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Epiblast
In amniote embryonic development, the epiblast (also known as the primitive ectoderm) is one of two distinct cell layers arising from the inner cell mass in the mammalian blastocyst, or from the blastula in reptiles and birds. It drives the embryo proper through its differentiation into the three primary germ layers, ectoderm, mesoderm and endoderm, during gastrulation. The amniotic ectoderm and extraembryonic mesoderm also originate from the epiblast. The other layer of the inner cell mass, the hypoblast, gives rise to the yolk sac. The layer surrounding the inner cell mass, the trophectoderm, gives rise to the chorion. Discovery of the epiblast The epiblast was first discovered by Christian Heinrich Pander (1794-1865), a Baltic German biologist and embryologist. With the help of anatomist Ignaz Döllinger (1770–1841) and draftsman Eduard Joseph d'Alton (1772-1840), Pander observed thousands of chicken eggs under a microscope, and ultimately discovered and describe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inner Cell Mass
The inner cell mass (ICM) or embryoblast (known as the pluriblast in marsupials) is a structure in the early development of an embryo. It is the mass of cells inside the blastocyst that will eventually give rise to the definitive structures of the fetus. The inner cell mass forms in the earliest stages of embryonic development, before implantation into the endometrium of the uterus. The ICM is entirely surrounded by the single layer of trophoblast cells of the trophectoderm. Further development The physical and functional separation of the inner cell mass from the trophectoderm (TE) is a special feature of mammalian development and is the first cell lineage specification in these embryos. Following fertilization in the oviduct, the mammalian embryo undergoes a relatively slow round of cleavages to produce an eight-cell morula. Each cell of the morula, called a blastomere, increases surface contact with its neighbors in a process called compaction. This results in a polari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endoderm
Endoderm is the innermost of the three primary germ layers in the very early embryo. The other two layers are the ectoderm (outside layer) and mesoderm (middle layer). Cells migrating inward along the archenteron form the inner layer of the gastrula, which develops into the endoderm. The endoderm consists at first of flattened cells, which subsequently become columnar. It forms the epithelial lining of multiple systems. In plant biology, endoderm corresponds to the innermost part of the cortex ( bark) in young shoots and young roots often consisting of a single cell layer. As the plant becomes older, more endoderm will lignify. Production The following chart shows the tissues produced by the endoderm. The embryonic endoderm develops into the interior linings of two tubes in the body, the digestive and respiratory tube. Liver and pancreas cells are believed to derive from a common precursor. In humans, the endoderm can differentiate into distinguishable organs after 5 w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inner Cell Mass
The inner cell mass (ICM) or embryoblast (known as the pluriblast in marsupials) is a structure in the early development of an embryo. It is the mass of cells inside the blastocyst that will eventually give rise to the definitive structures of the fetus. The inner cell mass forms in the earliest stages of embryonic development, before implantation into the endometrium of the uterus. The ICM is entirely surrounded by the single layer of trophoblast cells of the trophectoderm. Further development The physical and functional separation of the inner cell mass from the trophectoderm (TE) is a special feature of mammalian development and is the first cell lineage specification in these embryos. Following fertilization in the oviduct, the mammalian embryo undergoes a relatively slow round of cleavages to produce an eight-cell morula. Each cell of the morula, called a blastomere, increases surface contact with its neighbors in a process called compaction. This results in a polari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Ernst Von Baer
Karl Ernst Ritter von Baer Edler von Huthorn (; – ) was a Baltic German scientist and explorer. Baer was a naturalist, biologist, geologist, meteorologist, geographer, and is considered a, or the, founding father of embryology. He was a member of the Russian Academy of Sciences, a co-founder of the Russian Geographical Society, and the first president of the Russian Entomological Society, making him one of the most distinguished Baltic German scientists. Life Karl Ernst von Baer was born into the Baltic German noble Baer family ( et) in the Piep Manor ( et), Jerwen County, Governorate of Estonia (in present-day Lääne-Viru County, Estonia), as a knight by birthright. His patrilineal ancestors were of Westphalian origin and originated in Osnabrück. He spent his early childhood at Lasila manor, Estonia. He was educated at the Knight and Cathedral School in Reval (Tallinn) and the Imperial University of Dorpat (Tartu). In 1812, during his tenure at the univer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yolk Sac
The yolk sac is a membranous wikt:sac, sac attached to an embryo, formed by cells of the hypoblast layer of the bilaminar embryonic disc. This is alternatively called the umbilical vesicle by the Terminologia Embryologica (TE), though ''yolk sac'' is far more widely used. The yolk sac is one of the fetal membranes and is important in early embryonic blood supply. In humans much of it is incorporated into the primordial gut (anatomy), gut during the fourth week of embryonic development. In humans The yolk sac is the first element seen within the gestational sac during pregnancy, usually at three days gestation. The yolk sac is situated on the front (ventral) part of the embryo; it is lined by extra-embryonic endoderm, outside of which is a layer of extra-embryonic mesenchyme, derived from the epiblast. Blood is conveyed to the wall of the yolk sac by the primitive aorta and after circulating through a wide-meshed capillary plexus, is returned by the vitelline veins to the tubul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chorion
