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Diverticulum
In medicine or biology, a diverticulum is an outpouching of a hollow (or a fluid-filled) structure in the body. Depending upon which layers of the structure are involved, diverticula are described as being either true or false. In medicine, the term usually implies the structure is not normally present, but in embryology, the term is used for some normal structures arising from others, as for instance the thyroid diverticulum, which arises from the tongue. The word comes from Latin ''dīverticulum'', "bypath" or "byway". Classification Diverticula are described as being true or false depending upon the layers involved: *False diverticula (also known as "pseudodiverticula") do not involve muscular layers or adventitia. False diverticula, in the gastrointestinal tract for instance, involve only the submucosa and mucosa, such as Zenker's diverticulum. False diverticula are typically synonymous with pulsion diverticula, which describes the mechanism of formation as increase ...
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Meckel's Diverticulum
A Meckel's diverticulum, a true congenital diverticulum, is a slight bulge in the small intestine present at birth and a vestigial remnant of the vitelline duct. It is the most common malformation of the Human gastrointestinal tract, gastrointestinal tract and is present in approximately 2% of the population, with males more frequently experiencing symptoms. Meckel's diverticulum was first explained by Fabricius Hildanus in the sixteenth century and later named after Johann Friedrich Meckel, who described the embryological origin of this type of diverticulum in 1809. Signs and symptoms The majority of people with a Meckel's diverticulum are asymptomatic. An asymptomatic Meckel's diverticulum is called a ''silent'' Meckel's diverticulum. If symptoms do occur, they typically appear before the age of two years. The most common presenting symptom is painless rectal bleeding such as melaena-like black offensive stools, followed by intestinal obstruction, volvulus and intussusception (m ...
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Pulsion Diverticulum
A Zenker's diverticulum, also pharyngeal pouch, is a diverticulum of the mucosa of the human pharynx, just above the cricopharyngeal muscle (i.e. above the upper sphincter of the esophagus). It is a pseudo diverticulum or false diverticulum (only involving the mucosa and submucosa of the esophageal wall, not the adventitia), also known as a pulsion diverticulum. It was named in 1877 after Germany, German pathologist Friedrich Albert von Zenker. Signs and symptoms When there is excessive pressure within the lower human pharynx, pharynx, the weakest portion of the pharyngeal wall balloons out, forming a diverticulum which may reach several centimetres in diameter. While traction and pulsion mechanisms have long been deemed the main factors promoting development of a Zenker's diverticulum, current consensus considers occlusive mechanisms to be most important: uncoordinated swallowing, impaired relaxation and spasm of the cricopharyngeus muscle lead to an increase in pressure with ...
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Achalasia
Esophageal achalasia, often referred to simply as achalasia, is a failure of smooth muscle fibers to relax, which can cause the lower esophageal sphincter to remain closed. Without a modifier, "achalasia" usually refers to achalasia of the esophagus. Achalasia can happen at various points along the human gastrointestinal tract, gastrointestinal tract; achalasia of the rectum, for instance, may occur in Hirschsprung's disease. The lower esophageal sphincter is a muscle between the esophagus and stomach that opens when food comes in. It closes to avoid Gastric acid, stomach acids from coming back up. A fully understood cause to the disease is unknown, as are factors that increase the risk of its appearance. Suggestions of a Genetic disorder, genetically transmittable form of achalasia exist, but this is neither fully understood, nor agreed upon. Esophageal achalasia is an esophageal motility disorder involving the smooth muscle cell, smooth muscle layer of the esophagus and the lowe ...
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Thyroid Diverticulum
The thyroid pouch or thyroid diverticulum is the embryological structure of the second pharyngeal arch from which thyroid follicular cells derive. It grows from the floor of the pharynx. See also * Diverticulum In medicine or biology, a diverticulum is an outpouching of a hollow (or a fluid-filled) structure in the body. Depending upon which layers of the structure are involved, diverticula are described as being either true or false. In medicine, t ... References Human head and neck Embryology Thyroid {{developmental-biology-stub ...
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Zenker's Diverticulum
A Zenker's diverticulum, also pharyngeal pouch, is a diverticulum of the mucosa of the human pharynx, just above the cricopharyngeal muscle (i.e. above the upper sphincter of the esophagus). It is a pseudo diverticulum or false diverticulum (only involving the mucosa and submucosa of the esophageal wall, not the adventitia), also known as a pulsion diverticulum. It was named in 1877 after German pathologist Friedrich Albert von Zenker. Signs and symptoms When there is excessive pressure within the lower pharynx, the weakest portion of the pharyngeal wall balloons out, forming a diverticulum which may reach several centimetres in diameter. While traction and pulsion mechanisms have long been deemed the main factors promoting development of a Zenker's diverticulum, current consensus considers occlusive mechanisms to be most important: uncoordinated swallowing, impaired relaxation and spasm of the cricopharyngeus muscle lead to an increase in pressure within the distal pharynx, ...
