Neoflavones
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Neoflavones
Neoflavonoids are a class of polyphenolic compounds. While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, neoflavonoids have the 4-phenylchromen backbone with no hydroxyl group substitution at position 2. Types Neoflavonoids include 4-arylcoumarins (neoflavones), 4-arylchromanes, dalbergiones and dalbergiquinols. * Neoflavones are derived from the 4-phenylcoumarin (or 4-aryl-coumarin) backbone (C15H12O2). The first neoflavone isolated from natural sources was calophyllolide from ''Calophyllum inophyllum'' seeds (1951). It is also known to found in bark and timber of Sri Lankan endemic plant ''Mesua thwaitesii''. * Neoflavenes possess the 4-phenylchromen backbone (C15H10O2). Dalbergichromene, extracted from the stem-bark and heartwood of ''Dalbergia sissoo'', is an example of such compounds Other examples * Coutareagenin (5-hydroxy-7-methoxy-4-(3,4-dihydroxyphenyl)-2H-benzo-1-pyran-2-on) found in ''Hintonia latiflora'' * Dalbergin * Nivetin isolated ...
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Neoflavonoid
Neoflavonoids are a class of polyphenolic compounds. While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, neoflavonoids have the 4-phenylchromen backbone with no hydroxyl group substitution at position 2. Types Neoflavonoids include 4-arylcoumarins (neoflavones), 4-arylchromanes, dalbergiones and dalbergiquinols. * Neoflavones are derived from the 4-phenylcoumarin (or 4-aryl-coumarin) backbone (C15H12O2). The first neoflavone isolated from natural sources was calophyllolide from ''Calophyllum inophyllum'' seeds (1951). It is also known to found in bark and timber of Sri Lankan endemic plant '' Mesua thwaitesii''. * Neoflavenes possess the 4-phenylchromen backbone (C15H10O2). Dalbergichromene, extracted from the stem-bark and heartwood of ''Dalbergia sissoo ''Dalbergia sissoo'', known commonly as North Indian rosewood or ''shisham'', is a fast-growing, hardy, deciduous rosewood tree native to the Indian subcontinent and southern Iran. ''D. sissoo'' ...
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4-phenylcoumarin
Neoflavonoids are a class of polyphenolic compounds. While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, neoflavonoids have the 4-phenylchromen backbone with no hydroxyl group substitution at position 2. Types Neoflavonoids include 4-arylcoumarins (neoflavones), 4-arylchromanes, dalbergiones and dalbergiquinols. * Neoflavones are derived from the 4-phenylcoumarin (or 4-aryl-coumarin) backbone (C15H12O2). The first neoflavone isolated from natural sources was calophyllolide from ''Calophyllum inophyllum'' seeds (1951). It is also known to found in bark and timber of Sri Lankan endemic plant '' Mesua thwaitesii''. * Neoflavenes possess the 4-phenylchromen backbone (C15H10O2). Dalbergichromene, extracted from the stem-bark and heartwood of ''Dalbergia sissoo ''Dalbergia sissoo'', known commonly as North Indian rosewood or ''shisham'', is a fast-growing, hardy, deciduous rosewood tree native to the Indian subcontinent and southern Iran. ''D. sissoo'' ...
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Coumarin
Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered heterocycle that shares two carbons with the benzene ring. It can be placed in the benzopyrone chemical class and considered as a lactone. Coumarin is a colorless crystalline solid with a sweet odor resembling the scent of vanilla and a bitter taste. It is found in many plants, where it may serve as a chemical defense against predators. By inhibiting synthesis of vitamin K, a related compound is used as the prescription drug warfarin – an anticoagulant – to inhibit formation of blood clots, deep vein thrombosis, and pulmonary embolism. Etymology Coumarin is derived from ''coumarou'', the French word for the tonka bean. The word ''tonka'' for the tonka bean is taken from the Galibi (Carib) tongue spoken by natives of French Gui ...
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Flavonoid
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids * isoflavonoids, derived from 3-phenyl chromen-4-one (3-phenyl-1,4- benzopyrone) structure *neoflavonoids, derived from 4-phenyl coumarine (4-phenyl-1,2- benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins (flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to descri ...
