Novel Coronavirus
Novel coronavirus (nCoV) is a provisional name given to coronaviruses of medical significance before a permanent name is decided upon. Although coronaviruses are endemic in humans and infections normally mild, such as the common cold (caused by human coronaviruses in ~15% of cases), cross-species transmission has produced some unusually virulent strains which can cause viral pneumonia and in serious cases even acute respiratory distress syndrome and death. Species The following viruses could initially be referred to as "novel coronavirus", before being formally named: All four viruses are part of the ''Betacoronavirus'' genus within the coronavirus family. Etymology The word "novel" indicates a "new pathogen of a previously known type" (''i.e.'' known family) of virus. Use of the word conforms to best practices for naming new infectious diseases published by the World Health Organization (WHO) in 2015. Historically, diseases have sometimes been named after locations, indivi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Coronaviridae
''Coronaviridae'' is a family (biology), family of Viral envelope, enveloped, positive-strand RNA viruses which infect fish, amphibians, birds, and mammals. The group includes the subfamilies ''Letovirinae,'' ''Orthocoronavirinae'', and ''Pitovirinae''. The members of the subfamily ''Orthocoronavirinae'' are known as Coronavirus, coronaviruses. The viral genome is 26–32 kilobases in length. The particles are typically decorated with large (~20 nm), club- or petal-shaped surface projections (the "peplomers" or "spikes"), which in electron micrographs of spherical particles create an image reminiscent of the solar corona. Virology The 5' and 3' ends of the genome have a Five-prime cap, cap and poly(A) tract, respectively. The viral envelope, obtained by budding through membranes of the endoplasmic reticulum (ER) or Golgi apparatus, invariably contains two virus-specified glycoprotein species, known as the spike (S) and membrane (M) proteins. The coronavirus spike protein, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 can vary but often include fever, fatigue, cough, breathing difficulties, anosmia, loss of smell, and ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure, shock (circulatory), shock, or organ dysfunction, multiorgan dysfunction). Older people have a higher risk of developing severe symptoms. Some complicati ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Severe Acute Respiratory Syndrome
Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the virus SARS-CoV-1, the first identified strain of the SARS-related coronavirus. The first known cases occurred in November 2002, and the syndrome caused the 2002–2004 SARS outbreak. In 2004, Xue Wu Zhang and Yee Leng Yap found that the Spike 2 (S2) protein of SARS is structurally similar to HIV-1 gp41 subunit, suggesting an analogous membrane fusion mechanism between the two. In the 2010s, Chinese scientists traced the virus through the intermediary of Asian palm civets to cave-dwelling horseshoe bats in Xiyang Yi Ethnic Township, Yunnan.The locality was referred to be "a cave in Kunming" in earlier sources because the Xiyang Yi Ethnic Township is administratively part of Kunming, though 70 km apart. Xiyang was identified on * For an earlier interview of the researchers about the locality of the caves, see: SARS was a relatively rare disease; at the end of the epid ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Masked Palm Civet
The masked palm civet (''Paguma larvata''), also called the gem-faced civet or Himalayan palm civet, is a viverrid species native to the Indian subcontinent and Southeast Asia. It has been listed as least concern on the IUCN Red List since 2008 as it occurs in many protected areas, is tolerant to some degree of habitat modification, and widely distributed with presumed large populations that are unlikely to be declining. The genus ''Paguma'' was first named and described by John Edward Gray in 1831. All described forms are regarded as a single species. In 2003, masked palm civets at a wildlife market in China were found to have been infected with the severe acute respiratory syndrome coronavirus. Characteristics The masked palm civet's fur is grayish to ochraceous, black on the head, shoulders and neck, and blackish brown on the tail and feet. It has a white blaze on the forehead; white marks above and below the eyes extend to the ears, forming a half-collar. In morpho ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Severe Acute Respiratory Syndrome Coronavirus 1
Severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1), previously known as severe acute respiratory syndrome coronavirus (SARS-CoV), is a strain of coronavirus that causes severe acute respiratory syndrome (SARS), the respiratory illness responsible for the 2002–2004 SARS outbreak. It is an Viral envelope, enveloped, Sense (molecular biology), positive-sense, RNA, single-stranded RNA virus that infects the Epithelium, epithelial cells within the lungs. The virus enters the host cell by binding to angiotensin-converting enzyme 2. It infects humans, bats, and Paradoxurinae, palm civets. The SARS-CoV-1 outbreak was largely brought under control by simple public health measures. Testing people with symptoms (fever and respiratory problems), isolating and quarantining suspected cases, and restricting travel all had an effect. SARS-CoV-1 was most transmissible when patients were sick, so its spread could be effectively suppressed by isolating patients with symptoms. On Ap ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Coronavirus Respiratory Syndrome
Coronavirus diseases are caused by viruses in the coronavirus subfamily, a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, the group of viruses cause respiratory tract infections that can range from mild to lethal. Mild illnesses in humans include some cases of the common cold (which is also caused by other viruses, predominantly rhinoviruses), while more lethal varieties can cause SARS, MERS and COVID-19. As of 2021, 45 species are registered as coronaviruses, whilst 11 diseases have been identified, as listed below. Coronaviruses are known for their shape resembling a stellar corona, such as that of the Sun visible during a total solar eclipse; ''corona'' is derived . It was coined by Tony Waterson (professor of virology at St Thomas' Hospital) in a meeting with his colleagues June Almeida and David Tyrrell, the founding fathers of coronavirus studies, and was first used in a ''Nature'' article in 1968, with approval by the Intern ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Common Cold
