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Diosgenin
Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of '' Dioscorea'' wild yam species, such as the Kokoro. The sugar-free ( aglycone) product of such hydrolysis, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. Sources It is present in detectable amounts in ''Costus speciosus'', ''Smilax menispermoidea'', '' Helicteres isora'', species of ''Paris'', '' Aletris'', ''Trigonella'', and '' Trillium'', and in extractable amounts from many species of '' Dioscorea'' – '' D. althaeoides'', '' D. colletti'', '' D. composita'', '' D. floribunda'', '' D. futschauensis'', '' D. gracillima'', '' D. hispida'', '' D. hypoglauca'', '' D. mexicana'', '' D. nipponica'', '' D. panthaica'', '' D. parviflora'', '' D. septemloba'', and '' D. zingiberensis''. Industrial uses Diosgenin is a precursor for several hormones, starting with th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Progesterone
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens and is the major progestogen in the body. Progesterone has a variety of important functions in the body. It is also a crucial metabolic intermediate in the production of other endogenous steroids, including the sex hormones and the corticosteroids, and plays an important role in brain function as a neurosteroid. In addition to its role as a natural hormone, progesterone is also used as a medication, such as in combination with estrogen for contraception, to reduce the risk of uterine or cervical cancer, in hormone replacement therapy, and in feminizing hormone therapy. It was first prescribed in 1934. Biological activity Progesterone is the most important progestogen in the body. As a potent agonist of the nuclear progesterone receptor (nPR) (wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Composita
''Dioscorea composita'', or barbasco, is a species of yam in the genus ''Dioscorea'', native to Mexico. It is notable for its role in the production of diosgenin, which is a precursor for the synthesis of hormones such as progesterone. Russell Marker developed the extraction and manufacture of hormones from ''D. mexicana'' at Syntex, starting the trade of ''D. composita'' in Mexico. Marker also discovered that the ''composita'' variety had a much higher content of diosgenin than the ''mexicana'' variety, and therefore it came to replace the latter in the production of synthetic hormones. Chemical constituents Steroidal sapogenin, diosgenin. Medicinal use It is a source of diosgenin, which is used to prepare synthetic hormones such as progesterone and cortisone. Diosgenin extracted from ''Dioscorea composita'' was instrumental in the development of the combined oral contraceptive pill in the 1960s – and also for the development of cortisone treatments of arthritis. Studie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Zingiberensis
''Dioscorea zingiberensis'', is a species of yam, a tuberous root vegetable. It has been cultivated in China for the production of diosgenin,Liu, L., Dong, Y., 375 Xiu, Z., 2010. Three-liquid-phase extraction of diosgenin and steroidal saponins from fermentation of ''Dioscorea zingibernsis'' C.H. Wright. Process Biochemistry 45, 752–756. an important pharmaceutical intermediate for the synthesis of steroid hormones. The rhizomes also produces steroidal saponins (TSS) as part of a treatment for cardiovascular disease Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, .... References zingiberensis {{monocot-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Colletti
''Dioscorea'' is a genus of over 600 species of flowering plants in the family Dioscoreaceae, native throughout the tropical and warm temperate regions of the world. The vast majority of the species are tropical, with only a few species extending into temperate climates. It was named by the monk Charles Plumier after the ancient Greek physician and botanist Dioscorides. Description Wild Yam (''Dioscorea'') is a vine that is invasive, deciduous, and herbaceous. This species is native to Asia, though, in the U.S., it is commonly found in Florida. They can grow over in length. Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores. This was used to create the first birth control pills during the 60s. In addition, some ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Septemloba
''Dioscorea'' is a genus of over 600 species of flowering plants in the family Dioscoreaceae, native throughout the tropical and warm temperate regions of the world. The vast majority of the species are tropical, with only a few species extending into temperate climates. It was named by the monk Charles Plumier after the ancient Greek physician and botanist Dioscorides. Description Wild Yam (''Dioscorea'') is a vine that is invasive, deciduous, and herbaceous. This species is native to Asia, though, in the U.S., it is commonly found in Florida. They can grow over in length. Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores. This was used to create the first birth control pills during the 60s. In addition, some '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Parviflora
''Dioscorea'' is a genus of over 600 species of flowering plants in the family Dioscoreaceae, native throughout the tropical and warm temperate regions of the world. The vast majority of the species are tropical, with only a few species extending into temperate climates. It was named by the monk Charles Plumier after the ancient Greek physician and botanist Dioscorides. Description Wild Yam (''Dioscorea'') is a vine that is invasive, deciduous, and herbaceous. This species is native to Asia, though, in the U.S., it is commonly found in Florida. They can grow over in length. Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores. This was used to create the first birth control pills during the 60s. In addition, some ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea
''Dioscorea'' is a genus of over 600 species of flowering plants in the family Dioscoreaceae, native throughout the tropical and warm temperate regions of the world. The vast majority of the species are tropical, with only a few species extending into temperate climates. It was named by the monk Charles Plumier after the ancient Greek physician and botanist Dioscorides. Description Wild Yam (''Dioscorea'') is a vine that is invasive, deciduous, and herbaceous. This species is native to Asia, though, in the U.S., it is commonly found in Florida. They can grow over in length. Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores. This was used to create the first birth control pills during the 60s. In addition, some ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Panthaica
''Dioscorea'' is a genus of over 600 species of flowering plants in the family Dioscoreaceae, native throughout the tropical and warm temperate regions of the world. The vast majority of the species are tropical, with only a few species extending into temperate climates. It was named by the monk Charles Plumier after the ancient Greek physician and botanist Dioscorides. Description Wild Yam (''Dioscorea'') is a vine that is invasive, deciduous, and herbaceous. This species is native to Asia, though, in the U.S., it is commonly found in Florida. They can grow over in length. Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores. This was used to create the first birth control pills during the 60s. In addition, so ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Nipponica
''Dioscorea'' is a genus of over 600 species of flowering plants in the family Dioscoreaceae, native throughout the tropical and warm temperate regions of the world. The vast majority of the species are tropical, with only a few species extending into temperate climates. It was named by the monk Charles Plumier after the ancient Greek physician and botanist Dioscorides. Description Wild Yam (''Dioscorea'') is a vine that is invasive, deciduous, and herbaceous. This species is native to Asia, though, in the U.S., it is commonly found in Florida. They can grow over in length. Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores. This was used to create the first birth control pills during the 60s. In addition, some '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Mexicana
''Dioscorea mexicana'', Mexican yam or ''cabeza de negro'' is a species of yam in the genus ''Dioscorea''. ''Dioscorea mexicana'' is a caudiciform dioscorea having either a partly to completely above-ground dome-shaped caudex with a thick, woody outer layer up to 3 feet (90 cm) in diameter and 8–10 inches (20 to 25 cm) in height. The caudex of ''D. mexicana'' is divided into regular polygonal plates that become protuberant with age, and separated by deep fissures. The vigorous annual vines which may reach 30 feet (9 m) long before dying back in winter, that grow up from the caudex, bear heart-shaped leaves. ''Dioscorea mexicana'' ranges from the state of San Luis Potosí in northeastern Mexico south to Panama. It is notable for its production of diosgenin, which is a precursor for the synthesis of hormones such as progesterone. Russell Marker developed the extraction and manufacture of hormones from ''D. mexicana'' at Syntex. Later the Mexican barbasco trade fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Hypoglauca
''Dioscorea'' is a genus of over 600 species of flowering plants in the family Dioscoreaceae, native throughout the tropical and warm temperate regions of the world. The vast majority of the species are tropical, with only a few species extending into temperate climates. It was named by the monk Charles Plumier after the ancient Greek physician and botanist Dioscorides. Description Wild Yam (''Dioscorea'') is a vine that is invasive, deciduous, and herbaceous. This species is native to Asia, though, in the U.S., it is commonly found in Florida. They can grow over in length. Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores. This was used to create the first birth control pills during the 60s. In addition, some ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dioscorea Gracillima
''Dioscorea'' is a genus of over 600 species of flowering plants in the family Dioscoreaceae, native throughout the tropical and warm temperate regions of the world. The vast majority of the species are tropical, with only a few species extending into temperate climates. It was named by the monk Charles Plumier after the ancient Greek physician and botanist Dioscorides. Description Wild Yam (''Dioscorea'') is a vine that is invasive, deciduous, and herbaceous. This species is native to Asia, though, in the U.S., it is commonly found in Florida. They can grow over in length. Wild yams are an important crop, as they have been used to prevent menstrual cramps, stomach cramps, and general pain for centuries. During the 1950s scientists found that the roots of wild yams contained diosgenin which is a plant-based estrogen; diosgenin is hypothesized to aid in chemical defense against herbivores. This was used to create the first birth control pills during the 60s. In addition, some '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