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Killian's Triangle
Killian's dehiscence (also known as Killian's triangle) is a triangular area in the wall of the pharynx between the cricopharyngeus (upper esophageal sphincter (UES)) and thyropharyngeus (Inferior pharyngeal constrictor muscle) which are the two parts of the inferior constrictors (also see Pharyngeal pouch). It can be seen as a locus minoris resistentiae. A similar triangular area between circular fibres of the cricopharyngeus and longitudinal fibres of the esophagus is Lamier's triangle or Lamier-hackermann's area. Clinical significance It represents a potentially weak spot where a pharyngoesophageal diverticulum ( Zenker's diverticulum) is more likely to occur. Eponym It is named after the German ENT surgeon Gustav Killian Gustav Killian (2 June 1860 – 24 February 1921) was a Germans, German Laryngology, laryngologist and founder of the bronchoscopy. Life and death His father Johann Baptist Caesar Killian (1820–1889), the son of a ''städtischen Wegeaufsehers'' a .... Ref ...
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Cricopharyngeal Muscle
The inferior pharyngeal constrictor muscle is a skeletal muscle of the neck. It is the thickest of the three outer pharyngeal muscles. It arises from the sides of the cricoid cartilage and the thyroid cartilage. It is supplied by the vagus nerve (CN X). It is active during swallowing, and partially during breathing and speech. It may be affected by Zenker's diverticulum. Structure The inferior pharyngeal constrictor muscle is composed of two parts. The first part (and more superior) arises from the thyroid cartilage (thyropharyngeal part), and the second part arises from the cricoid cartilage (cricopharyngeal part). * On the ''thyroid cartilage'', it arises from the oblique line on the side of the wikt:lamina, lamina, from the surface behind this nearly as far as the posterior border and from the Inferior horn of thyroid cartilage, inferior horn of the thyroid cartilage. * From the ''cricoid cartilage'', it arises in the interval between the cricothyroid muscle in front, and the ...
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Inferior Pharyngeal Constrictor Muscle
The inferior pharyngeal constrictor muscle is a skeletal muscle of the neck. It is the thickest of the three outer pharyngeal muscles. It arises from the sides of the cricoid cartilage and the thyroid cartilage. It is supplied by the vagus nerve (CN X). It is active during swallowing, and partially during breathing and speech. It may be affected by Zenker's diverticulum. Structure The inferior pharyngeal constrictor muscle is composed of two parts. The first part (and more superior) arises from the thyroid cartilage (thyropharyngeal part), and the second part arises from the cricoid cartilage (cricopharyngeal part). * On the ''thyroid cartilage'', it arises from the oblique line on the side of the lamina, from the surface behind this nearly as far as the posterior border and from the inferior horn of the thyroid cartilage. * From the ''cricoid cartilage'', it arises in the interval between the cricothyroid muscle in front, and the articular facet for the inferior horn of ...
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Gastroenterology
Gastroenterology (from the Greek gastḗr- "belly", -énteron "intestine", and -logía "study of") is the branch of medicine focused on the digestive system and its disorders. The digestive system consists of the gastrointestinal tract, sometimes referred to as the ''GI tract,'' which includes the esophagus, stomach, small intestine and large intestine as well as the accessory organs of digestion which include the pancreas, gallbladder, and liver. The digestive system functions to move material through the GI tract via peristalsis, break down that material via digestion, absorb nutrients for use throughout the body, and remove waste from the body via defecation. Physicians who specialize in the medical specialty of gastroenterology are called gastroenterologists or sometimes ''GI doctors''. Some of the most common conditions managed by gastroenterologists include gastroesophageal reflux disease, gastrointestinal bleeding, irritable bowel syndrome, inflammatory bowel disease (IBD ...
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Duodenum
The duodenum is the first section of the small intestine in most vertebrates, including mammals, reptiles, and birds. In mammals, it may be the principal site for iron absorption. The duodenum precedes the jejunum and ileum and is the shortest part of the small intestine. In humans, the duodenum is a hollow jointed tube about long connecting the stomach to the jejunum, the middle part of the small intestine. It begins with the duodenal bulb, and ends at the duodenojejunal flexure marked by the suspensory muscle of duodenum. The duodenum can be divided into four parts: the first (superior), the second (descending), the third (transverse) and the fourth (ascending) parts. Overview The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear, and the terms ''anterior intestine'' or ''proximal intestine'' may be used instead of duodenum. In mammals the d ...
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Foramen Caecum (tongue)
The tongue is a muscular organ in the mouth of a typical tetrapod. It manipulates food for chewing and swallowing as part of the digestive process, and is the primary organ of taste. The tongue's upper surface (dorsum) is covered by taste buds housed in numerous lingual papillae. It is sensitive and kept moist by saliva and is richly supplied with nerves and blood vessels. The tongue also serves as a natural means of cleaning the teeth. A major function of the tongue is to enable speech in humans and vocalization in other animals. The human tongue is divided into two parts, an oral part at the front and a pharyngeal part at the back. The left and right sides are also separated along most of its length by a vertical section of fibrous tissue (the lingual septum) that results in a groove, the median sulcus, on the tongue's surface. There are two groups of glossal muscles. The four intrinsic muscles alter the shape of the tongue and are not attached to bone. The four paired extri ...
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