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Dosage Form Design
Pharmaceutics is the discipline of pharmacy that deals with the process of turning a new chemical entity (NCE) or old drugs into a medication to be used safely and effectively by patients. It is also called the science of dosage form design. There are many chemicals with pharmacological properties, but need special measures to help them achieve therapeutically relevant amounts at their sites of action. Pharmaceutics helps relate the formulation of drugs to their delivery and disposition in the body. Pharmaceutics deals with the formulation of a pure drug substance into a dosage form. Branches of pharmaceutics include: *Pharmaceutical formulation *Pharmaceutical manufacturing *Dispensing pharmacy *Pharmaceutical technology *Physical pharmacy *Pharmaceutical jurisprudence Pure drug substances are usually white crystalline or amorphous powders. Before the advent of medicine as a science, it was common for pharmacists to dispense drugs ''as is''. Most drugs today are administered as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacy
Pharmacy is the science and practice of discovering, producing, preparing, dispensing, reviewing and monitoring medications, aiming to ensure the safe, effective, and affordable use of medication, medicines. It is a miscellaneous science as it links health sciences with pharmaceutical sciences and natural sciences. The professional practice is becoming more clinically oriented as most of the drugs are now manufactured by pharmaceutical industries. Based on the setting, pharmacy practice is either classified as community or institutional pharmacy. Providing direct patient care in the community of institutional pharmacies is considered clinical pharmacy. The scope of pharmacy practice includes more traditional roles such as compounding and dispensing of medications. It also includes more modern services related to health care including clinical services, reviewing medications for safety and efficacy, and providing drug information. Pharmacists, therefore, are experts on drug ther ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amorphous
In condensed matter physics and materials science, an amorphous solid (or non-crystalline solid, glassy solid) is a solid that lacks the long-range order that is characteristic of a crystal. Etymology The term comes from the Greek language, Greek ''a'' ("without"), and ''morphé'' ("shape, form"). In some older articles and books, the term was used synonymously with glass. Today, "glassy solid" or "amorphous solid" is considered the overarching concept. Polymer, Polymers are often amorphous. Structure Amorphous materials have an internal structure comprising interconnected structural blocks that can be similar to the basic structural units found in the corresponding crystalline phase of the same compound. Unlike crystalline materials, however, no long-range order exists. Localized order in amorphous materials can be categorized as short or medium range order. By convention, short range order extends only to the nearest neighbor shell, typically only 1-2 atomic spacings. Medium ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutics
Pharmaceutics is the discipline of pharmacy that deals with the process of turning a new chemical entity (NCE) or old drugs into a medication to be used safely and effectively by patients. It is also called the science of dosage form design. There are many chemicals with pharmacological properties, but need special measures to help them achieve therapeutically relevant amounts at their sites of action. Pharmaceutics helps relate the formulation of drugs to their delivery and disposition in the body. Pharmaceutics deals with the formulation of a pure drug substance into a dosage form. Branches of pharmaceutics include: *Pharmaceutical formulation *Pharmaceutical manufacturing *Dispensing pharmacy *Pharmaceutical technology *Physical pharmacy *Pharmaceutical jurisprudence Pure drug substances are usually white crystalline or amorphous powders. Before the advent of medicine as a science, it was common for pharmacists to dispense drugs ''as is''. Most drugs today are administered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicholas Culpeper
Nicholas Culpeper (18 October 1616 – 10 January 1654) was an English botanist, herbalist, physician and astrologer.Patrick Curry: "Culpeper, Nicholas (1616–1654)", ''Oxford Dictionary of National Biography'' (Oxford, UK: OUP, 2004) His book ''The English Physician'' (1652, later ''Complete Herbal'', 1653 ff.) is a source of pharmaceutical and herbal lore of the time, and ''Astrological Judgement of Diseases from the Decumbiture of the Sick'' (1655) one of the most detailed works on medical astrology in Early Modern Europe. Culpeper catalogued hundreds of outdoor medicinal herbs. He scolded contemporaries for some of the methods they used in herbal medicine: "This not being pleasing, and less profitable to me, I consulted with my two brothers, and , and took a voyage to visit my mother , by whose advice, together with the help of , I at last obtained my desire; and, being warned by , a stranger in our days, to publish it to the world, I have done it." Culpeper came from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical Industry
The pharmaceutical industry discovers, develops, produces, and markets drugs or pharmaceutical drugs for use as medications to be administered to patients (or self-administered), with the aim to cure them, vaccinate them, or alleviate symptoms. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy using drug testing and marketing of drugs. The global pharmaceuticals market produced treatments worth $1,228.45 billion in 2020 and showed a compound annual growth rate (CAGR) of 1.8%. History Mid-1800s – 1945: From botanicals to the first synthetic drugs The modern era of pharmaceutical industry began with local apothecaries that expanded from their traditional role of distributing botanical drugs such as morphine and quinine to wholesale manufacture in the mid-1800s, and from discoveries resulting from applied research. Intentional drug ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacognosy
Pharmacognosy is the study of medicinal plants and other natural substances as sources of drugs. The American Society of Pharmacognosy defines pharmacognosy as "the study of the physical, chemical, biochemical, and biological properties of drugs, drug substances, or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources". Description The word "pharmacognosy" is derived from two Greek words: ', (drug), and '' gnosis'' (knowledge) or the Latin verb '' cognosco'' (', 'with', and , 'know'; itself a cognate of the Greek verb , , meaning 'I know, perceive'), meaning 'to conceptualize' or 'to recognize'. The term "pharmacognosy" was used for the first time by the Austrian physician Schmidt in 1811 and by Anotheus Seydler in 1815 in a work titled ''Analecta Pharmacognostica''. Originally—during the 19th century and the beginning of the 20th century—"pharmacognosy" was used to define the branch of medicine or commodity ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Pharmaceutical Companies
This listing is limited to those independent companies and subsidiaries notable enough to have their own articles in Wikipedia. Both going concerns and defunct firms are included, as well as firms that were part of the pharmaceutical industry at some time in their existence. Included here are companies engaged not only in pharmaceutical development, but also supply chain management and device development, including compounding pharmacies. Retail pharmacies; firms specialized in the collection, fractionation and distribution of human blood; and medical device manufacturers where the device is not related to pharmaceutical administration are not included. Entry titles have been shortened in a number of cases, so that if the article title of a company is "XYZ Pharma", for instance, the entry will appear here as "XYZ". Companies which existed as a joint venture for their entire existence are indicated by a super-script "JV", as in PerseidJV. Alphabetical listing—Active firms ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Informa Healthcare
Informa plc is a British publishing, business intelligence, and exhibitions group based in London, England. It is listed on the London Stock Exchange and is a constituent of the FTSE 100 Index. It has offices in 43 countries and around 11,000 employees. Informa owns numerous brands including CRC Press, Fan Expo HQ, Game Developers Conference, ''Lloyd's List'' (London Press Lloyd), Routledge, and Taylor & Francis. Informa acquired UBM in June 2018 as part of its strategy to expand in North America and Asia. History Informa itself was created in 1998 by the merger of IBC Group plc and LLP Group plc. Since then Informa has expanded considerably, including a 2004 merger with the publishing company Taylor & Francis and a 2005 acquisition of IIR Holdings, a human capital development company, for £768 million. In October 2006, the company was approached by Springer Science and Business Media in a takeover bid, but in early November the Informa board rejected the 630p per sh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crystalline
A crystal or crystalline solid is a solid material whose constituents (such as atoms, molecules, or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions. In addition, macroscopic single crystals are usually identifiable by their geometrical shape, consisting of flat faces with specific, characteristic orientations. The scientific study of crystals and crystal formation is known as crystallography. The process of crystal formation via mechanisms of crystal growth is called crystallization or solidification. The word ''crystal'' derives from the Ancient Greek word (), meaning both " ice" and " rock crystal", from (), "icy cold, frost". Examples of large crystals include snowflakes, diamonds, and table salt. Most inorganic solids are not crystals but polycrystals, i.e. many microscopic crystals fused together into a single solid. Polycrystals include most metals, rocks, ceramics, and ice. A third catego ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New Chemical Entity
A new chemical entity (NCE) is, according to the U.S. Food and Drug Administration, a novel, small, chemical molecule drug that is undergoing clinical trials or has received a first approval (not a new use) by the FDA in any other application submitted under section 505(b) of the Federal Food, Drug, and Cosmetic Act. A new molecular entity (NME) is a broader term that emcompasses both an NCE or an NBE (New Biological Entity). Definition An active moiety is a molecule or ion, excluding those appended portions of the molecule that cause the drug to be an ester, salt (including a salt with hydrogen or coordination bonds), or other noncovalent derivative (such as a complex, chelate, or clathrate) of the molecule, responsible for the physiological or pharmacological action of the drug substance. An NCE is a molecule developed by the innovator company in the early drug discovery stage, which after undergoing clinical trials could translate into a drug that could be a treatment for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical Jurisprudence
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell thera ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physical Pharmacy
Physical pharmacy is the branch of pharmacy that concentrates on the applications of physics and chemistry to the study of pharmacy. In other words, it is the study of the effects that dosage forms have on their environment by addressing issues at the molecular level. It emphasis on the physical characteristics and actions of the drug delivery system before the same is given to the patient. It forms the basis for design, manufacture, and distribution of drug products and serves as the foundation for the stable and proper use of medical drugs. It covers areas such as solubility, pharmacokinetics and drug delivery. Physical pharmacy serves as principles that guide the pharmaceutical developments. It also serves as a basis for the understanding of drug absorptions, distributions, metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the con ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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