The chorion is the outermost fetal membrane around the embryo in mammals, birds and reptiles (amniotes). It is also present around the embryo of other animals, like insects and molluscs. Structure In humans and other therian mammals, the chorion is one of the fetal membranes that exist during pregnancy between the developing fetus and mother. The chorion and the amnion together form the amniotic sac. In humans it is formed by extraembryonic mesoderm and the two layers of trophoblast that surround the embryo and other membranes; the chorionic villi emerge from the chorion, invade the endometrium, and allow the transfer of nutrients from maternal blood to fetal blood. Layers The chorion consists of two layers: an outer formed by the trophoblast, and an inner formed by the extra-embryonic mesoderm. The trophoblast is made up of an internal layer of cubical or prismatic cells, the cytotrophoblast or layer of Langhans, and an external multinucleated layer, the syncytiotro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christian Heinrich Pander
Heinz Christian Pander, also Christian Heinrich Pander (Russian: Христиан Иванович Пандер; – ) was a Russian biologist and embryologist of Baltic German origin. Biography In 1817 he received his doctorate from the University of Würzburg, and spent several years (1827–1842), performing scientific research from his estate in Carnikava () on the banks of the Gauja River near Riga. In 1820 he took part in a scientific expedition to Bokhara as a naturalist. In 1826 he became a member of the Saint Petersburg Academy of Sciences. Research Pander studied the chick embryo and discovered the germ layers (i.e., three distinct regions of the embryo that give rise to the specific organ system). Because of these findings, he is considered by many to be the "founder of embryology". His work in embryology was continued by Karl Ernst von Baer (1792-1876), who expanded Pander's concept of germ layers to include all vertebrates. Pander performed important studies in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ignaz Döllinger
Ignaz Döllinger (27 May 1770 – 14 January 1841) was a German medical doctor, anatomist and physiologist and one of the first professors to understand and treat medicine as a natural science. Biography Ignaz Döllinger was born in 1770 in Bamberg, where his father was a professor at the university and physician to the Prince-Bishop. He commenced his studies in his native town (where he took a doctorate in 1794), continuing them in Würzburg, Pavia and Vienna before returning to Bamberg. Soon after gaining his doctorate in 1794, he became professor for physiology and general pathology in Bamberg, but was called to a professorship of anatomy and physiology at University of Würzburg in 1803 as the successor to the former city doctor, physiologist and natural philosopher Johann Joseph Dömling (1771–1803). In 1823 he moved to Munich (to the Academy, as the University was still in Landshut at this time). When the University finally moved to the capital, he transferred there. H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eduard Joseph D'Alton
Joseph Wilhelm Eduard d’Alton (August 11, 1772 – May 11, 1840) was a German engraver and naturalist who was a native of Aquileia (today part of Italy). He was the father of anatomist Johann Samuel Eduard d'Alton (1803–1854). Originally trained for military service, he learned in Vienna, a thorough knowledge of horses and horsemanship. He later traveled throughout Italy, the Rhineland and France, and during this time period, gained an insight in the areas of natural and art history. At University of Würzburg, Würzburg he worked closely with embryologist Heinz Christian Pander, Christian Heinrich Pander, and later on, he taught art history and architecture, architectural theory at the University of Bonn, where in 1827 he became a "full professor" of art history. From 1831 to 1840, d'Alton was a member of the Prussian Academy of Arts. One of his famous students in Bonn was Karl Marx. Eduard d'Alton is largely remembered for his anatomical and zoological engravings and etchi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypoblast
In amniote embryology, the hypoblast is one of two distinct layers arising from the inner cell mass in the mammalian blastocyst, or from the blastodisc in reptiles and birds. The hypoblast gives rise to the yolk sac. The hypoblast is a layer of cells in fish and amniote embryos. The hypoblast helps determine the embryo's body axes, and its migration determines the cell movements that accompany the formation of the primitive streak, and helps to orient the embryo, and create bilateral symmetry. The other layer of the inner cell mass, the epiblast, differentiates into the three primary germ layers, ectoderm, mesoderm, and endoderm. Structure The hypoblast lies beneath the epiblast and consists of small cuboidal cells. The hypoblast in fish (but not in birds and mammals) contains the precursors of both the endoderm and mesoderm. In birds and mammals, it contains precursors to the extraembryonic endoderm of the yolk sac. In chick embryos, early cleavage forms an area opaca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilhelm His, Sr
Wilhelm may refer to: People and fictional characters * William Charles John Pitcher, costume designer known professionally as "Wilhelm" * Wilhelm (name), a list of people and fictional characters with the given name or surname Other uses * Wilhelm (name), disambiguation page for people named Wilhelm ** Wilhelm II (1858–1941), king of Prussia and emperor of Germany from 1888 until his abdication in 1918. * Mount Wilhelm, the highest mountain in Papua New Guinea * Wilhelm Archipelago, Antarctica * Wilhelm (crater), a lunar crater * Wilhelm scream, stock sound effect used in many movies and shows See also * Wilhelm scream, a stock sound effect * SS ''Kaiser Wilhelm II'', or USS ''Agamemnon'', a German steam ship * Wilhelmus, the Dutch national anthem * William Helm William Helm (March 9, 1837 – April 10, 1919) was an American Sheep-rearing, sheep farmer and among the early pioneer settlers of Fresno County, California, Fresno County, California. He was instrumental in t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Extraembryonic Mesoderm
The mesoderm is the middle layer of the three germ layers that develops during gastrulation in the very early development of the embryo of most animals. The outer layer is the ectoderm, and the inner layer is the endoderm.Langman's Medical Embryology, 11th edition. 2010. The mesoderm forms mesenchyme, mesothelium and coelomocytes. Mesothelium lines coeloms. Mesoderm forms the muscles in a process known as myogenesis, septa (cross-wise partitions) and mesenteries (length-wise partitions); and forms part of the gonads (the rest being the gametes). Myogenesis is specifically a function of mesenchyme. The mesoderm differentiates from the rest of the embryo through intercellular signaling, after which the mesoderm is polarized by an organizing center. The position of the organizing center is in turn determined by the regions in which beta-catenin is protected from degradation by GSK-3. Beta-catenin acts as a co-factor that alters the activity of the transcription factor tcf-3 from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