The common cold, or the cold, is a virus, viral infectious disease of the upper respiratory tract that primarily affects the Respiratory epithelium, respiratory mucosa of the human nose, nose, throat, Paranasal sinuses, sinuses, and larynx. Signs and symptoms may appear in as little as two days after exposure to the virus. These may include coughing, sore throat, rhinorrhea, runny nose, Sneeze, sneezing, headache, fatigue, and fever. People usually recover in seven to ten days, but some symptoms may last up to three weeks. Occasionally, those with other health problems may develop pneumonia. Well over 200 virus strains are implicated in causing the common cold, with rhinoviruses, coronaviruses, Adenoviridae, adenoviruses and enteroviruses being the most common. They spread through the air or indirectly through contact with objects in the environment, followed by transfer to the mouth or nose. Risk factors include going to child care facilities, Sleep deprivation, not sleepin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Mouse
A mouse (: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus''). Mice are also popular as pets. In some places, certain kinds of Apodemus, field mice are locally common. They are known to invade homes for food and shelter. Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term ''mouse'' if it is smaller, or ''rat'' if it is larger. The common terms ''rat'' and ''mouse'' are not Taxonomy (biology), taxonomically specific. Typical mice are classified in the genus ''Mus (genus), Mus'', but the term ''mouse'' is not confined to members of ''Mus'' and can also apply to species from other genera such as the deer mouse, deer mouse (''Peromyscus''). Fancy mouse, Domestic mice sold as pets often differ substantially in size f ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Human Coronavirus HKU1
Human coronavirus HKU1 (HCoV-HKU1, ''Betacoronavirus hongkonense'') is a species of coronavirus in humans and animals. It causes an upper respiratory disease with symptoms of the common cold, but can advance to pneumonia and bronchiolitis. It was first discovered in January 2004 from one man in Hong Kong. Subsequent research revealed it has global distribution and earlier genesis. The virus is an Viral envelope, enveloped, Sense (molecular biology), positive-sense, RNA, single-stranded RNA virus which enters its host cell by binding to the N-Acetylneuraminic acid, N-acetyl-9-O-acetylneuraminic acid receptor. It has the Hemagglutinin esterase (HE) gene, which distinguishes it as a member of the genus ''Betacoronavirus'' and subgenus ''Embecovirus''. History HCoV-HKU1 was first detected in January 2004, in a 71-year-old man who was hospitalized due to acute respiratory distress syndrome and radiographically confirmed bilateral pneumonia. The man had recently returned to Hong Kong f ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Middle East Respiratory Syndrome
Middle East respiratory syndrome (MERS) is a viral respiratory infection caused by '' Middle East respiratory syndrome–related coronavirus'' (MERS-CoV). Symptoms may range from none, to mild, to severe depending on age and risk level. Typical symptoms include fever, cough, diarrhea, and shortness of breath. The disease is typically more severe in those with other health problems. The first case was identified in June 2012 by Egyptian physician Ali Mohamed Zaki at the Dr. Soliman Fakeeh Hospital in Jeddah, Saudi Arabia, and most cases have occurred in the Arabian Peninsula. Over 2,600 cases have been reported as of January 2021, including 45 cases in the year 2020. About 35% of those who are diagnosed with the disease die from it. Larger outbreaks have occurred in South Korea in 2015 and in Saudi Arabia in 2018. MERS-CoV is a virus in the coronavirus family believed to be originally from bats. However, humans are typically infected from camels, either during direct ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Vespertilionidae
Vespertilionidae is a family of microbats, of the order Chiroptera, flying, insect-eating mammals variously described as the common, vesper, or simple nosed bats. The vespertilionid family is the most diverse and widely distributed of bat families, specialised in many forms to occupy a range of habitats and ecological circumstances, and it is frequently observed or the subject of research. The facial features of the species are often simple, as they mainly rely on vocally emitted echolocation. The tails of the species are enclosed by the lower flight membranes between the legs. Over 300 species are distributed all over the world, on every continent except Antarctica. It owes its name to the genus '' Vespertilio'', which takes its name from a word for bat, ', derived from the Latin term ' meaning 'evening'; they are termed "evening bats" and were once referred to as "evening birds". (The term "evening bat" also often refers more specifically to one of the species, '' Nycticeius hume ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Dromedary
The dromedary (''Camelus dromedarius''), also known as the dromedary camel, Arabian camel and one-humped camel, is a large camel of the genus '' Camelus'' with one hump on its back. It is the tallest of the three camel species; adult males stand at the shoulder, while females are tall. Males typically weigh between , and females weigh between . The dromedary's distinctive features include its long, curved neck, narrow chest, a single hump, and long hairs on the throat, shoulders, and hump. The coat is generally a shade of brown. The hump, tall or more, is made of fat bound together by fibrous tissue. The dromedary feeds on foliage and desert vegetation; several adaptations, such as the ability to tolerate losing more than 30% of its total water content, allow it to thrive in its desert habitat. Mating occurs annually and peaks in the rainy season; females bear a single calf after a gestation of 15 months. It is mainly active during daylight hours and forms herds of about 20 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |