|
Lacks
Henrietta Lacks (born Loretta Pleasant; August 1, 1920 – October 4, 1951) Note: Some sources report her birthday as August 2, 1920, vs. August 1, 1920. was an African-American woman whose cancer cells are the source of the HeLa cell line, the first immortalized human cell line and one of the most important cell lines in medical research. An immortalized cell line reproduces indefinitely under specific conditions, and the HeLa cell line continues to be a source of invaluable medical data to the present day. Lacks was the unwitting source of these cells from a tumor biopsied during treatment for cervical cancer at Johns Hopkins Hospital in Baltimore, Maryland, U.S., in 1951. These cells were then cultured by George Otto Gey, who created the cell line known as HeLa, which is still used for medical research. As was then the practice, no consent was required to culture the cells obtained from Lacks's treatment. Neither she nor her family were compensated for their extraction ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
African-American
African Americans (also referred to as Black Americans and Afro-Americans) are an Race and ethnicity in the United States, ethnic group consisting of Americans with partial or total ancestry from sub-Saharan Africa. The term "African American" generally denotes descendants of Slavery in the United States, enslaved Africans who are from the United States. While some Black immigrants or their children may also come to identify as African-American, the majority of first generation immigrants do not, preferring to identify with their nation of origin. African Americans constitute the second largest racial group in the U.S. after White Americans, as well as the third largest ethnic group after Hispanic and Latino Americans. Most African Americans are descendants of enslaved people within the boundaries of the present United States. On average, African Americans are of West Africa, West/Central Africa, Central African with some European descent; some also have Native Americans in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roanoke, Virginia
Roanoke ( ) is an independent city in the U.S. state of Virginia. At the 2020 census, the population was 100,011, making it the 8th most populous city in the Commonwealth of Virginia and the largest city in Virginia west of Richmond. It is located in the Roanoke Valley of the Roanoke Region of Virginia. Roanoke is the largest municipality in Southwest Virginia, and is the principal municipality of the Roanoke Metropolitan Statistical Area (MSA), which had a 2020 population of 315,251. It is composed of the independent cities of Roanoke and Salem, and Botetourt, Craig, Franklin, and Roanoke counties. Bisected by the Roanoke River, Roanoke is the commercial and cultural hub of much of Southwest Virginia and portions of Southern West Virginia. History Timeline * 1835 - Town of Gainesborough incorporated. * 1838 - Roanoke County created. * 1852 - Big Lick Depot built near Gainesborough; Virginia & Tennessee Railroad begins operating. * 1865 - April: Big Lick settlement sa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HeLa
HeLa (; also Hela or hela) is an immortalized cell line used in scientific research. It is the oldest and most commonly used human cell line. The line is derived from cervical cancer cells taken on February 8, 1951, named after Henrietta Lacks, a 31-year-old African-American mother of five, who died of cancer on October 4, 1951. The cell line was found to be remarkably durable and prolific, which allows it to be used extensively in scientific study. The cells from Lacks's cancerous cervical tumor were taken without her knowledge or consent, which was common practice in the United States at the time. Cell biologist George Otto Gey found that they could be kept alive, and developed a cell line. Previously, cells cultured from other human cells would only survive for a few days. Cells from Lacks's tumor behaved differently. History Origin In 1951, a patient named Henrietta Lacks was admitted to the Johns Hopkins Hospital with symptoms of irregular vaginal bleeding, and was s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cerebral Palsy
Cerebral palsy (CP) is a group of movement disorders that appear in early childhood. Signs and symptoms vary among people and over time, but include poor coordination, stiff muscles, weak muscles, and tremors. There may be problems with sensation, vision, hearing, and speaking. Often, babies with cerebral palsy do not roll over, sit, crawl or walk as early as other children of their age. Other symptoms include seizures and problems with thinking or reasoning, which each occur in about one-third of people with CP. While symptoms may get more noticeable over the first few years of life, underlying problems do not worsen over time. Cerebral palsy is caused by abnormal development or damage to the parts of the brain that control movement, balance, and posture. Most often, the problems occur during pregnancy, but they may also occur during childbirth or shortly after birth. Often, the cause is unknown. Risk factors include preterm birth, being a twin, certain infections during pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baltimore County, Maryland
Baltimore County ( , locally: or ) is the third-most populous county in the U.S. state of Maryland and is part of the Baltimore metropolitan area. Baltimore County (which partially surrounds, though does not include, the independent City of Baltimore) is part of the Northeast megalopolis, which stretches from Northern Virginia northward to Boston. Baltimore County hosts a diversified economy, with particular emphasis on education, government, and health care. As of the 2020 census, the population was 854,535. The county is home to multiple universities, including Goucher College, Stevenson University, Towson University, and University of Maryland, Baltimore County. History The name "Baltimore" derives from Cecil Calvert, 2nd Baron Baltimore (1605–1675), the proprietor of the new colony in the Province of Maryland, and the town of Baltimore in County Cork, Ireland. The earliest known documentary record of the county is dated January 12, 1659, when a writ was issued on be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pneumoencephalography
Pneumoencephalography (sometimes abbreviated PEG; also referred to as an "air study") was a common medical procedure in which most of the cerebrospinal fluid (CSF) was drained from around the brain by means of a lumbar puncture and replaced with air, oxygen, or helium to allow the structure of the brain to show up more clearly on an X-ray image. It was derived from ventriculography, an earlier and more primitive method where the air is injected through holes drilled in the skull. The procedure was introduced in 1919 by the American neurosurgeon Walter Dandy and was performed extensively until the late 1970s, when it was replaced by more-sophisticated and less-invasive modern neuroimaging techniques. Procedure Though pneumoencephalography was the single most important way of localizing brain lesions of its time, it was, nevertheless, extremely painful and generally not well tolerated by conscious patients. Pneumoencephalography was associated with a wide range of side-effects, inclu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crownsville Hospital Center
The Crownsville Hospital Center was a psychiatric hospital located in Crownsville, Maryland. It was in operation from 1911 until 2004. History Background Crownsville Hospital Center was enabled by an act of the Maryland General Assembly on April 11, 1910 as the Hospital for the Negro Insane of Maryland. This act also explicitly specified that the facility should not be located in Baltimore. On December 13, 1910, the Board of Managers purchased land which had formerly been farmed for willow and tobacco, located at Crownsville, Maryland, for the sum of $19,000. On May 23, 1910, Dr. Dan Hempeck was designated the first Superintendent. The facility was founded following a 1908 report of "The Maryland State Lunacy Commission" which stated: As early as 1899, the Maryland Lunacy Commission stated in its Annual Report: Again in its 1900 report it stated: In 1888, an article titled "The Need of An Asylum or Hospital for the Separate Care and Treatment of the Colored Insane o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing military alliances: the Allies and the Axis powers. World War II was a total war that directly involved more than 100 million personnel from more than 30 countries. The major participants in the war threw their entire economic, industrial, and scientific capabilities behind the war effort, blurring the distinction between civilian and military resources. Aircraft played a major role in the conflict, enabling the strategic bombing of population centres and deploying the only two nuclear weapons ever used in war. World War II was by far the deadliest conflict in human history; it resulted in 70 to 85 million fatalities, mostly among civilians. Tens of millions died due to genocides (including the Holocaust), starvation, ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sparrows Point, Maryland
Sparrow's Point is an unincorporated community in Baltimore County, Maryland, United States, adjacent to Dundalk. Named after Thomas Sparrow, landowner, it was the site of a very large industrial complex owned by Bethlehem Steel, known for steelmaking and shipbuilding. In its heyday in the mid-20th century, it was the largest steel mill in the world. The site of the former Bethlehem Sparrows Point Shipyard and steel mill is now renamed Tradepoint Atlantic in a revitalization program to clean up the environment and make it one of the largest ports on the East Coast of the United States. Today Sparrows Point is home to many distribution centers, fulfillment centers, training lots, storage lots, and the like, including those operated by Under Armour, Amazon, Home Depot, Volkswagen, and McCormick & Company. History Sparrow's Point was originally marshland home to Native American tribes until being granted to one Thomas Sparrow Jr. (1620 - 1674) by Cecilius Calvert, 2nd Baron Baltimo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bethlehem Steel
The Bethlehem Steel Corporation was an American steelmaking company headquartered in Bethlehem, Pennsylvania. For most of the 20th century, it was one of the world's largest steel producing and shipbuilding companies. At the height of its success and productivity, the company was a symbol of American manufacturing leadership in the world, and its decline and ultimate liquidation in the late 20th century is similarly cited as an example of America's diminished manufacturing leadership. From its founding in 1857 through its 2003 dissolution, Bethlehem Steel's headquarters and primary steel mill manufacturing facilities were based in Bethlehem, Pennsylvania in the Lehigh Valley region of the United States. The company's steel was used in the construction of many of America's largest and most famed structures. Among major buildings, Bethlehem produced steel for 28 Liberty Street, the Chrysler Building, the Empire State Building, Madison Square Garden, Rockefeller Center, and the Wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine. Both clinical and preclinical research phases exist in the pharmaceutical industry's drug development pipelines, where the clinical phase is denoted by the term ''clinical trial''. However, only part of the clinical or preclinical research is oriented towards a specific pharmaceutical purpose. The need for fundamental and mechanism-based understanding, diagnostics, medical devices, and non-pharmaceutical therapies means that pharmaceutical research i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