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Calophyllum Inophyllum
''Calophyllum inophyllum'' is a large evergreen plant, commonly called tamanu, oil-nut, mastwood, beach calophyllum or beautyleaf. It is native to tropical Asia and Wallacea. Due to its importance as a source of timber for the traditional shipbuilding of large outrigger ships, it has been spread in prehistoric times by the migrations of the Austronesian peoples to the islands of Oceania and Madagascar, along with other members of the genus ''Calophyllum''. It has since been naturalized in regions in the East African coast. It is also a source of the culturally important tamanu oil. Names ''Calophyllum inophyllum'' is also known as Alexandrian laurel balltree, beach touriga, Borneo-mahogany, Indian doomba oiltree, Indian-laurel, laurelwood, red poon, satin touriga, and tacamahac-tree. In Island Southeast Asia and Oceania, they are also commonly known as bintangur, bitaog, tamanu, or kamani. In India it is known as Polanga (ପୋଲାଙ୍ଗ) in Odia, Punnag (पुन ...
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Mesua Thwaitesii
''Mesua thwaitesii'', is a plant species in the family Calophyllaceae. It is endemic to Sri Lanka, where Sinhalese people called "Diya Nā - දිය නා". The plant is highly valuable as a medicinal plant within the country. Chemistry Timber, seeds and bark of ''Mesua thwaitesii'' is known to have Xanthones and 4-phenylcoumarins. Taxonomical controversy ''Mesua ferrea ''Mesua ferrea'', the Ceylon ironwood, or cobra saffron, is a species in the family Calophyllaceae. This slow-growing tree is named after the heaviness and hardness of its timber. It is widely cultivated as an ornamental due to its graceful sh ...'' is a complex species and has recently been split into several species and varieties. A.J.G.H. Kostermans and Gunatilleke et al. call the tree described in the Wikipedia article '' Mesua nagassarium''. Kostermans lists several subspecies of ''Mesua nagassarium''. These authors list ''Mesua ferrea'' as a separate species that is endemic to Sri Lanka and is a ...
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Dalbergichromene
Dalbergichromene is a neoflavene, a type of neoflavonoid (a polyphenolic compound). Dalbergichromene can be extracted from the stem-bark and heartwood of ''Dalbergia sissoo''. It has also been synthesized from vanillin Vanillin is an organic compound with the molecular formula . It is a phenolic aldehyde. Its functional groups include aldehyde, hydroxyl, and ether. It is the primary component of the extract of the vanilla bean. Synthetic vanillin is now u .... References Neoflavonoids Resorcinol ethers {{Aromatic-stub ...
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Dalbergia Sissoo
''Dalbergia sissoo'', known commonly as North Indian rosewood or ''shisham'', is a fast-growing, hardy, deciduous rosewood tree native to the Indian subcontinent and southern Iran. ''D. sissoo'' is a large, crooked tree with long, leathery leaves and whitish or pink flowers. Description ''Dalbergia sissoo'' is a medium to large deciduous tree with a light crown, which reproduces by seeds and suckers. It can grow up to in height and in diameter, but is usually smaller. Trunks are often crooked when grown in the open. Leaves are leathery, alternate, pinnately compound, and about long. Flowers are whitish to pink, fragrant, nearly sessile, up to long, and in dense clusters in length. Pods are oblong, flat, thin, strap-like, long, wide, and light brown. They contain one to five flat, bean-shaped seeds, long. They have a long taproot and numerous surface roots that produce suckers. Young shoots are downy and drooping; established stems have light brown to dark gray bark, up ...
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Hintonia Latiflora
''Hintonia latiflora'' is a plant species in the genus '' Hintonia''. ''Hintonia latiflora'' contains the neoflavonoid Neoflavonoids are a class of polyphenolic compounds. While flavonoids (in the narrow sense) have the 2-phenylchromen-4-one backbone, neoflavonoids have the 4-phenylchromen backbone with no hydroxyl group substitution at position 2. Types Neoflav ... coutareagenin (5-hydroxy-7-methoxy-4-(3,4-dihydroxyphenyl)-2H-benzo-1-pyran-2-ol), an antidiabetic active substance. References External links Catesbaeeae Taxa named by Martín Sessé y Lacasta Taxa named by José Mariano Mociño Taxa named by Alphonse Pyramus de Candolle {{Cinchonoideae-stub ...
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