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Modified Rankin Scale
The modified Rankin Scale (mRS) is a commonly used scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability. It has become the most widely used clinical outcome measure for stroke clinical trials. The scale was originally introduced in 1957 by Dr. John Rankin of Stobhill Hospital, Glasgow, Scotland as a 5-level scale ranging from 1 to 5. It was then modified by either van Swieten et al. or perhaps Prof. C. Warlow's group at Western General Hospital in Edinburgh for use in the UK-TIA study in the late 1980s to include the value '0' for patients who had no symptoms. As late as 2005 the scale was still being reported as ranging from 0 to 5. Somewhere between 2005 and 2008 the final change was made to add the value '6' to designate patients who had died. The modern version of modified version differs from Rankin's original scale mainly in the addition of grade 0, indicating a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Activities Of Daily Living
Activities of daily living (ADLs) is a term used in healthcare to refer to an individual's daily self-care activities. Health professionals often use a person's ability or inability to perform ADLs as a measure of their Performance status, functional status. The concept of ADLs was originally proposed in the 1950s by Sidney Katz and his team at the Benjamin Rose Hospital in Cleveland, Ohio. Since then, numerous researchers have expanded on the concept of ADLs. For instance, many indexes that assess ADLs now incorporate measures of mobility. In 1969, Lawton and Brody developed the concept of Instrumental Activities of Daily Living (IADLs) to capture the range of activities that support independent living. These are often utilized in caring for individuals with disabilities, injuries, and the elderly."Activities of Daily Living Evaluation." ''Encyclopedia of Nursing & Allied Health''. ed. Kristine Krapp. Gale Group, Inc., 2002. eNotes.com. 200Enotes Nursing Encyclopedia Accessed on: ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Stroke
Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemorrhagic, due to bleeding. Both cause parts of the brain to stop functioning properly. Signs and symptoms of stroke may include an hemiplegia, inability to move or feel on one side of the body, receptive aphasia, problems understanding or expressive aphasia, speaking, dizziness, or homonymous hemianopsia, loss of vision to one side. Signs and symptoms often appear soon after the stroke has occurred. If symptoms last less than 24 hours, the stroke is a transient ischemic attack (TIA), also called a mini-stroke. subarachnoid hemorrhage, Hemorrhagic stroke may also be associated with a thunderclap headache, severe headache. The symptoms of stroke can be permanent. Long-term complications may include pneumonia and Urinary incontinence, loss of b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Neurological
Neurology (from , "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system, using various techniques of neurotherapy. IEEE Brain (2019). "Neurotherapy: Treating Disorders by Retraining the Brain". ''The Future Neural Therapeutics White Paper''. Retrieved 23.01.2025 from: https://brain.ieee.org/topics/neurotherapy-treating-disorders-by-retraining-the-brain/#:~:text=Neurotherapy%20trains%20a%20patient's%20brain,wave%20activity%20through%20positive%20reinforcement International Neuromodulation Society, Retrieved 23 January 2025 from: https://www.neuromodulation.com/ Val Danilov I (2023). "The Origin of Natural Neurostimulation: A Narrative Review of Noninvasive Brain S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Clinical Endpoint
Clinical endpoints or clinical outcomes are outcome measures referring to occurrence of disease, symptom, sign or laboratory abnormality constituting a target outcome in clinical research trials. The term may also refer to any disease or sign that strongly motivates withdrawal of an individual or entity from the trial, then often termed a ''humane (clinical) endpoint''. The primary endpoint of a clinical trial is the endpoint for which the trial is powered. Secondary endpoints are additional endpoints, preferably also pre-specified, for which the trial may not be powered. Surrogate endpoints are trial endpoints that have outcomes that substitute for a clinical endpoint, often because studying the clinical endpoint is difficult, for example using an increase in blood pressure as a surrogate for death by cardiovascular disease, where strong evidence of a causal link exists. Scope In a general sense, a clinical endpoint is included in the entities of interest in a trial. The re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, pharmaceutical drug, drugs, medical nutrition therapy, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received institutional review board, health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small Pilot experiment, pi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Stobhill Hospital
Stobhill Hospital is located in Springburn in the north of Glasgow, Scotland. It serves the population of North Glasgow and part of East Dunbartonshire. It is managed by NHS Greater Glasgow and Clyde. History Early history Stobhill was originally a Poor Law hospital, commissioned by the Glasgow Parish Council. The design competition, which was judged by John James Burnet, was won by Glasgow architects, Thomson & Sandilands. The foundation stone was laid in September 1901 by Lord Balfour of Burleigh, the then Secretary of State for Scotland, and Stobhill Hospital was formally opened on 15 September 1904, the same day as the Western District Hospital at Oakbank in Maryhill and the Eastern District Hospital at Duke Street. The original buildings are now graded as category B listed buildings. It was built with 1,867 beds organised in eighteen two-storey red brick Nightingale ward blocks on a sprawling, campus on the edge of Springburn Park. The Hamiltonhill Branch of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Glasgow, Scotland
Glasgow is the Cities of Scotland, most populous city in Scotland, located on the banks of the River Clyde in Strathclyde, west central Scotland. It is the List of cities in the United Kingdom, third-most-populous city in the United Kingdom and the 27th-most-populous city in Europe, and comprises Wards of Glasgow, 23 wards which represent the areas of the city within Glasgow City Council. Glasgow is a leading city in Scotland for finance, shopping, industry, culture and fashion, and was commonly referred to as the "second city of the British Empire" for much of the Victorian era, Victorian and Edwardian eras. In , it had an estimated population as a defined locality of . More than 1,000,000 people live in the Greater Glasgow contiguous urban area, while the wider Glasgow City Region is home to more than 1,800,000 people (its defined functional urban area total was almost the same in 2020), around a third of Scotland's population. The city has a population density of 3,562 p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Western General Hospital
The Western General Hospital (often abbreviated to simply ‘The Western General’) is a health facility at Craigleith, Edinburgh, Scotland. It is managed by NHS Lothian. History The hospital was designed by Peddie and Kinnear and opened as the St. Cuthberts and Canongate Poorhouse in 1868, principally as a workhouse but also having some hospital functions. It was later renamed Craigleith Poorhouse. In 1915, during the First World War, the building was requisitioned by the War Office to create the 2nd Scottish General Hospital, a facility for the Royal Army Medical Corps to treat military casualties. After returning to poorhouse use in 1920 it was converted fully to hospital use in 1927. A nurses' home was added in 1935 and a pathology block was completed in 1939. It joined the National Health Service in 1948 and a new library was completed in 1979. The first Maggie's Cancer Caring Centre opened on the Western General Hospital site in 1996. In June 2012 the Medicine for th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Edinburgh
Edinburgh is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. The city is located in southeast Scotland and is bounded to the north by the Firth of Forth and to the south by the Pentland Hills. Edinburgh had a population of in , making it the List of towns and cities in Scotland by population, second-most populous city in Scotland and the List of cities in the United Kingdom, seventh-most populous in the United Kingdom. The Functional urban area, wider metropolitan area had a population of 912,490 in the same year. Recognised as the capital of Scotland since at least the 15th century, Edinburgh is the seat of the Scottish Government, the Scottish Parliament, the Courts of Scotland, highest courts in Scotland, and the Palace of Holyroodhouse, the official residence of the Monarchy of the United Kingdom, British monarch in Scotland. It is also the annual venue of the General Assembly of the Church of Scotland. The city has long been a cent ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
University Of Glasgow
The University of Glasgow (abbreviated as ''Glas.'' in Post-nominal letters, post-nominals; ) is a Public university, public research university in Glasgow, Scotland. Founded by papal bull in , it is the List of oldest universities in continuous operation, fourth-oldest university in the English-speaking world and one of Scotland's four Ancient universities of Scotland, ancient universities. Along with the universities of University of St Andrews, St Andrews, University of Aberdeen, Aberdeen, and University of Edinburgh, Edinburgh, the university was part of the Scottish Enlightenment during the 18th century. Glasgow is the List of universities in Scotland, second largest university in Scotland by total enrolment and -largest in the United Kingdom. In common with universities of the pre-modern era, Glasgow originally educated students primarily from wealthy backgrounds; however, it became a pioneer in British higher education in the 19th century by also providing for the needs o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Public Domain
The public domain (PD) consists of all the creative work to which no Exclusive exclusive intellectual property rights apply. Those rights may have expired, been forfeited, expressly Waiver, waived, or may be inapplicable. Because no one holds the exclusive rights, anyone can legally use or reference those works without permission. As examples, the works of William Shakespeare, Ludwig van Beethoven, Miguel de Cervantes, Zoroaster, Lao Zi, Confucius, Aristotle, L. Frank Baum, Leonardo da Vinci and Georges Méliès are in the public domain either by virtue of their having been created before copyright existed, or by their copyright term having expired. Some works are not covered by a country's copyright laws, and are therefore in the public domain; for example, in the United States, items excluded from copyright include the formulae of Classical mechanics, Newtonian physics and cooking recipes. Other works are actively dedicated by their authors to the public domain (see waiver) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
Death
Death is the end of life; the irreversible cessation of all biological functions that sustain a living organism. Death eventually and inevitably occurs in all organisms. The remains of a former organism normally begin to decompose shortly after death. Some organisms, such as '' Turritopsis dohrnii'', are biologically immortal; however, they can still die from means other than aging. Death is generally applied to whole organisms; the equivalent for individual components of an organism, such as cells or tissues, is necrosis. Something that is not considered an organism, such as a virus, can be physically destroyed but is not said ''to die'', as a virus is not considered alive in the first place. As of the early 21st century, 56 million people die per year. The most common reason is aging, followed by cardiovascular disease, which is a disease that affects the heart or blood vessels. As of 2022, an estimated total of almost 110 billion humans have died, or rou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] [Amazon] |
