonecrosis Of The Jaw
Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in many ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the medical prescription) from over-the-counter drugs (those that consumers can order for themselves). Medicines may be classified by mode of action, route of administration, biological system affected, or therapeutic effects. The World Health Organization keeps a list of essential medicines. Drug discovery and drug development are complex and expensive endeavors undertaken by pharmaceutical companies, academic scientists, and governments. As a result o ...
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